JPH2

  • Official Full Name

    junctophilin 2
  • Overview

    Junctophilin 2, also known as JPH2, is a protein which in humans is encoded by the JPH2 gene.Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described.
  • Synonyms

    JPH2;junctophilin 2;JP2

Recombinant Proteins

  • Rat
  • Zebrafish
  • Mouse
  • Human
  • Mammalian Cells
  • HEK293
  • E.coli
  • His
  • Avi
  • Fc
  • Flag
  • DDK
  • Myc
  • GST

    Involved Pathway

    JPH2 involved in several pathways and played different roles in them. We selected most pathways JPH2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with JPH2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    JPH2 has several biochemical functions, for example, calcium-release channel activity,phosphatidic acid binding,phosphatidylinositol-3,4,5-trisphosphate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by JPH2 itself. We selected most functions JPH2 had, and list some proteins which have the same functions with JPH2. You can find most of the proteins on our site.

    Function Related Protein
    phosphatidic acid binding MAPKAP1,MARK1,PACSIN2,COMMD1,MICALL1,NRGN,UQCC3,SESTD1,RAPGEF6,PLCD1
    phosphatidylinositol-3-phosphate binding NCF4,VPS36,SNX13,SH3PXD2B,PARD3,PHLDA3,D6WSU116E,LANCL2,WDR45L,WIPI1
    phosphatidylinositol-3,5-bisphosphate binding SH3PXD2B,CLVS2,WIPI2,FAM21C,COMMD1,GBF1,PHLDA3,CLVS1,MAPKAP1,WDR45
    phosphatidylinositol-4-phosphate binding ARFIP1,ARFIP2,PLEKHF1,OSBPL5,FAM21C,SNX3,MBL1,SNX24,RS1,D6WSU116E
    protein binding DDX6,SEPT1,GSDMD,ACTL7A,CDC73,AACS,KIAA1967,FAM49B,NUPL1,KLHL20
    phosphatidylinositol-4,5-bisphosphate binding SNX21,SNX18,D6WSU116E,KCNQ1,FCHO2,RAB35,TULP1,FRMPD4,VIL1,ASAP1
    phosphatidylinositol-3,4,5-trisphosphate binding PIRT,AKT1,FAM21C,ARAP1,ARAP3,OGT,GBF1,PARD3,DAPP1,MAPKAP1
    phosphatidylinositol-5-phosphate binding PHLDA3,RS1,FAM21C,SH3PXD2B,PLEKHF1,WIPI2,D6WSU116E,SNX24,SNX3,LANCL2
    calcium-release channel activity TRPV1,RASA3,RYR3,RYR1,RYR2,JPH3

    Interacting Protein

    JPH2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with JPH2 here. Most of them are supplied by our site. Hope this information will be useful for your research of JPH2.

    TRPC3;Trpc3;HTT;Ywhae

    Resources

    References

    • Weisleder, N; Takeshima, H; et al. Immuno-proteomic approach to excitation-contraction coupling in skeletal and cardiac muscle: Molecular insights revealed by the mitsugurnins. CELL CALCIUM 43:1-8(2008).

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