KCND3

  • Official Full Name

    KCND3 potassium voltage-gated channel, Shal-related subfamily, member 3

  • Background

    Potassium voltage-gated channel subfamily D member 3 also known as Kv4.3 is a protein that in humans is encoded by the KCND3 gene. It contributes to the cardiac transient outward potassium current, the main contributing current to the repolarizing phase 1 of the cardiac action potential.
  • Synonyms

    KCND3; potassium voltage-gated channel, Shal-related subfamily, member 3; potassium voltage-gated channel subfamily D member 3; KSHIVB; Kv4.3; voltage-gated K+ channel; potassium ionic channel Kv4.3; sha1-related potassium channel Kv4.3; voltage-gated potassium channel subunit Kv4.3; KV4.3; KCND3L; KCND3S; MGC142035; MGC142037;
    • Type:
    • Cell & Tissue Lysates
    • Recombinant Proteins
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Chicken
    • Homo sapiens (Human)
    • Human
    • Oryctolagus cuniculus (Rabbit)
    • Rat
    • Rattus norvegicus (Rat)
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli expression system
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • His (Fc)
    • Avi
    • N/A
    Species Cat.# Product name Source (Host) Tag Price
    Human KCND3-5068HCL Recombinant Human KCND3 293 Cell Lysate HEK293 N/A
    Rat KCND3-3176R Recombinant Rat KCND3 Protein Mammalian Cell His
    Rat KCND3-2832R Recombinant Rat KCND3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rat KCND3-2832R-B Recombinant Rat KCND3 Protein Pre-coupled Magnetic Beads HEK293
    Homo sapiens (Human) RFL1467HF Recombinant Full Length Human Potassium Voltage-Gated Channel Subfamily D Member 3(Kcnd3) Protein, His-Tagged E.coli expression system His
    Oryctolagus cuniculus (Rabbit) RFL26481OF Recombinant Full Length Rabbit Potassium Voltage-Gated Channel Subfamily D Member 3(Kcnd3) Protein, His-Tagged E.coli expression system His
    Rattus norvegicus (Rat) RFL3568RF Recombinant Full Length Rat Potassium Voltage-Gated Channel Subfamily D Member 3(Kcnd3) Protein, His-Tagged E.coli expression system His
    Rhesus Macaque KCND3-2350R Recombinant Rhesus monkey KCND3 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque KCND3-2171R Recombinant Rhesus Macaque KCND3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rhesus Macaque KCND3-2171R-B Recombinant Rhesus Macaque KCND3 Protein Pre-coupled Magnetic Beads HEK293
    Zebrafish KCND3-10188Z Recombinant Zebrafish KCND3 Mammalian Cell His
    Chicken KCND3-5899C Recombinant Chicken KCND3 Mammalian Cell His
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • KCND3 Related Articles

    KCND3 involved in several pathways and played different roles in them. We selected most pathways KCND3 participated on our site, such as Neuronal System, Potassium Channels, Voltage gated Potassium channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with KCND3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Neuronal SystemSLC6A11;KCNG4A;KCNV1;KCNK1B;KCNMB2;KCNA10;KCNAB1;CHRNA3;GRIP1
    Potassium ChannelsKCNJ1B;KCNN1B;KCND2;KCNC1;KCNA6;KCNQ2A;KCNJ1A.4;KCNC2;ABCC9
    Voltage gated Potassium channelsKCNG3;KCNC3A;KCNAB1A;KCNH2A;KCNH1;KCNA5;KCNAB2;KCNH6A;KCNAB1

    KCND3 has several biochemical functions, for example, contributes_to A-type (transient outward) potassium channel activity, NOT delayed rectifier potassium channel activity, ion channel binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KCND3 itself. We selected most functions KCND3 had, and list some proteins which have the same functions with KCND3. You can find most of the proteins on our site.

    Function Related Protein
    contributes_to A-type (transient outward) potassium channel activityKCNIP2;KCND3
    NOT delayed rectifier potassium channel activityKCND2;KCND3;KCNA4
    ion channel bindingTCAP;PRKCSH;FAM115A;KCNE2;CAMK2D;SUMO1;USP10;FGF13;KCNAB1
    metal ion bindingTRIM59;CYP1C2;CA14;TAX1BP1;CYP8B2;MBLAC2;TRIM50;ZNFL2A;ATP13A1
    protein bindingSNX17;FCNA;C1QB;HNRPLL;CLUAP1;CD99L2;APOBEC3C;SIGLEC8;MAPKAPK2

    KCND3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCND3 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCND3.

    KCNIP1

    Perrin, MJ; Adler, A; et al. Evaluation of Genes Encoding for the Transient Outward Current (Ito) Identifies the KCND2 Gene as a Cause of J-Wave Syndrome Associated With Sudden Cardiac Death. CIRCULATION-CARDIOVASCULAR GENETICS 7:782-U123(2014).
    Klinck, R; Fourrier, A; et al. RBFOX1 Cooperates with MBNL1 to Control Splicing in Muscle, Including Events Altered in Myotonic Dystrophy Type 1. PLOS ONE 9:-(2014).
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