KCND3

Official Full Name

KCND3 potassium voltage-gated channel, Shal-related subfamily, member 3
Background

Potassium voltage-gated channel subfamily D member 3 also known as Kv4.3 is a protein that in humans is encoded by the KCND3 gene. It contributes to the cardiac transient outward potassium current, the main contributing current to the repolarizing phase 1 of the cardiac action potential.
Synonyms

KCND3; potassium voltage-gated channel, Shal-related subfamily, member 3; potassium voltage-gated channel subfamily D member 3; KSHIVB; Kv4.3; voltage-gated K+ channel; potassium ionic channel Kv4.3; sha1-related potassium channel Kv4.3; voltage-gated potassium channel subunit Kv4.3; KV4.3; KCND3L; KCND3S; MGC142035; MGC142037;

Type:
Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species :
Chicken
Homo sapiens (Human)
Human
Oryctolagus cuniculus (Rabbit)
Rat
Rattus norvegicus (Rat)
Rhesus Macaque
Zebrafish

Source :
E.coli expression system
HEK293
Mammalian Cell

Tag :
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	KCND3-5068HCL	Recombinant Human KCND3 293 Cell Lysate	HEK293	N/A	Inquiry
Rat	KCND3-3176R	Recombinant Rat KCND3 Protein	Mammalian Cell	His	Inquiry
Rat	KCND3-2832R	Recombinant Rat KCND3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	KCND3-2832R-B	Recombinant Rat KCND3 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Homo sapiens (Human)	RFL1467HF	Recombinant Full Length Human Potassium Voltage-Gated Channel Subfamily D Member 3(Kcnd3) Protein, His-Tagged	E.coli expression system	His	Inquiry
Oryctolagus cuniculus (Rabbit)	RFL26481OF	Recombinant Full Length Rabbit Potassium Voltage-Gated Channel Subfamily D Member 3(Kcnd3) Protein, His-Tagged	E.coli expression system	His	Inquiry
Rattus norvegicus (Rat)	RFL3568RF	Recombinant Full Length Rat Potassium Voltage-Gated Channel Subfamily D Member 3(Kcnd3) Protein, His-Tagged	E.coli expression system	His	Inquiry
Rhesus Macaque	KCND3-2350R	Recombinant Rhesus monkey KCND3 Protein, His-tagged	Mammalian Cell	His	Inquiry
Rhesus Macaque	KCND3-2171R	Recombinant Rhesus Macaque KCND3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rhesus Macaque	KCND3-2171R-B	Recombinant Rhesus Macaque KCND3 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Zebrafish	KCND3-10188Z	Recombinant Zebrafish KCND3	Mammalian Cell	His	Inquiry
Chicken	KCND3-5899C	Recombinant Chicken KCND3	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
KCND3 Related Articles

KCND3 involved in several pathways and played different roles in them. We selected most pathways KCND3 participated on our site, such as Neuronal System, Potassium Channels, Voltage gated Potassium channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with KCND3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Neuronal System	SLC6A11;KCNG4A;KCNV1;KCNK1B;KCNMB2;KCNA10;KCNAB1;CHRNA3;GRIP1
Potassium Channels	KCNJ1B;KCNN1B;KCND2;KCNC1;KCNA6;KCNQ2A;KCNJ1A.4;KCNC2;ABCC9
Voltage gated Potassium channels	KCNG3;KCNC3A;KCNAB1A;KCNH2A;KCNH1;KCNA5;KCNAB2;KCNH6A;KCNAB1

KCND3 has several biochemical functions, for example, contributes_to A-type (transient outward) potassium channel activity, NOT delayed rectifier potassium channel activity, ion channel binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KCND3 itself. We selected most functions KCND3 had, and list some proteins which have the same functions with KCND3. You can find most of the proteins on our site.

Function	Related Protein
contributes_to A-type (transient outward) potassium channel activity	KCNIP2;KCND3
NOT delayed rectifier potassium channel activity	KCND2;KCND3;KCNA4
ion channel binding	TCAP;PRKCSH;FAM115A;KCNE2;CAMK2D;SUMO1;USP10;FGF13;KCNAB1
metal ion binding	TRIM59;CYP1C2;CA14;TAX1BP1;CYP8B2;MBLAC2;TRIM50;ZNFL2A;ATP13A1
protein binding	SNX17;FCNA;C1QB;HNRPLL;CLUAP1;CD99L2;APOBEC3C;SIGLEC8;MAPKAPK2

KCND3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCND3 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCND3.

KCNIP1

Perrin, MJ; Adler, A; et al. Evaluation of Genes Encoding for the Transient Outward Current (Ito) Identifies the KCND2 Gene as a Cause of J-Wave Syndrome Associated With Sudden Cardiac Death. CIRCULATION-CARDIOVASCULAR GENETICS 7:782-U123(2014).

Klinck, R; Fourrier, A; et al. RBFOX1 Cooperates with MBNL1 to Control Splicing in Muscle, Including Events Altered in Myotonic Dystrophy Type 1. PLOS ONE 9:-(2014).