KCNQ3

  • Official Full Name

    potassium voltage-gated channel, KQT-like subfamily, member 3
  • Synonyms

    KCNQ3;potassium voltage-gated channel, KQT-like subfamily, member 3;EBN2;potassium voltage-gated channel subfamily KQT member 3;Kv7.3;potassium channel subunit alpha KvLQT3;voltage-gated potassium channel subunit Kv7.3;potassium channel, voltage-ga
Cat.# Product name Source (Host) Species Tag Protein Length Price
KCNQ3-280H Recombinant Human KCNQ3, His-tagged E.coli Human His 379-517aa
KCNQ3-3223R Recombinant Rat KCNQ3 Protein Mammalian Cells Rat His
KCNQ3-5018HCL Recombinant Human KCNQ3 293 Cell Lysate HEK293 Human Non
KCNQ3-2879R Recombinant Rat KCNQ3 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
KCNQ3-2879R-B Recombinant Rat KCNQ3 Protein Pre-coupled Magnetic Beads HEK293 Rat

    Involved Pathway

    KCNQ3 involved in several pathways and played different roles in them. We selected most pathways KCNQ3 participated on our site, such as Axon guidance,Cholinergic synapse,Developmental Biology, which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNQ3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Developmental Biology FGF8B,AP2S1,SPTB,FGF20A,MED18,MED10,TDGF1,MYL12A,TCF3A,CDON
    Cholinergic synapse ITPR1,KCNJ4,CAMK4,CAMK2G,KCNQ1,AKT2,KCNQ5,PIK3R2,MAPK1,CREB3L2
    Voltage gated Potassium channels KCNAB3,KCNA4,KCNC4,KCNA2B,KCNG4A,KCNQ2A,KCNC1B,KCNH2,KCNB2,KCNV1
    L1CAM interactions KCNQ2,DLG3,NRP2,CNTN6,NADL1.1,CNTN1,CD24,ANK2B,SCN9A,SDCBP
    Potassium Channels KCNJ1B,KCNH5,KCNH6A,KCNK13B,KCNC1,KCNA6A,KCNA6,KCNN1,KCNAB1,HCN4
    Axon guidance EFNA2,EPHA1,MYL9,NRG4,GNAI3,EFNB3,TRIO,EPHB4A,MET,NTN4
    Neuronal System KCNJ1A.2,KCNC1A,CHRNA4,KCNH1,KCNJ1A.3,KCNG3,KCNK2B,KCNC1,KCNAB1,KCNQ1
    Interaction between L1 and Ankyrins SCN8A,KCNQ2,SCN2B,SCN4A,SCN9A,ANK2B,SCN3B,NADL1.1,SCN3A,SCN2A

    Protein Function

    KCNQ3 has several biochemical functions, for example, calmodulin binding,delayed rectifier potassium channel activity,ion channel binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNQ3 itself. We selected most functions KCNQ3 had, and list some proteins which have the same functions with KCNQ3. You can find most of the proteins on our site.

    Function Related Protein
    protein kinase binding HIF1A,STX1B,SPAG16,LATS1,SMAD3,TENC1,SPRY2,PIH1D1,ILK,USP37
    ubiquitin protein ligase binding FAF1,TRIB3,GPR37,ATP6V0C,TRP53,FANCL,TRAF3,UBE2N,TRIM28,PRKAR1A
    ion channel binding PDE4D,ID2,DIAP1,PKD2,FGF13,PKP2,KCNIP2,KCNH5,FHL1,AP2M1
    calmodulin binding AEBP1,TRPC2,MKNK2A,CALD1B,PHKA1,PPP3CC,PNCK,SNTB1,PATE4,MAP2
    potassium channel activity KCNK1A,KCNQ2,KCNC3B,KCNA2,KCNQ2A,KCNA6A,KCNIP1,KCNK5A,KCNK15,KCNK2B
    voltage-gated potassium channel activity CNGA2,HCN4,KCNH1A,KCNAB1,CNGA1,KCNJ11,KCNV2B,KCNC1,KCNAB2,KCNH2
    delayed rectifier potassium channel activity KCNQ2,KCND1,KCNB1,KCNV2B,KCNG3,KCNQ1,KCNA5,KCNV2,KCNC3A,KCNA2

    Interacting Protein

    KCNQ3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNQ3 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNQ3.

    Resources

    References

    • Bocksteins, E; Van de Vijver, G; et al. K(v)3 channels contribute to the delayed rectifier current in small cultured mouse dorsal root ganglion neurons. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 303:C406-C415(2012).
    • Stewart, AP; Gomez-Posada, JC; et al. The Kv7.2/Kv7.3 Heterotetramer Assembles with a Random Subunit Arrangement. JOURNAL OF BIOLOGICAL CHEMISTRY 287:11870-11877(2012).

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