KCNQ3

  • Official Full Name

    potassium voltage-gated channel, KQT-like subfamily, member 3
  • Synonyms

    KCNQ3;potassium voltage-gated channel, KQT-like subfamily, member 3;EBN2;potassium voltage-gated channel subfamily KQT member 3;Kv7.3;potassium channel subunit alpha KvLQT3;voltage-gated potassium channel subunit Kv7.3;potassium channel, voltage-ga
Cat.# Product name Source (Host) Species Tag Protein Length Price
KCNQ3-280H Recombinant Human KCNQ3 protein, His-tagged E.coli Human His
KCNQ3-3223R Recombinant Rat KCNQ3 Protein Mammalian Cells Rat His
KCNQ3-5018HCL Recombinant Human KCNQ3 293 Cell Lysate HEK293 Human Non
KCNQ3-2879R Recombinant Rat KCNQ3 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
KCNQ3-2879R-B Recombinant Rat KCNQ3 Protein Pre-coupled Magnetic Beads HEK293 Rat
KCNQ3-5733H Recombinant Human KCNQ3 protein, GST-tagged E.coli Human GST

    Involved Pathway

    KCNQ3 involved in several pathways and played different roles in them. We selected most pathways KCNQ3 participated on our site, such as Axon guidance,Cholinergic synapse,Developmental Biology, which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNQ3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Voltage gated Potassium channels KCNV2,KCNH8,KCNAB2,KCNAB3,KCNF1,KCND3,KCNH1,KCNH5,KCNC2,KCNC1A
    Potassium Channels KCNC2,KCNK2B,KCNN3,KCNN1B,KCNK4,KCNK13B,KCNN1A,KCNG4A,KCNJ1A.5,KCNA10
    Developmental Biology NR6A1,NRG2A,COL6A1,CNKSR1,NR5A1,CACNG8A,KDR,BOC,SHB,SCN4A
    Neuronal System GJC1,LIN7A,HCN4,UNC13B,SLC1A2A,KCNH6,KCND1,KCND2,KCNMA1,ABCC9
    Interaction between L1 and Ankyrins NADL1.1,KCNQ2,SCN2B,SCN3B,SCN3A,SCN2A,ANK2B,SCN4A,SCN8A,SCN9A
    Cholinergic synapse KCNJ14,CREB5,CAMK2G,PRKCB,PRKCA,GNB1,GNG8,PIK3CA,AKR1C1,ITPR3
    Axon guidance EFNB2A,GPC1B,DPYSL3,CSF2RA,SHB,MARK3,TRPC7,AGRN,EFNA3B,FGF8B
    L1CAM interactions EZRA,ANK2B,SCN3B,SCN4A,CNTN1,SCN2A,RANBP9,DPYSL2B,SCN3A,KIF4

    Protein Function

    KCNQ3 has several biochemical functions, for example, calmodulin binding,delayed rectifier potassium channel activity,ion channel binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNQ3 itself. We selected most functions KCNQ3 had, and list some proteins which have the same functions with KCNQ3. You can find most of the proteins on our site.

    Function Related Protein
    ubiquitin protein ligase binding PIAS4,SPOP,BECN1,UBE2G1A,SMAD2,ACTG1,HSPA8,CUL3,XRCC5,H2-AB1
    calmodulin binding SLC8A2,ATPIF1,TRPV5,MYO9B,SPTBN1,CNN2,ATP2B1,CAMSAP1L1,RIT1,CNN1
    potassium channel activity KCNK5,TMEM38B,KCNK7,KCNC3B,KCNQ2A,KCNK1A,ABCC9,KCNG1,KCNK10,KCNV2B
    protein kinase binding IL12RB2,GHR,GRB2,HCLS1,GSK3B,GYS1,RELA,PPP1R12B,ADRA2A,NCS1
    delayed rectifier potassium channel activity KCNC2,KCND1,KCNQ5,KCNC3A,KCNG1,KCNB2,KCNE1,KCNQ2,KCNA1,KCNS3
    voltage-gated potassium channel activity KCNA6A,KCNMA1A,CNGA5,KCNC1,KCNB2,KCNE3,KCND2,KCNQ5,KCNH6A,HCN4
    ion channel binding KCNE4,KCNE2,CAV1,SRI,FGF12,SCN5A,S100A10,ACTN3,GPD1L,FHL1

    Interacting Protein

    KCNQ3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNQ3 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNQ3.

    Resources

    References

    • Bocksteins, E; Van de Vijver, G; et al. K(v)3 channels contribute to the delayed rectifier current in small cultured mouse dorsal root ganglion neurons. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 303:C406-C415(2012).
    • Stewart, AP; Gomez-Posada, JC; et al. The Kv7.2/Kv7.3 Heterotetramer Assembles with a Random Subunit Arrangement. JOURNAL OF BIOLOGICAL CHEMISTRY 287:11870-11877(2012).

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