KCNQ3

  • Official Full Name

    potassium voltage-gated channel, KQT-like subfamily, member 3
  • Synonyms

    KCNQ3;potassium voltage-gated channel, KQT-like subfamily, member 3;EBN2;potassium voltage-gated channel subfamily KQT member 3;Kv7.3;potassium channel subunit alpha KvLQT3;voltage-gated potassium channel subunit Kv7.3;potassium channel, voltage-ga
Cat.# Product name Source (Host) Species Tag Protein Length Price
KCNQ3-280H Recombinant Human KCNQ3, His-tagged E.coli Human His 379-517aa
KCNQ3-3223R Recombinant Rat KCNQ3 Protein Mammalian Cells Rat His
KCNQ3-5018HCL Recombinant Human KCNQ3 293 Cell Lysate HEK293 Human Non
KCNQ3-2879R Recombinant Rat KCNQ3 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
KCNQ3-2879R-B Recombinant Rat KCNQ3 Protein Pre-coupled Magnetic Beads HEK293 Rat

    Involved Pathway

    KCNQ3 involved in several pathways and played different roles in them. We selected most pathways KCNQ3 participated on our site, such as Axon guidance,Cholinergic synapse,Developmental Biology, which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNQ3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Neuronal System ARL6IP5B,KCNQ1,KCNF1,KCNC2,KCNA6,DDX1,CACFD1,KCNQ2A,SLC6A11,GNGT2B
    Axon guidance GSK3B,EFNA3B,JAK3,AP2A2,EPHA2,PPP3CA,NTN1,SPNA1,MARK3,PLXNA3
    Developmental Biology DPYSL5A,AP2B1,LGI4,KALRN,ADAM22,SREBF2,ARPC5,CARM1,SHB,COL9A1A
    Voltage gated Potassium channels KCNA2,KCNF1A,KCNB2,KCNA5,KCNA2B,KCNAB2,KCND2,KCND1,KCNC2,KCNH2
    Interaction between L1 and Ankyrins SCN8A,SCN2A,KCNQ2,SCN9A,NADL1.1,SCN3A,SCN2B,ANK2B,SCN3B,SCN4A
    Potassium Channels KCNAB3,KCNC1A,KCNQ1,KCNC3A,KCNF1,KCNH2A,KCNA5,KCNF1A,KCNH6,KCND1
    Cholinergic synapse PRKACG,GNG11,NRAS,KCNQ2,CHAT,ITPR3,PIK3R2,GNG10,KCNQ1,KCNJ12
    L1CAM interactions CD24,SCN4A,DLG3,NRP1A,SCN3A,CHL1,SCN2A,DCX,DPYSL2B,NADL1.1

    Protein Function

    KCNQ3 has several biochemical functions, for example, calmodulin binding,delayed rectifier potassium channel activity,ion channel binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNQ3 itself. We selected most functions KCNQ3 had, and list some proteins which have the same functions with KCNQ3. You can find most of the proteins on our site.

    Function Related Protein
    ubiquitin protein ligase binding CASP8,TRIOBP,TUBA1B,BECN1,SCAMP3,PINK1,CBS,UBE2B,VCP,CUL4A
    potassium channel activity KCNA6A,AQP1,KCNF1,KCNF1A,TMEM38B,FXYD4,KCNK3A,PKD2,KCNV2B,KCNA2B
    ion channel binding KCNJ11,PDE4D,SRI,HTT,KCNE2,SLC14A2,PANX1,KCNC1,KCND3,YWHAH
    protein kinase binding CAMK2N1A,LLGL1,PLK1,TUBB3,PAX6,ILK,CD226,NME2,TTN,CACNB3
    voltage-gated potassium channel activity KCNQ1,KCNAB2B,KCNF1A,KCNC1A,KCNB2,KCNK9,CNGA2,KCNAB1A,CNGA1,KCNK5
    delayed rectifier potassium channel activity KCNQ5,KCNQ1,KCNB2,KCNA6,KCNA10,KCNF1,KCNH2,KCNG3,KCNQ2A,KCNG4A
    calmodulin binding TRPV1,ASPM,CNN1A,CAMK1GB,PPP3CA,MYH11,SRY,IQCB1,MAP6,PLCB1

    Interacting Protein

    KCNQ3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNQ3 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNQ3.

    Resources

    References

    • Bocksteins, E; Van de Vijver, G; et al. K(v)3 channels contribute to the delayed rectifier current in small cultured mouse dorsal root ganglion neurons. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 303:C406-C415(2012).
    • Stewart, AP; Gomez-Posada, JC; et al. The Kv7.2/Kv7.3 Heterotetramer Assembles with a Random Subunit Arrangement. JOURNAL OF BIOLOGICAL CHEMISTRY 287:11870-11877(2012).

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