KCNQ3
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Official Full Name
potassium voltage-gated channel, KQT-like subfamily, member 3 -
Synonyms
KCNQ3;potassium voltage-gated channel, KQT-like subfamily, member 3;EBN2;potassium voltage-gated channel subfamily KQT member 3;Kv7.3;potassium channel subunit alpha KvLQT3;voltage-gated potassium channel subunit Kv7.3;potassium channel, voltage-ga
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KCNQ3-280H | Recombinant Human KCNQ3 protein, His-tagged | E.coli | Human | His | ||
| KCNQ3-3223R | Recombinant Rat KCNQ3 Protein | Mammalian Cells | Rat | His |
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| KCNQ3-5018HCL | Recombinant Human KCNQ3 293 Cell Lysate | HEK293 | Human | Non |
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| KCNQ3-2879R | Recombinant Rat KCNQ3 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&Fc&His |
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| KCNQ3-2879R-B | Recombinant Rat KCNQ3 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| KCNQ3-5733H | Recombinant Human KCNQ3 protein, GST-tagged | E.coli | Human | GST |
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Involved Pathway
KCNQ3 involved in several pathways and played different roles in them. We selected most pathways KCNQ3 participated on our site, such as Axon guidance,Cholinergic synapse,Developmental Biology, which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNQ3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Axon guidance | AP2M1,NRP2,PPP3R2,NCK2,SEMA3G,EPHA8,KIF4A,NTNG1,EPHB6,SEMA3E |
| Developmental Biology | CAP1,TRPC5,LGI2B,TDGF1,CSNK2B,MED26,SPRED2,RASGEF1A,PHB,MEF2B |
| Interaction between L1 and Ankyrins | SCN2A,SCN3A,SCN9A,SCN4A,SCN2B,NADL1.1,KCNQ2,SCN8A,SCN3B,ANK2B |
| L1CAM interactions | DCX,KCNQ2,CD24,SCN2A,DPYSL2,SCN3B,SDCBP,ANK2B,KIF4A,SCN8A |
| Neuronal System | SLC6A1A,Apba1,NSFA,KCND3,KCNA2B,MYO6,PANX2,CHRNB4,KCNJ1A.4,CHRNA1 |
| Voltage gated Potassium channels | KCND1,KCNA10,KCNS2,KCNC3A,KCNH8,KCNH1A,KCNA5,KCNA2B,KCNA6A,KCNB2 |
| Cholinergic synapse | PIK3R2,GNB3,CHRM3,GNAQ,CHRM1,GNB1,KCNJ3,KCNQ1,GNB4,CREB3L1 |
| Potassium Channels | KCNA5,KCNK1,KCNC4,KCNK3A,KCNH6A,DDX1,KCNJ1A.6,KCNC3A,KCNH8,KCNA1 |
Protein Function
KCNQ3 has several biochemical functions, for example, calmodulin binding,delayed rectifier potassium channel activity,ion channel binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNQ3 itself. We selected most functions KCNQ3 had, and list some proteins which have the same functions with KCNQ3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ion channel binding | SCN3B,FKBP1B,RANGRF,KCNIP1,PACS1A,VDAC1,KCNQ1,PDE4D,DLG1,S100A10 |
| potassium channel activity | KCNC1B,KCNA2,DDX1,KCNC2,KCNH5,KCNC3A,KCNK1,KCNQ2,KCNG4A,KCNQ4 |
| delayed rectifier potassium channel activity | KCNS3A,KCNA2,KCNQ1,KCNC3B,KCNA5,KCND1,KCNC1A,KCNQ4,KCNS2,KCNQ5 |
| voltage-gated potassium channel activity | KCNC1B,KCNH5A,KCNAB3,KCNH6,KCNAB2,KCNA6A,KCNH1A,KCNG4A,CNGA2,KCNH8 |
| ubiquitin protein ligase binding | HDAC6,TRAF4,RELA,PRKACA,CUL3B,LC3,EGFR,EIF4E2,USP13,UBE2S |
| protein kinase binding | ZFP36,GYS1,CCNY,LLGL1,AKAP1,EPHA1,RAB8A,AP1B1,CRY1,DPYSL2 |
| calmodulin binding | CNN2,MYO1A,RYR1,SMTNL1,SPA17,MTAP6,PCDP1,CAMK1,ASPM,EPB41 |
Interacting Protein
KCNQ3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNQ3 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNQ3.
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References
- Bocksteins, E; Van de Vijver, G; et al. K(v)3 channels contribute to the delayed rectifier current in small cultured mouse dorsal root ganglion neurons. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 303:C406-C415(2012).
- Stewart, AP; Gomez-Posada, JC; et al. The Kv7.2/Kv7.3 Heterotetramer Assembles with a Random Subunit Arrangement. JOURNAL OF BIOLOGICAL CHEMISTRY 287:11870-11877(2012).
