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KIF14

  • Official Full Name

    kinesin family member 14

  • Overview

    KIF14 is a member of the kinesin superfamily of microtubule-associated motors (see MIM 148760) that play important;roles in intracellular transport and cell division (Nakagawa et al., 1997 (PubMed 9275178)).
  • Synonyms

    KIF14; kinesin family member 14; kinesin-like protein KIF14; KIAA0042; KIF 14; Kinesin like protein KIF14; MGC142302;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KIF14-1051H Recombinant Human KIF14 Mammalian Cell His
Human KIF14-925HCL Recombinant Human KIF14 cell lysate N/A
Human KIF14-2360H Recombinant Human KIF14 Protein, His-tagged E.coli N-His Ala1520-Val1648
Human KIF14-3212H Recombinant Human KIF14 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human KIF14-3212H-B Recombinant Human KIF14 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish KIF14-4064Z Recombinant Zebrafish KIF14 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KIF14 Related Articles
  • KIF14 Related Gene Family

KIF14 involved in several pathways and played different roles in them. We selected most pathways KIF14 participated on our site, such as RHO GTPase Effectors, RHO GTPases activate CIT, Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RHO GTPase EffectorsRTKN;RCC2;FMNL1;NUF2;RHPN1;ZWINT;RHOAE;NOXO1A;KDM4C
RHO GTPases activate CITCIT;KIF14;PRC1;PRC1B;RHOAE
Signal TransductionARHGAP17B;NOXO1A;SOX32;NOXO1;SPOP;FGFBP3;RHOU;OR2AP1;CRABP2B
Signaling by Rho GTPasesARHGAP17;ARHGEF18A;ARHGAP12B;TAX1BP3;ARHGAP29;PLEKHG2;RHOUA;ARAP2;KTN1

KIF14 has several biochemical functions, for example, ATP binding, ATP-dependent microtubule motor activity, plus-end-directed, ATPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF14 itself. We selected most functions KIF14 had, and list some proteins which have the same functions with KIF14. You can find most of the proteins on our site.

Function Related Protein
ATP bindingPDK2;HSP104;ZRANB3;DNAH11;BRAF;LACE1;MAPK1;CMPK1;HNRNPU
ATP-dependent microtubule motor activity, plus-end-directedKIF5B;KIF20B;KIF3B;KIF1C;KIF16B;KIF5AA;KIF3A;KIF17;KIF11
ATPase activityABCC12;ABCF1;VPS4B;ABCB1A;ABCA1B;KIF25;PSMC3;ATAD1A;RHOBTB3
PDZ domain bindingARHGAP29;SLC22A12;CXADR;SLC22A5;ACCN3;PTEN;FZD1;PTENA;KIF14
microtubule bindingARL3;MTAP1A;DPYSL5A;CETN1;RACGAP1;LRPPRC;MAPRE3B;TRAF3IP1;HAUS8
microtubule motor activityAPPBP2;DNAI2;DYNC1H1;DNAHC8;KIFC1;KIF3CB;KIF20A;KLC4;KIF12
protein bindingDUSP2;BLOC1S1;FATE1;BBS5;TMEM139;CD36;TATDN1;PDIK1L;SLC30A1
protein kinase bindingPIH1D1;SNAP91;DNAJA3;MAP3K5;TRAF2;MAP2K7;DNAJC3;PAX6;CCNY
tubulin bindingPRNP;STMN4L;KIF14;STMN1B;CLIP1;ALDOA;TTLL6;STMN3;PARK2

KIF14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF14 here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF14.

SVIL; RIPK2; PSTPIP1; Gorasp1; Cit; URB1; ATP5I; HNRNPA1L2; CCDC14; Kif1bp; Trim32; KIF1BP; TSNAX; TUBA1C; KLC4; Naa10; TJP2; TMCO1

Theriault, BL; Cybulska, P; et al. The role of KIF14 in patient-derived primary cultures of high-grade serous ovarian cancer cells. JOURNAL OF OVARIAN RESEARCH 7:-(2014).
Yang, T; Li, XN; et al. Sox17 inhibits hepatocellular carcinoma progression by downregulation of KIF14 expression. TUMOR BIOLOGY 35:11199-11207(2014).
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