KIF2A

  • Official Full Name

    kinesin heavy chain member 2A

  • Overview

    The protein encoded by this gene is a plus end-directed motor required for normal mitotic progression. The encoded protein is required for normal spindle activity during mitosis and is necessary for normal brain development. Several transcript variants encoding different isoforms have been found for this gene.

  • Synonyms

    KIF2A;kinesin heavy chain member 2A;KIF2, kinesin heavy chain member 2;kinesin-like protein KIF2A;HK2;kinesin-2;Kinesin, heavy chain, 2;KIF2

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Chicken
  • Mouse
  • E.coli
  • Mammalian Cells
  • HEK293
  • E. coli
  • GST
  • His
  • Non
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
KIF2A-370H Recombinant Human KIF2A, GST-tagged E.coli Human GST C-term-352aa
KIF2A-2405R Recombinant Rhesus monkey KIF2A Protein, His-tagged Mammalian Cells Rhesus macaque His
KIF2A-3371C Recombinant Chicken KIF2A Mammalian Cells Chicken His
KIF2A-8640M Recombinant Mouse KIF2A Protein Mammalian Cells Mouse His
KIF2A-4947HCL Recombinant Human KIF2A 293 Cell Lysate HEK293 Human Non
KIF2A-2226R Recombinant Rhesus Macaque KIF2A Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
KIF2A-2226R-B Recombinant Rhesus Macaque KIF2A Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
KIF2A-4815M Recombinant Mouse KIF2A Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
KIF2A-4815M-B Recombinant Mouse KIF2A Protein Pre-coupled Magnetic Beads HEK293 Mouse
KIF2A-6743H Recombinant Human KIF2A protein, GST-tagged E. coli Human GST
KIF2A-6744H Recombinant Human KIF2A protein, GST-tagged E. coli Human GST

    Involved Pathway

    KIF2A involved in several pathways and played different roles in them. We selected most pathways KIF2A participated on our site, such as Adaptive Immune System,Cell Cycle,Cell Cycle, Mitotic, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell Cycle, Mitotic WAPAL,CENPK,GINS4,SSNA1,VRK1,ODF2,VRK2,ACTR1A,DULLARD,CDKN2A
    Hemostasis DGKG,HBD,PHF21A,D-AKAP2,STXBP3,VPS45,F3B,KIF5B,KIFC1,CXADR
    Factors involved in megakaryocyte development and platelet production AKAP10,KIF2B,KIF15,H3F3B.1,DOCK6,KDM1A,LRRC16A,NFE2,KIF9,DOCK1
    Adaptive Immune System CLTC,SPSB4,KIF3A,FGFR1B,UBE2V2,Siglece,TRIM69,TREML2,SEC24A,IGKV1-5
    M Phase PMF1,ENSAB,TMPO,KIF18A,GORASP2,MAU2,NCAPH2,NDEL1A,SPC24,SPC25
    Cell cycle KAT5,GOLGA2,DIDO1,GADD45AA,TUBGCP5,SGOL1,SYCE1,CDC6,MIS18A,MYC
    Kinesins KIF3B,KIF9,KIF18A,KIF5A,KIF26A,CENPE,KIF15,KIF11,KIF22,KIF20A
    Immune System RNF220,ATG7,PCBP2,FBXO27,IgG3,KLHL21,IFIT8,MGC174155,ABI1B,CTSE

    Protein Function

    KIF2A has several biochemical functions, for example, ATP binding,ATPase activity,microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF2A itself. We selected most functions KIF2A had, and list some proteins which have the same functions with KIF2A. You can find most of the proteins on our site.

    Function Related Protein
    microtubule binding ARHGEF2,CEP57L1,POLB,MTAP1B,SKA2,KIF25,KCNH2A,JAKMIP1,KATNAL1,DPYSL2B
    protein binding VIM,FBF1,GIP,RAB18,RIPK1L,ACCS,RPP30,ELK3,XIRP2,AKR7A3
    ATPase activity KIF15,PSMD6,KIF12,NSFA,HLTF,PSMC4,EIF4A2,ATAD2B,PMS1,ABCD3A
    motor activity KIF5A,MYH11,MYHZ1.1,DYNLL1,MYH1B,DYNLT1,VMHC,MYO1G,MYH4,CGNL1
    ATP binding MKNK2B,RHOBTB3,PTK2AA,ABCG3,TIMM44,LATS2,PRKX,DDX39B,LIMK2,MYLK3
    microtubule motor activity APPBP2,KLC1B,DNHD1,DYNC1H1,DYNC1I1,KIF7,DNAHC8,KIF25,DYNC1LI2,DNAH14

    Interacting Protein

    KIF2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF2A here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF2A.

    LARP1B;FAM13C;MRPL53;MYB;pi3p;ssrna_ug;EIF3F;KIAA0556;EXOC3;LTN1;UBR5;UBL4A

    Resources

    Gene Families

    References

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