kif2a
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  • Official Full Name
  • kinesin heavy chain member 2A
  • Background
  • The protein encoded by this gene is a plus end-directed motor required for normal mitotic progression. The encoded protein is required for normal spindle activity during mitosis and is necessary for normal brain development. Several transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • KIF2A; kinesin heavy chain member 2A; KIF2, kinesin heavy chain member 2; kinesin-like protein KIF2A; HK2; kinesin-2; Kinesin, heavy chain, 2; KIF2
Cat.#:KIF2A-370HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human KIF2A, GST-tagged
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Cat.#:KIF2A-8640MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse KIF2A Protein
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Cat.#:KIF2A-2405RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey KIF2A Protein, His-tagged
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Cat.#:KIF2A-3371CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken KIF2A
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Cat.#:KIF2A-4947HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human KIF2A 293 Cell Lysate
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Involved Pathway

KIF2A involved in several pathways and played different roles in them. We selected most pathways KIF2A participated on our site, such as Adaptive Immune System, Cell Cycle, Cell Cycle, Mitotic, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adaptive Immune System
SPTBN2; FRS2A; LILRB4; FCGR1B; CD300E; PJA2; RNF138; MALT1; DCTN2; CLEC2H
Cell Cycle
MCM6; CUL1; VRK1; NCAPG2; H3F3B.1; MAU2; MCM9; ORC3L; CDK4; HDAC5
Cell Cycle, Mitotic
CDK11B; NCAPH2; NIPBLA; RBBP4; DCTN1; ESCO1; MCM8; SPDL1; PHF8; PDS5A
Factors involved in megakaryocyte development and platelet production
HBD; MFN1; KDM1A; IRF2A; CABLES1; MAFGB; RACGAP1; HBE1; KIF11; DOCK11
Hemostasis
AKAP1B; BA2; AKAP10; STXBP3A; HBE1; FN1B; ANXA2; S100A10A; APOA1B; HRG
Immune System
HBL3; AP1S3A; ASB7; POLR3H; USP18; BST2; CXADR; DUSP3B; CASP4; CD300LG
Kinesins
KIFC1; KIF15; CENPE; KIF5A; KIF26A; KIF2C; KIF4; KIF3B; KIF20A; KIF2A
M Phase
SET; SPC25; PHF8; VRK1; CENPE; ZWILCH; ARPP19A; WAPAL; SKA1; AHCTF1

Protein Function

KIF2A has several biochemical functions, for example, ATP binding, ATPase activity, microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF2A itself. We selected most functions KIF2A had, and list some proteins which have the same functions with KIF2A. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein ALDH18A1; MAP2K3; NAV3; YSK4; MCM2; SUCLG2; MAPK1; MSH4; CDK11B; DNAH14
Function ATPase activity
Related Protein ATAD2B; KIF6; ERCC3; ATAD1B; ABCG2B; ATAD1A; ABCB3L1; CHD1L; DYNC1H1; SWSAP1
Function microtubule binding
Related Protein FGF13; MAPT; KIF26A; NUSAP1; CEP57L1; WDR81; S100A8; EML1; RPS3; KIF15
Function microtubule motor activity
Related Protein KIF2C; KIFC2; KIF22; KIF25; KLC4; DNAI2; DYNC1H1; DNAH5; DYNC1I2; KIF2A
Function motor activity
Related Protein MYO5A; KIF18B; VMHCL; MYH1; CGNB; MYO1C; DYNC2H1; MYO6A; MYHZ1.1; MYH7B
Function protein binding
Related Protein C14orf118; SUPT4H1; ACY1; ALG13; NETO2; CCDC141; ARHGEF40; SPN; pab1; PEX10

Interacting Protein

KIF2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF2A here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF2A.
LARP1B; FAM13C; MRPL53; MYB; pi3p; ssrna_ug; EIF3F; KIAA0556; EXOC3; LTN1; UBR5; UBL4A

KIF2A Related Gene Family

Kinesins (KIF)