KRT75

Official Full Name

keratin 75
Overview

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. This gene is expressed in the companion layer, upper germinative matrix region of the hair follicle, and medulla of the hair shaft. The encoded protein plays an essential role in hair and nail formation. Variations in this gene have been associated with the hair disorders pseudofolliculitis barbae (PFB) and loose anagen hair syndrome (LAHS).
Synonyms

KRT75; keratin 75; K6hf; Keratin K75; PFB; K6HF; KB18; keratin, type II cytoskeletal 75; K75; CK-75; hK6hf; keratin-75; cytokeratin-75; type II keratin-18; cytokeratin type II; type II keratin-K6hf; type-II keratin Kb18; keratin-6 hair follicle;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rat

Source

HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	KRT75-4839H	Recombinant Human KRT75 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	KRT75-6088HF	Recombinant Full Length Human KRT75 Protein, GST-tagged	In Vitro Cell Free System	GST	551 amino acids	Inquiry
Mouse	KRT75-8850M	Recombinant Mouse KRT75 Protein	Mammalian Cell	His		Inquiry
Mouse	KRT75-4938M-B	Recombinant Mouse KRT75 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	KRT75-4938M	Recombinant Mouse KRT75 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Rat	KRT75-3330R	Recombinant Rat KRT75 Protein	Mammalian Cell	His		Inquiry
Rat	KRT75-2986R	Recombinant Rat KRT75 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Rat	KRT75-2986R-B	Recombinant Rat KRT75 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Chicken	KRT75-1094C	Recombinant Chicken KRT75	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

KRT75 involved in several pathways and played different roles in them. We selected most pathways KRT75 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KRT75 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

KRT75 has several biochemical functions, for example, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KRT75 itself. We selected most functions KRT75 had, and list some proteins which have the same functions with KRT75. You can find most of the proteins on our site.

Function	Related Protein
structural molecule activity	SPRR1B;KRT19;CLDN3;INAA;KRT93;COL15A1B;KRT28;EPB41L3B;KRT4

KRT75 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KRT75 here. Most of them are supplied by our site. Hope this information will be useful for your research of KRT75.

Hmga2

Research Area

Stockman, DL; Hornick, JL; et al. ERG and FLI1 protein expression in epithelioid sarcoma. MODERN PATHOLOGY 27:496-501(2014).

Li, QX; Cui, WL; et al. Application of Immunohistochemistry in the Diagnosis of Small Round Blue-Cell Tumors of Soft Tissue. CLINICAL LABORATORY 60:1383-1392(2014).