|Official Full Name||keratin 75|
|Background||This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. This gene is expressed in the companion layer, upper germinative matrix region of the hair follicle, and medulla of the hair shaft. The encoded protein plays an essential role in hair and nail formation. Variations in this gene have been associated with the hair disorders pseudofolliculitis barbae (PFB) and loose anagen hair syndrome (LAHS).|
|Synonyms||KRT75; keratin 75; K6hf; Keratin K75; PFB; K6HF; KB18; keratin, type II cytoskeletal 75; K75; CK-75; hK6hf; keratin-75; cytokeratin-75; type II keratin-18; cytokeratin type II; type II keratin-K6hf; type-II keratin Kb18; keratin-6 hair follicle|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
KRT75 involved in several pathways and played different roles in them. We selected most pathways KRT75 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KRT75 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
KRT75 has several biochemical functions, for example, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KRT75 itself. We selected most functions KRT75 had, and list some proteins which have the same functions with KRT75. You can find most of the proteins on our site.
|structural molecule activity||CLDN12; IFLTD1; MAP7D2A; SYNC; TUBB5; SPRR1B; KLHL3; LOR; TUBGCP3; LAMA2|
KRT75 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KRT75 here. Most of them are supplied by our site. Hope this information will be useful for your research of KRT75.