Recombinant Human KRT75 Protein, GST-tagged

• Cat.No.: KRT75-4839H
• Product Overview: Human KRT75 full-length ORF (AAI60175.1, 1 a.a. - 551 a.a.) recombinant protein with GST tag at N-terminal.

Specification

• Description: This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. This gene is expressed in the companion layer, upper germinative matrix region of the hair follicle, and medulla of the hair shaft. The encoded protein plays an essential role in hair and nail formation. Variations in this gene have been associated with the hair disorders pseudofolliculitis barbae (PFB) and loose anagen hair syndrome (LAHS). [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 87.1 kDa
• AA Sequence: MSRQSSITFQSGSRRGFSTTSAITP AAGRSRFSSVSVARSAAGSGGLGRI SSAGASFGSRSLYNLGGAKRVSING CGSSCRSGFGGRASNRFGVNSGFGY GGGVGGGFSGPSFPVCPPGGIQEVT VNQSLLTPLHLQIDPTIQRVRAEER EQIKTLNNKFASFIDKVRFLEQQNK VLETKWALLQEQGSRTVRQNLEPLF DSYTSELRRQLESITTERGRLEAEL RNMQDVVEDFKVRYEDEINKRTAAE NEFVALKKDVDAAYMNKVELEAKVK SLPEEINFIHSVFDAELSQLQTQVG DTSVVLSMDNNRNLDLDSIIAEVKA QYEDIANRSRAEAESWYQTKYEELQ VTAGRHGDDLRNTKQEISEMNRMIQ RLRAEIDSVKKQCSSLQTAIADAEQ RGELALKDARAKLVDLEEALQKAKQ DMARLLREYQELMNIKLALDVEIAT YRKLLEGEECRLSGEGVSPVNISVV TSTLSSGYGSGSSIGGGNLGLGGGS GYSFTTSGGHSLGAGLGGSGFSATS NRGLGGSGSSVKFVSTTSSSQKSYT H
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: KRT75 keratin 75 [ Homo sapiens ]
• Official Symbol: KRT75
• Synonyms: KRT75; keratin 75; keratin, type II cytoskeletal 75; K6HF; K75; CK-75; hK6hf; keratin-75; cytokeratin-75; type II keratin-18; cytokeratin type II; type II keratin-K6hf; type-II keratin Kb18; keratin-6 hair follicle; PFB; KB18
• Gene ID: 9119
• mRNA Refseq: NM_004693
• Protein Refseq: NP_004684
• MIM: 609025
• UniProt ID: O95678