Recombinant Human KRT75 Protein, GST-tagged KRT75-4839H

Recombinant Human KRT75 Protein, GST-tagged

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Recombinant Human KRT75 Protein, GST-tagged

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Cat.No. : KRT75-4839H
Product Overview : Human KRT75 full-length ORF (AAI60175.1, 1 a.a. - 551 a.a.) recombinant protein with GST tag at N-terminal.
Description : This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. This gene is expressed in the companion layer, upper germinative matrix region of the hair follicle, and medulla of the hair shaft. The encoded protein plays an essential role in hair and nail formation. Variations in this gene have been associated with the hair disorders pseudofolliculitis barbae (PFB) and loose anagen hair syndrome (LAHS). [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 87.1 kDa
AA Sequence : MSRQSSITFQSGSRR GFSTTSAITPAAGRS RFSSVSVARSAAGSG GLGRISSAGASFGSR SLYNLGGAKRVSING CGSSCRSGFGGRASN RFGVNSGFGYGGGVG GGFSGPSFPVCPPGG IQEVTVNQSLLTPLH LQIDPTIQRVRAEER EQIKTLNNKFASFID KVRFLEQQNKVLETK WALLQEQGSRTVRQN LEPLFDSYTSELRRQ LESITTERGRLEAEL RNMQDVVEDFKVRYE DEINKRTAAENEFVA LKKDVDAAYMNKVEL EAKVKSLPEEINFIH SVFDAELSQLQTQVG DTSVVLSMDNNRNLD LDSIIAEVKAQYEDI ANRSRAEAESWYQTK YEELQVTAGRHGDDL RNTKQEISEMNRMIQ RLRAEIDSVKKQCSS LQTAIADAEQRGELA LKDARAKLVDLEEAL QKAKQDMARLLREYQ ELMNIKLALDVEIAT YRKLLEGEECRLSGE GVSPVNISVVTSTLS SGYGSGSSIGGGNLG LGGGSGYSFTTSGGH SLGAGLGGSGFSATS NRGLGGSGSSVKFVS TTSSSQKSYTH
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue

Gene Name : KRT75 keratin 75 [ Homo sapiens ]
Official Symbol : KRT75
Synonyms : KRT75; keratin 75; keratin, type II cytoskeletal 75; K6HF; K75; CK-75; hK6hf; keratin-75; cytokeratin-75; type II keratin-18; cytokeratin type II; type II keratin-K6hf; type-II keratin Kb18; keratin-6 hair follicle; PFB; KB18;
Gene ID : 9119
mRNA Refseq : NM_004693
Protein Refseq : NP_004684
MIM : 609025
UniProt ID : O95678

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