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KRT83

Official Full Name

Keratin 83
Overview

Keratin 83, also known as KRT83, is a protein which humans is encoded by the KRT83 gene. The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB6, is found primarily in the hair cortex.
Synonyms

KRT83; keratin 83; hHb3; Basic Hair Keratin K83; HB3; Hb-3; KRTHB3; MGC141663; keratin, type II cuticular Hb3; K83; keratin-83; hair keratin K2.10; type-II keratin Kb23; keratin, hair, basic, 3; hard keratin, type II, 3; type II hair keratin Hb3.;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	KRT83-959HCL	Recombinant Human KRT83 cell lysate		Non		Inquiry
Human	KRT83-6100HF	Recombinant Full Length Human KRT83 Protein, GST-tagged	In Vitro Cell Free System	GST	493 amino acids	Inquiry
Human	KRT83-4832H	Recombinant Human KRT83 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Mouse	KRT83-8859M	Recombinant Mouse KRT83 Protein	Mammalian Cell	His		Inquiry
Mouse	KRT83-4944M-B	Recombinant Mouse KRT83 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	KRT83-4944M	Recombinant Mouse KRT83 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

KRT83 involved in several pathways and played different roles in them. We selected most pathways KRT83 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KRT83 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

KRT83 has several biochemical functions, for example, protein binding, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KRT83 itself. We selected most functions KRT83 had, and list some proteins which have the same functions with KRT83. You can find most of the proteins on our site.

Function	Related Protein
protein binding	ZMAT4;LHX9;MRPL12;C14orf166;RUFY1;TRPC6;EPC1;TMEM194;CD300LG
structural molecule activity	KRT13;SYNC;KRT34;LAD1;CLDN12;COPG;MAPK8IP2;MAP7D2A;EPB41L3A

KRT83 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KRT83 here. Most of them are supplied by our site. Hope this information will be useful for your research of KRT83.

KRT38; KRTAP10-7; KRTAP10-8; KRTAP10-9; KRT31; NOTCH2NL

Research Area

Rao, P; Lahat, G; et al. Angiosarcoma: A Tissue Microarray Study With Diagnostic Implications. AMERICAN JOURNAL OF DERMATOPATHOLOGY 35:432-437(2013).

Joosse, SA; Hannemann, J; et al. Changes in Keratin Expression during Metastatic Progression of Breast Cancer: Impact on the Detection of Circulating Tumor Cells. CLINICAL CANCER RESEARCH 18:993-1003(2012).