Recombinant Human KRT83 Protein, GST-tagged

• Cat.No.: KRT83-4832H
• Product Overview: Human KRT83 full-length ORF ( AAH69546.1, 1 a.a. - 493 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB6, is found primarily in the hair cortex. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 80.6 kDa
• AA Sequence: MTCGFNSIGCGFRPGNFSCVSACGP RPSRCCITAAPYRGISCYRGLTGGF GSHSVCGGFRAGSCGRSFGYRSGGV CGPSPPCITTVSVNESLLTPLNLEI DPNAQCVKQEEKEQIKSLNSRFAAF IDKVRFLEQQNKLLETKLQFYQNRE CCQSNLEPLFAGYIETLRREAECVE ADSGRLASELNHVQEVLEGYKKKYE EEVALRATAENEFVALKKDVDCAYL RKSDLEANVEALIQEIDFLRRLYEE EIRILQSHISDTSVVVKLDNSRDLN MDCIVAEIKAQYDDIATRSRAEAES WYRSKCEEMKATVIRHGETLRRTKE EINELNRMIQRLTAEVENAKCQNSK LEAAVAQSEQQGEAALSDARCKLAE LEGALQKAKQDMACLIREYQEVMNS KLGLDIEIATYRRLLEGEEQRLCEG VEAVNVCVSSSRGGVVCGDLCVSGS RPVTGSVCSAPCNGNLVVSTGLCKP CGQLNTTCGGGSCGQGRH
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: KRT83 keratin 83 [ Homo sapiens ]
• Official Symbol: KRT83
• Synonyms: KRT83; keratin 83; keratin, hair, basic, 3 , KRTHB3; keratin, type II cuticular Hb3; hard keratin type II; Hb 3; K83; hHb3; keratin-83; hair keratin K2.10; type-II keratin Kb23; keratin, hair, basic, 3; hard keratin, type II, 3; type II hair keratin Hb3; HB3; Hb-3; KRTHB3; MGC141663
• Gene ID: 3889
• mRNA Refseq: NM_002282
• Protein Refseq: NP_002273
• MIM: 602765
• UniProt ID: P78385