LGALS3BP

  • Official Full Name

    lectin, galactoside-binding, soluble, 3 binding protein

  • Overview

    The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.
  • Synonyms

    LGALS3BP; lectin, galactoside-binding, soluble, 3 binding protein; galectin-3-binding protein; 90K; BTBD17B; L3 antigen; Mac 2 binding protein; MAC 2 BP; serum protein 90K; MAC2BP; Tumor associated antigen 90K; 90K MAC 2 BP; Basement membrane autoantigen p105; Galectin 3 binding protein; Lectin galactoside binding soluble 3 binding protein; Lectin galactoside-binding soluble 3-binding protein; LG3BP_HUMAN; M2BP; Mac-2 BP; Mac-2-binding protein; Tumor-associated antigen 90K; MAC-2-BP;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Mammalian Cell
  • Mammalian cells
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
  • N
  • T7
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LGALS3BP-26801TH Recombinant Human LGALS3BP, T7 -tagged E.coli T7
Human LGALS3BP-156H Recombinant Human LGALS3BP Protein, His-tagged Mammalian cells His
Human LGALS3BP-1544H Recombinant Human LGALS3BP, T7-tagged E.coli T7
Human LGALS3BP-1771H Recombinant Human LGALS3BP protein, His & T7-tagged E.coli His/T7 Met24~Leu221 (Accession # Q08380)
Human LGALS3BP-4765HCL Recombinant Human LGALS3BP 293 Cell Lysate HEK293 N/A
Human LGALS3BP-3349H Recombinant Human LGALS3BP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human LGALS3BP-3349H-B Recombinant Human LGALS3BP Protein Pre-coupled Magnetic Beads HEK293
Human LGALS3BP-4437H Recombinant Human LGALS3BP Protein (Met24-Leu221), N-His tagged E.coli N-His Met24-Leu221
Mouse Lgals3bp-5676M Active Recombinant Mouse Lectin, Galactoside-Binding, Soluble, 3 Binding Protein, His-tagged Mammalian cells His
Mouse Lgals3bp-651M Active Recombinant Mouse Lgals3bp Protein, His-tagged Mammalian cells His Thr19-Val577
Mouse LGALS3BP-9063M Recombinant Mouse LGALS3BP Protein Mammalian Cell His
Mouse Lgals3bp-1772M Recombinant Mouse Lgals3bp protein, His & T7-tagged E.coli His/T7 Thr19~Val577 (Accession # Q07797)
Mouse LGALS3BP-5055M Recombinant Mouse LGALS3BP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Lgals3bp-5054M Recombinant Mouse Lgals3bp Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Lgals3bp-5056M Recombinant Mouse Lgals3bp Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Lgals3bp-5054M-B Recombinant Mouse Lgals3bp Protein Pre-coupled Magnetic Beads HEK293
Mouse Lgals3bp-5056M-B Recombinant Mouse Lgals3bp Protein Pre-coupled Magnetic Beads HEK293
Mouse LGALS3BP-5055M-B Recombinant Mouse LGALS3BP Protein Pre-coupled Magnetic Beads HEK293
Rat LGALS3BP-3388R Recombinant Rat LGALS3BP Protein Mammalian Cell His
Rat LGALS3BP-3044R Recombinant Rat LGALS3BP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat LGALS3BP-620R Recombinant Rat LGALS3BP Protein (19-574 aa), His-tagged E.coli His 19-574 aa
Rat LGALS3BP-3044R-B Recombinant Rat LGALS3BP Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

LGALS3BP involved in several pathways and played different roles in them. We selected most pathways LGALS3BP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LGALS3BP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

LGALS3BP has several biochemical functions, for example, scavenger receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LGALS3BP itself. We selected most functions LGALS3BP had, and list some proteins which have the same functions with LGALS3BP. You can find most of the proteins on our site.

Function Related Protein
scavenger receptor activityTMPRSS2;SCARA5;SCARF2;HHIPL1;TMPRSS3;CD163L1;TMPRSS13B;LOXL2;CD6

LGALS3BP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LGALS3BP here. Most of them are supplied by our site. Hope this information will be useful for your research of LGALS3BP.

Tubg1; Nup107; Mzt2; gag-pol; NFKB2; HSP90AB1; MAP3K8; Cbx1; RELA; MAP3K1; IKBKE; TRADD; Mzt1; Gorasp1

Research Area

Related articles

Stampolidis, P; Ullrich, A; et al. LGALS3BP, lectin galactoside-binding soluble 3 binding protein, promotes oncogenic cellular events impeded by antibody intervention. ONCOGENE 34:39-52(2015).
Traini, S; Piccolo, E; et al. Inhibition of Tumor Growth and Angiogenesis by SP-2, an Anti-Lectin, Galactoside-Binding Soluble 3 Binding Protein (LGALS3BP) Antibody. MOLECULAR CANCER THERAPEUTICS 13:916-925(2014).
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