Active Recombinant Mouse Lectin, Galactoside-Binding, Soluble, 3 Binding Protein, His-tagged

Cat.No. : Lgals3bp-5676M
Product Overview : Recombinant Mouse Lgals3bpprotein was expressed in Murine myeloma cell line with a C-terminal 6-Histag. Thr19-Val577.
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Cat. No. : Lgals3bp-5676M
Description : Lgals3bp, calledCyCAP in the mouse, is a secreted glycoprotein of the scavenger receptorcysteine-rich (SRCR) superfamily. Mouse Lgals3bp is generally considered theparalog of human Lgals3bp, which is also called MAC2 binding protein(MAC2BP), or 90 kDa tumor associated antigen (TAA90K or 90K). However, mouseLgals3bp binds cyclophilin C but not Galectin3 (formerly MAC2), while theopposite is true of human Lgals3bp. The 577 amino acid (aa), 77-95 kDa mouseLgals3bp contains an 18 aa signal sequence and four definitive domains.
Source : Mammalian cells
Form : Lyophilized from a0.2 μm filtered solution in MOPS, NaCl and Imidazole with trehalose.
N-terminalSequence : Thr19
Molecular Weight : 63.3 kDa
Activity : Measuredby its binding ability in a functional ELISA. When rmLgals3bp is coated at 1 μg/mL (100 μL/well), rhGalectin3 bindswith an apparent KD < 5 nM.
Endotoxin Level : <1.0 EUper 1 μg of the protein by the LAL method.
SDS-PAGE : 80-90kDa, reducing conditions.
Purity : >90%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution : 300μg/mL in PBS
Storage : Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months fromdate of receipt, -20 to -70°C as supplied. 1 month, 2 to 8 °C under sterileconditions after reconstitution. 3 months, -20 to -70°C under sterileconditions after reconstitution.
SDS-PAGE:
Gene Name : Lgals3bp lectin,galactoside-binding, soluble, 3 binding protein [ Mus musculus ]
Official Symbol : Lgals3bp
Synonyms : Lgals3bp;lectin, galactoside-binding, soluble, 3 binding protein; 90K; CyCAP; Ppicap;MAC-2BP; galectin-3-binding protein; mama; cyp-C-associated protein;peptidylprolyl isomerase C-associated protein; lectin galactoside-bindingsoluble 3-binding protein; Protein MAMA
Gene ID : 19039
mRNA Refseq : NM_011150
Protein Refseq : NP_035280
UniProt ID : Q07797
Chromosome Location : 11; 11 E
Function : protein binding;scavenger receptor activity

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