|Official Full Name||LIM homeobox 1|
|Background||This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor important for the development of the renal and urogenital systems. This gene is a candidate for Mayer-Rokitansky-Kuster-Hauser syndrome, a disorder characterized by anomalies in the female genital tract.|
|Synonyms||LHX1; LIM homeobox 1; LIM/homeobox protein Lhx1; LIM 1; LIM1; LIM homeobox protein 1; homeobox protein Lim-1; LIM-1; MGC126723; MGC138141|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
lhx1 involved in several pathways and played different roles in them. We selected most pathways lhx1 participated on our site, such as Neural Crest Differentiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with lhx1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Neural Crest Differentiation||MBP; TXLNB; LHX2; GBX2; HOXA1; PMP22; TFAP2A; HEY2; SOX5; PRTG|
lhx1 has several biochemical functions, for example, sequence-specific DNA binding, transcription corepressor activity, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by lhx1 itself. We selected most functions lhx1 had, and list some proteins which have the same functions with lhx1. You can find most of the proteins on our site.
|sequence-specific DNA binding||MAFK; NR4A2A; FOXJ2; SALL4; SMAD3; HOXC3A; NFE2L1B; HOXC13; HNF4G; HOXD4A|
|transcription corepressor activity||NEUROD2; FEV; JUNB; GPS2; DR1; KCNA3; NAB2; CSDA; PROX1; NANOG|
|transcription factor activity, sequence-specific DNA binding||SKINT8; HIF1AB; MSC; ZNF812; ZSCAN4C; ZNF354B; HIC1; PRDM1; RUNX1T1; NR1H4|
|zinc ion binding||FTR54; PCGF5; NR1D2A; AGTPBP1; CXXC5; BIRC5; OAS2; HDAC4; PDLIM5A; POLR2I|
lhx1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with lhx1 here. Most of them are supplied by our site. Hope this information will be useful for your research of lhx1.