Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

LRRN2

  • Official Full Name

    leucine rich repeat neuronal 2

  • Overview

    The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
  • Synonyms

    LRRN2; leucine rich repeat neuronal 2; leucine rich repeat neuronal 5 , LRRN5; leucine-rich repeat neuronal protein 2; fibronectin type III; immunoglobulin and leucine rich repeat domain 7; FIGLER7; GAC1; leucine rich and ankyrin repeats 1; LRANK1; Fibronectin type III immunoglobulin and leucine rich repeat domain 7; GAC 1; Glioma amplified on chromosome 1; Glioma amplified on chromosome 1 protein; Leucine rich repeat neuronal 5; Leucine rich repeat neuronal protein 2; Leucine rich repeat neuronal protein 5; LRANK 1; LRRN 2; LRRN 5; OTTHUMP00000034222; OTTHUMP00000035083; leucine-rich repeat neuronal protein 5; fibronectin type III, immunoglob; LRRN5;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LRRN2-29432TH Recombinant Human LRRN2, His-tagged E.coli His
Human LRRN2-4618HCL Recombinant Human LRRN2 293 Cell Lysate HEK293 N/A
Human LRRN2-4631H Recombinant Human LRRN2 Protein, GST-tagged Wheat Germ GST
Human LRRN2-6081HF Recombinant Full Length Human LRRN2 Protein, GST-tagged In Vitro Cell Free System GST 713 amino acids
Homo sapiens (Human) RFL5342HF Recombinant Full Length Human Leucine-Rich Repeat Neuronal Protein 2(Lrrn2) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (19-713)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • LRRN2 Related Articles

LRRN2 involved in several pathways and played different roles in them. We selected most pathways LRRN2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LRRN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

LRRN2 has several biochemical functions, for example, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LRRN2 itself. We selected most functions LRRN2 had, and list some proteins which have the same functions with LRRN2. You can find most of the proteins on our site.

Function Related Protein
receptor activityADCYAP1R1;NLGN3;HTR3A;GRIA4B;CD86;KLRC4-KLRK1;SEMA4D;ITGB1A;PAQR3A

LRRN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LRRN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of LRRN2.

NEUROD4

West, AB; Cowell, RM; et al. Differential LRRK2 Expression in the Cortex, Striatum, and Substantia Nigra in Transgenic and Nontransgenic Rodents. JOURNAL OF COMPARATIVE NEUROLOGY 522:2465-2480(2014).
Daher, JPL; Volpicelli-Daley, LA; et al. Abrogation of alpha-synuclein-mediated dopaminergic neurodegeneration in LRRK2-deficient rats. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:9289-9294(2014).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All LRRN2 Products

Required fields are marked with *

My Review for All LRRN2 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends