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LRTOMT

Official Full Name

leucine rich transmembrane and 0-methyltransferase domain containing
Overview

This gene encodes two different proteins. One is a leucine-rich transmembrane protein of unknown function while the other is an O-methyltransferase. Defects in the O-methyltransferase protein can cause nonsyndromic deafness. Several transcript variants encoding different isoforms of each protein have been found for this gene.
Synonyms

LRTOMT; leucine rich transmembrane and 0-methyltransferase domain containing; deafness, autosomal recessive 63 , DFNB63, leucine rich repeat containing 51 , LRRC51; leucine-rich repeat-containing protein 51; transmembrane O-methyltransferase; COMT2; tran;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Homo sapiens (Human)
Human
Macaca mulatta (Rhesus macaque)
Pan troglodytes (Chimpanzee)
Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi coquereli)
Rat
Rhesus Macaque
Zebrafish

Source

E.coli expression system
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Myc|DDK

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	LRTOMT-4622H	Recombinant Human LRTOMT Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	LRTOMT-971H	Recombinant Human LRTOMT Protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Human	LRTOMT-6113HF	Recombinant Full Length Human LRTOMT Protein, GST-tagged	In Vitro Cell Free System	GST	192 amino acids	Inquiry
Rat	LRTOMT-3492R	Recombinant Rat LRTOMT Protein	Mammalian Cell	His		Inquiry
Rat	LRTOMT-3148R	Recombinant Rat LRTOMT Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	LRTOMT-3148R-B	Recombinant Rat LRTOMT Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Homo sapiens (Human)	RFL36264HF	Recombinant Full Length Human Transmembrane O-Methyltransferase(Lrtomt) Protein, His-Tagged	E.coli expression system	His	Full Length (1-291)	Inquiry
Macaca mulatta (Rhesus macaque)	RFL9882MF	Recombinant Full Length Macaca Mulatta Transmembrane O-Methyltransferase(Lrtomt) Protein, His-Tagged	E.coli expression system	His	Full Length (1-296)	Inquiry
Pan troglodytes (Chimpanzee)	RFL17929PF	Recombinant Full Length Pan Troglodytes Transmembrane O-Methyltransferase(Lrtomt) Protein, His-Tagged	E.coli expression system	His	Full Length (1-291)	Inquiry
Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi coquereli)	RFL26121PF	Recombinant Full Length Propithecus Coquereli Transmembrane O-Methyltransferase(Lrtomt) Protein, His-Tagged	E.coli expression system	His	Full Length (1-274)	Inquiry
Rhesus Macaque	LRTOMT-2576R	Recombinant Rhesus monkey LRTOMT Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	LRTOMT-2396R	Recombinant Rhesus Macaque LRTOMT Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	LRTOMT-2396R-B	Recombinant Rhesus Macaque LRTOMT Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	LRTOMT-4593Z	Recombinant Zebrafish LRTOMT	Mammalian Cell	His		Inquiry
Chicken	LRTOMT-5433C	Recombinant Chicken LRTOMT	Mammalian Cell	His		Inquiry

LRTOMT Related Articles

LRTOMT involved in several pathways and played different roles in them. We selected most pathways LRTOMT participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LRTOMT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

LRTOMT has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by LRTOMT itself. We selected most functions LRTOMT had, and list some proteins which have the same functions with LRTOMT. You can find most of the proteins on our site.

Function	Related Protein

LRTOMT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LRTOMT here. Most of them are supplied by our site. Hope this information will be useful for your research of LRTOMT.

Riahi, Z; Bonnet, C; et al. Whole Exome Sequencing Identifies New Causative Mutations in Tunisian Families with Non-Syndromic Deafness. PLOS ONE 9:-(2014).

Charif, M; Bounaceur, S; et al. The c.242G > A mutation in LRTOMT gene is responsible for a high prevalence of deafness in the Moroccan population. MOLECULAR BIOLOGY REPORTS 39:11011-11016(2012).