Recombinant Human LRTOMT Protein, GST-tagged
Cat.No. : | LRTOMT-4622H |
Product Overview : | Human LRTOMT full-length ORF (BAG35968.1, 1 a.a. - 192 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene includes two transcript forms. The short form has one open reading frame (ORF), which encodes the leucine-rich repeats (LRR)-containing protein of unknown function. This protein is called LRTOMT1 or LRRC51. The long form has two alternative ORFs; the upstream ORF has the same translation start codon as used in the short form and the resulting transcript is a candidate for nonsense-mediated decay, and the downstream ORF encodes a different protein, which is a transmembrane catechol-O-methyltransferase and is called LRTOMT2, TOMT or COMT2. The COMT2 is essential for auditory and vestibular function. Defects in the COMT2 can cause nonsyndromic deafness. Alternatively spliced transcript variants from each transcript form have been found for this gene. [provided by RefSeq, Sep 2012] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 47.52 kDa |
AA Sequence : | MNKRDYMNTSVREPPLDYSFRSIHV IQDLVNEEPRTGLRPLKRSKSGKSL TQSLWLNNNVLNDLRDFNQVASQLL EHPENLAWIDLSFNDLTSIDPVLTT FFNLSVLYLHGNSIQRLGEVNKLAV LPRLRSLTLHGNPMEEEKGYRQYVL CTLSRITTFDFSGVTKADRTTAEVW KRMNIKPKKAWTKQNTL |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | LRTOMT leucine rich transmembrane and 0-methyltransferase domain containing [ Homo sapiens ] |
Official Symbol : | LRTOMT |
Synonyms : | LRTOMT; leucine rich transmembrane and 0-methyltransferase domain containing; deafness, autosomal recessive 63 , DFNB63, leucine rich repeat containing 51 , LRRC51; leucine-rich repeat-containing protein 51; transmembrane O-methyltransferase; COMT2; transmembrane O-methyltransferase; catechol O-methyltransferase 2; leucine rich repeat containing 51; DFNB63; LRRC51; LRTOMT1; LRTOMT2; FLJ52451; |
Gene ID : | 220074 |
mRNA Refseq : | NM_001145307 |
Protein Refseq : | NP_001138779 |
MIM : | 612414 |
UniProt ID : | Q8WZ04 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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