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LSP1

  • Official Full Name

    lymphocyte-specific protein 1

  • Overview

    This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils,;macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and;transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms.
  • Synonyms

    LSP1; lymphocyte-specific protein 1; WP34; 52 kDa phosphoprotein; 47 kDa actin binding protein; 47 kDa actin-binding protein; leukocyte-specific protein 1; lymphocyte-specific antigen WP34; leufactin (leukocyte F-actin binding protein); F-actin binding an;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • MYC
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LSP1-274H Recombinant Human LSP1 Mammalian Cell His
Human LSP1-585H Recombinant Human LSP1 Protein, His-tagged HEK293 His
Human LSP1-29147TH Recombinant Human LSP1 Wheat Germ N/A 99 amino acids
Human LSP1-9169HCL Recombinant Human LSP1 293 Cell Lysate HEK293 N/A
Human LSP1-4602H Recombinant Human LSP1 Protein, GST-tagged Wheat Germ GST
Human LSP1-2114H Recombinant Human LSP1 Protein (1-339 aa), GST-tagged E.coli GST 1-339 aa
Human LSP1-1717H Recombinant Human LSP1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human LSP1-3400H Recombinant Human LSP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human LSP1-3400H-B Recombinant Human LSP1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Lsp1-7902M Recombinant Mouse Lsp1 protein, His & T7-tagged E.coli His/T7 Ser126~Pro330 (Accession # P19973)
Mouse LSP1-9338M Recombinant Mouse LSP1 Protein Mammalian Cell His
Mouse LSP1-5231M-B Recombinant Mouse LSP1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Lsp1-1343M Recombinant Mouse Lsp1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse LSP1-5231M Recombinant Mouse LSP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Lsp1-7903R Recombinant Rat Lsp1 protein, His & T7-tagged E.coli His/T7 Ser127~Pro331 (Accession # Q4QQV6)
Chicken LSP1-5914C Recombinant Chicken LSP1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • LSP1 Related Articles

LSP1 involved in several pathways and played different roles in them. We selected most pathways LSP1 participated on our site, such as Tuberculosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with LSP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
TuberculosisITGB2L;IFNA6;RFXAP;ATP6AP1;BAX;CD209C;PPP3R1;CALM1;IRAK1

LSP1 has several biochemical functions, for example, actin binding, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LSP1 itself. We selected most functions LSP1 had, and list some proteins which have the same functions with LSP1. You can find most of the proteins on our site.

Function Related Protein
actin bindingMAEA;ACTN3A;CNN3B;FBXO25;EPB41;SSH2;MYO7B;CFL1;MYH1B
signal transducer activitySP110;GAB1;TAS2R103;GNG7;DRD7;DRD4A;YARS;OLFR498;PTH1RB

LSP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LSP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LSP1.

LYPD3; SNAI1; IL24; SCGB2A2; GREB1; THRSP; KLK6

Hossain, M; Qadri, SM; et al. ICAM-1-mediated leukocyte adhesion is critical for the activation of endothelial LSP1. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 304:C895-C904(2013).
Wu, Y; Zhan, LJ; et al. MAPKAPK2-mediated LSP1 phosphorylation and FMLP-induced neutrophil polarization. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 358:170-175(2007).
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