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Official Full Name melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
Background Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). An important group of antigens is coded by the MAGE family of genes. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues.
Synonyms MAGEA1; melanoma antigen family A, 1 (directs expression of antigen MZ2-E); MAGE1; melanoma-associated antigen 1; cancer/testis antigen family 1; member 1; CT1.1; melanoma antigen family A 1; melanoma antigen MAGE 1; melanoma associated antigen 1; melanoma associated antigen MZ2 E; MGC9326; antigen MZ2-E; MAGE-1 antigen; melanoma antigen MAGE-1; cancer/testis antigen 1.1; melanoma-associated antigen MZ2-E; cancer/testis antigen family 1, member 1
    • Species :
    • Human
    • Source :
    • E.coli
    • HEK293
    • Yeast
    • Tag :
    • FLAG
    • GST
    • His
    • T7
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MAGEA1-1450H Recombinant Human MAGEA1 Protein (1-309 aa), His-tagged Yeast His
    Human MAGEA1-157H Recombinant Human MAGEA1 E.coli N/A
    Human MAGEA1-1653H Recombinant Human MAGEA1 protein, His & T7-tagged E.coli His/T7
    Human MAGEA1-170H Recombinant Human MAGEA1 Protein, FLAG-tagged HEK293 FLAG
    Human MAGEA1-171H Recombinant Human MAGEA1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human MAGEA1-28505TH Recombinant Human MAGEA1 E.coli N/A
    Human MAGEA1-28H Recombinant Human MAGEA1 Protein, GST-tagged E.coli GST
    Human MAGEA1-4558HCL Recombinant Human MAGEA1 293 Cell Lysate HEK293 N/A

    magea1 involved in several pathways and played different roles in them. We selected most pathways magea1 participated on our site, such as Delta-Notch Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with magea1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Delta-Notch Signaling Pathway WDR12; RING1; ZFPM1; CNTN1B; APPA; ASCL1; CNTFR; YY1; TLE1; ASCL1A

    magea1 has several biochemical functions, for example, histone deacetylase binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by magea1 itself. We selected most functions magea1 had, and list some proteins which have the same functions with magea1. You can find most of the proteins on our site.

    Function Related Protein
    histone deacetylase binding TFAP4; HDAC1; HDAC5; CEBPB; MAGEA2B; TCF21; PKN1; TRAF6; CEBPA; WDTC1
    protein binding DDX19A; UBTD1; SNAP23; LCMT1; EIF4EA; SF3A1; NPDC1; COLQ; LTBP2; SLMAP

    magea1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with magea1 here. Most of them are supplied by our site. Hope this information will be useful for your research of magea1.


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