Recombinant Human MAGEA1 Protein (1-309 aa), His-tagged

• Cat.No.: MAGEA1-1450H
• Product Overview: Recombinant Human MAGEA1 Protein (1-309 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Cancer. Protein Description: Full Length.

Specification

• Description: May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in bryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
• Source: Yeast
• Species: Human
• Tag: His
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 36.3 kDa
• Protein length: 1-309 aa
• AA Sequence: MSLEQRSLHCKPEEALEAQQEALGL VCVQAATSSSSPLVLGTLEEVPTAG STDPPQSPQGASAFPTTINFTRQRQ PSEGSSSREEEGPSTSCILESLFRA VITKKVADLVGFLLLKYRAREPVTK AEMLESVIKNYKHCFPEIFGKASES LQLVFGIDVKEADPTGHSYVLVTCL GLSYDGLLGDNQIMPKTGFLIIVLV MIAMEGGHAPEEEIWEELSVMEVYD GREHSAYGEPRKLLTQDLVQEKYLE YRQVPDSDPARYEFLWGPRALAETS YVKVLEYVIKVSARVRFFFPSLREA ALREEEEGV
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: MAGEA1 melanoma antigen family A, 1 (directs expression of antigen MZ2-E) [ Homo sapiens ]
• Official Symbol: MAGEA1
• Synonyms: MAGEA1; MAGE1; member 1; CT1.1; MGC9326; antigen MZ2-E
• Gene ID: 4100
• mRNA Refseq: NM_004988
• Protein Refseq: NP_004979
• MIM: 300016
• UniProt ID: P43355