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MAGEA3

Official Full Name

melanoma antigen family A, 3
Overview

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
Synonyms

MAGEA3; melanoma antigen family A, 3; MAGE3; melanoma-associated antigen 3; antigen MZ2 D; cancer/testis antigen family 1; member 3; CT1.3; HIP8; HYPD; MAGE 3 antigen; melanoma associated antigen 3; MGC14613; MGC1461; MAGEA6; Melanoma antigen family A 3; antigen MZ2-D; MAGE-3 antigen; cancer/testis antigen 1.3; cancer/testis antigen family 1, member 3;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human

Source

E.coli
HEK293
HEK293T
Mammalian cells

Tag

Flag
His
His (Fc)
Avi
Myc
DDK
Myc|DDK
N/A
N
SUMO

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MAGEA3-2837H	Recombinant Human Melanoma Antigen Family A, 3, His-tagged	E.coli	His		Inquiry
Human	MAGEA3-28506TH	Recombinant Human MAGEA3, His-tagged	E.coli	His	314 amino acids	Inquiry
Human	MAGEA3-2126HCL	Recombinant Human MAGEA3 cell lysate		N/A		Inquiry
Human	MAGEA3-187H	Recombinant Human MAGEA3 Protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Human	MAGEA3-3199H	Recombinant Human MAGEA3 protein, His&Myc-tagged	E.coli	His&Myc	1-314aa	Inquiry
Human	MAGEA3-6580H	Recombinant Human MAGEA3 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	MAGEA3-1095H	Recombinant Human MAGEA3 Protein, His&SUMO-tagged	E.coli	N-His&SUMO	Met1-Glu314	Inquiry
Human	MAGEA3-391HFL	Recombinant Full Length Human MAGEA3 Protein, C-Flag-tagged	Mammalian cells	Flag		Inquiry
Human	MAGEA3-1340H	Recombinant Human MAGEA3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Human	MAGEA3-1340H-B	Recombinant Human MAGEA3 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
MAGEA3 Related Articles

MAGEA3 involved in several pathways and played different roles in them. We selected most pathways MAGEA3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MAGEA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

MAGEA3 has several biochemical functions, for example, caspase binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAGEA3 itself. We selected most functions MAGEA3 had, and list some proteins which have the same functions with MAGEA3. You can find most of the proteins on our site.

Function	Related Protein
caspase binding	FADD;MAGEA3;NOL3;BFAR
protein binding	PDIA2;DPH2;CCR5;MLST8;CAST;SSTR3;DPY30;ECE2;AVPR1A

MAGEA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAGEA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAGEA3.

TRIM28

Hemminger, JA; Toland, AE; et al. Expression of cancer-testis antigens MAGEA1, MAGEA3, ACRBP, PRAME, SSX2, and CTAG2 in myxoid and round cell liposarcoma. MODERN PATHOLOGY 27:1238-1245(2014).

Beard, RE; Abate-Daga, D; et al. Gene Expression Profiling using Nanostring Digital RNA Counting to Identify Potential Target Antigens for Melanoma Immunotherapy. CLINICAL CANCER RESEARCH 19:4941-4950(2013).