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Official Full Name melanoma antigen family A, 3
Background This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
Synonyms MAGEA3; melanoma antigen family A, 3; MAGE3; melanoma-associated antigen 3; antigen MZ2 D; cancer/testis antigen family 1; member 3; CT1.3; HIP8; HYPD; MAGE 3 antigen; melanoma associated antigen 3; MGC14613; MGC1461; MAGEA6; Melanoma antigen family A 3; antigen MZ2-D; MAGE-3 antigen; cancer/testis antigen 1.3; cancer/testis antigen family 1, member 3
    • Species :
    • Human
    • Source :
    • E.coli
    • HEK293
    • Tag :
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MAGEA3-187H Recombinant Human MAGEA3 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human MAGEA3-2126HCL Recombinant Human MAGEA3 cell lysate N/A
    Human MAGEA3-2837H Recombinant Human Melanoma Antigen Family A, 3, His-tagged E.coli His
    Human MAGEA3-28506TH Recombinant Human MAGEA3, His-tagged E.coli His

    magea3 involved in several pathways and played different roles in them. We selected most pathways magea3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with magea3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    magea3 has several biochemical functions, for example, caspase binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by magea3 itself. We selected most functions magea3 had, and list some proteins which have the same functions with magea3. You can find most of the proteins on our site.

    Function Related Protein
    caspase binding MAGEA3; NOL3; BFAR; FADD
    protein binding ASPSCR1; TRAF4; VIL1; PDIA2; KLB; OCIAD1; PPP4C; HIRIP3; PBK; CNOT10

    magea3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with magea3 here. Most of them are supplied by our site. Hope this information will be useful for your research of magea3.


    Hemminger, JA; Toland, AE; et al. Expression of cancer-testis antigens MAGEA1, MAGEA3, ACRBP, PRAME, SSX2, and CTAG2 in myxoid and round cell liposarcoma. MODERN PATHOLOGY 27:1238-1245(2014).
    Beard, RE; Abate-Daga, D; et al. Gene Expression Profiling using Nanostring Digital RNA Counting to Identify Potential Target Antigens for Melanoma Immunotherapy. CLINICAL CANCER RESEARCH 19:4941-4950(2013).

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