MAP1LC3C
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Official Full Name
microtubule-associated protein 1 light chain 3 gamma -
Overview
Autophagy is a highly regulated bulk degradation process that plays an important role in cellular maintenance and;development. MAP1LC3C is an ortholog of the yeast autophagosome protein Atg8 (He et al., 2003 (PubMed;12740394)). -
Synonyms
MAP1LC3C;microtubule-associated protein 1 light chain 3 gamma;microtubule-associated proteins 1A/1B light chain 3C;ATG8J;Autophagy related protein LC3 C;Autophagy related ubiquitin like modifier LC3 C;LC3 like protein 2;MAP1 light chain 3 like protein 2;MAP1 light chain 3 like protein 3;MAP1A/MAP1B LC3 C;Microtubule associated protein 1 light chain 3 gamma;Microtubule associated proteins 1A/1B light chain 3C;LC3-like protein 2;MAP1A/MAP1B light chain 3 C;autophagy-related protein LC3 C;MAP1 light chain 3-like protein 2;MAP1 light chain 3-like protein 3;autophagy-related ubiquitin-like modifier LC3 C;LC3C
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MAP1LC3C-731H | Recombinant Human MAP1LC3C protein, His-tagged | E. coli | Human | His | ||
| MAP1LC3C-10629Z | Recombinant Zebrafish MAP1LC3C | Mammalian Cells | Zebrafish | His |
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| MAP1LC3C-1053HCL | Recombinant Human MAP1LC3C cell lysate | Human | Non |
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| MAP1LC3C-2414H | Recombinant Human MAP1LC3C Protein, His-tagged | E.coli | Human | His | Met1-Gly126 |
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| MAP1LC3C-4914H | Recombinant Human MAP1LC3C protein, His-tagged | E.coli | Human | His | 1-126aa |
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| MAP1LC3C-7311H | Recombinant Human MAP1LC3C protein, His-tagged | E. coli | Human | His |
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Involved Pathway
MAP1LC3C involved in several pathways and played different roles in them. We selected most pathways MAP1LC3C participated on our site, such as Cellular responses to stress,Macroautophagy,Senescence and Autophagy, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAP1LC3C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Senescence and Autophagy | IL24,IGFBP7,ATG7,SLC39A3,IGFBP5,AMBRA1,RSL1D1,COL10A1,CREG1,LC3 |
| Macroautophagy | ATG9A,LC3,AMBRA1A,WDR45,WIPI2,GABARAP,GABARAPL2,WIPI1,UVRAG,MAP1LC3B |
| Cellular responses to stress | KDM6B,EGLN2,EEF1A1,TERF2,GABARAPL2,ST13,RNF2,TERF1,AGO3,RRAGA |
Protein Function
MAP1LC3C has several biochemical functions, for example, microtubule binding,protein binding,ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAP1LC3C itself. We selected most functions MAP1LC3C had, and list some proteins which have the same functions with MAP1LC3C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ubiquitin protein ligase binding | RPA2,VCL,PRKACA,UBE2NB,UBE2G1B,HIF1A,KCNQ3,CCDC50,ATXN3,TNFRSF14 |
| microtubule binding | MACF1,NUSAP1,ZFP207,SERPINB1A,KIF18B,KIFC1,MTAP4,KATNA1,GABARAPL1,KIF21A |
| protein binding | SELPLG,ZNF426,ZUFSP,SRMS,GCM1,ZFPM1,ARIH1,PYY,FOXD3,HPSE |
Interacting Protein
MAP1LC3C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAP1LC3C here. Most of them are supplied by our site. Hope this information will be useful for your research of MAP1LC3C.
SQSTM1;NBR1;WDFY3;ATG16L1
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References
- Zhang, LS; Zhang, J; et al. Autophagy in Pancreatic Acinar Cells in Caerulein-treated Mice: Immunolocalization of Related Proteins and Their Potential as Markers of Pancreatitis. TOXICOLOGIC PATHOLOGY 42:435-457(2014).
- Nicola, AM; Albuquerque, P; et al. Macrophage Autophagy in Immunity to Cryptococcus neoformans and Candida albicans. INFECTION AND IMMUNITY 80:3065-3076(2012).
- Ives, JH; Fung, S; et al. Microtubule-associated protein light chain 2 is a stargazin-AMPA receptor complex-interacting protein in vivo. JOURNAL OF BIOLOGICAL CHEMISTRY 279:31002-31009(2004).
