Map3k1 Protein

Map3k1

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Map3k1

Official Full Name mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
Background MEKK1 is member of the serine/threonine protein kinase family and is a target in the JNK and ERK pathways. Phosphorylation of MEKK1 works with other kinases to activate cellular responses to mitogenic and metabolic stimuli.
Synonyms MAP3K1; mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase; MEKK1, mitogen activated protein kinase kinase kinase 1; mitogen-activated protein kinase kinase kinase 1; MAPKKK1; MEKK; MEK kinase 1; MAP/ERK kinase kinase 1; MAPK/ERK kinase kinase 1; MEKK1; SRXY6; MEKK 1;
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Mammalian cells
    • Sf9 Insect Cell
    • Tag :
    • Flag
    • GST
    • His
    • His (Fc)-Avi
    • T7
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Rat Map3k1-665R Active Recombinant Rat Mitogen Activated Protein Kinase Kinase Kinase 1 E.coli N/A Inquiry
    Human MAP3K1-1037H Recombinant Human Mitogen-Activated Protein Kinase Kinase Kinase 1, GST-Tagged Sf9 Insect Cell GST Inquiry
    Human MAP3K1-1540H Recombinant Human MAP3K1 protein, His & T7-tagged E.coli His/T7 Inquiry
    Human MAP3K1-30190TH Recombinant Human MAP3K1 Sf9 Insect Cell N/A Inquiry
    Rat MAP3K1-3563R Recombinant Rat MAP3K1 Protein Mammalian Cell His Inquiry
    Human MAP3K1-1357H Recombinant Human MAP3K1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi Inquiry
    Human MAP3K1-1515HFL Recombinant Full Length Human MAP3K1 Protein, C-Flag-tagged Mammalian cells Flag Inquiry
    Mouse Map3k1-3204M Recombinant Mouse Map3k1 protein, His-tagged E.coli His Inquiry
    Rat MAP3K1-3219R Recombinant Rat MAP3K1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi Inquiry
    Human MAP3K1-2121H Recombinant Human MAP3K1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK Inquiry
    Human MAP3K1-393H Recombinant Human MAP3K1 Protein, MYC/DDK-tagged HEK293 Myc/DDK Inquiry
    Mouse Map3k1-3926M Recombinant Mouse Map3k1 Protein, Myc/DDK-tagged HEK293T Myc/DDK Inquiry

    Map3k1 involved in several pathways and played different roles in them. We selected most pathways Map3k1 participated on our site, such as MAPK signaling pathway, Ubiquitin mediated proteolysis, RIG-I-like receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Map3k1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway CACNA1C; MAPK12A; CACNA2D3; FGFR2; CACNG8; MINK1; FGF16; ZAK; CACNA2D2; CACNA1G
    Ubiquitin mediated proteolysis CBL; PARK2; FBXW8; FBXO2; SMURF2; FBXW11B; PIAS4B; ANAPC11; UBE2Z; CUL4B
    RIG-I-like receptor signaling pathway IFNA5; IFNA4; IKBKB; MAVS; TRAF6; TBKBP1; DAK; TANK; DHX58; FADD
    Neurotrophin signaling pathway RPS6KA2; RIPK2; IRAK1; SHC4; SHC3; MAP3K1; MATK; PTPN11; NGFRAP1; PSEN1
    GnRH signaling pathway MAP3K4; GNA11B; PRKACG; CAMK2G1; ADCY2B; PRKCD; ATF4B1; GNAS; CALM1A; GNRHR
    Hepatitis B PIK3CG; CASP9; IFNA7; IKBKB; TNF; IKBKG; IFN-a; TGFB1; IFNA10; TGFBR1
    HTLV-I infection WNT9A; NFATC1; WNT6; CRTC2; WNT10B; ANAPC7; FZD6; ATF3; HLA-DPA1; ANAPC11

    Map3k1 has several biochemical functions, for example, ATP binding, JUN kinase kinase kinase activity, MAP kinase kinase kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Map3k1 itself. We selected most functions Map3k1 had, and list some proteins which have the same functions with Map3k1. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding PIK3C2G; CAMK2D; MERTK; KIF3B; ATP2B1A; TTLL2; PCCB; AK3; PIM3; PRKG1A
    JUN kinase kinase kinase activity MAP3K11; MAP3K9; MAP3K10; ALPK2; MAP3K1
    MAP kinase kinase kinase activity MAP3K5; MAP3K6; YSK4; MAP3K13; MAP3K4; MAP3K3; BRAF; MAP3K15; EGFR; TAOK3
    protein binding ESR1; JAK2; SBDS; PLUNC; FOXK1; MOAP1; LENG1; RFC5; CLSTN1; PHYHIPL
    protein kinase activity TNNI3K; CASKA; DCLK1; IKBKB; BMPR1BB; NRBP2; RAF1B; PAK2; AURKC; NEK4
    protein kinase binding MAP2K3; PRKAG2; SMAD3; NCS1; BAD; USP37; LAT; KCNQ3; MAP3K5; AKAP7
    zinc ion binding TP53I3; MAP3K1; LIN28B; MT1F; CPXM2; PML; CSRP1B; ZPR1; ZDHHC3A; KDM5BB

    Map3k1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Map3k1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Map3k1.

    DCAF7; YWHAE; BRAF; MAP2K4; HSPA1L; TRAF2; ARRB2

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