Recombinant Mouse Map3k1 Protein, Myc/DDK-tagged

• Cat.No.: Map3k1-3926M
• Product Overview: Purified recombinant protein of mouse full-length mitogen-activated protein kinase kinase kinase 1 (Map3k1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Ubiquitous expression in spleen adult (RPKM 7.6), thymus adult (RPKM 6.2) and 28 other tissues.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 161.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Map3k1 mitogen-activated protein kinase kinase kinase 1 [ Mus musculus (house mouse) ]
• Official Symbol: Map3k1
• Synonyms: MAP3K1; mitogen-activated protein kinase kinase kinase 1; MEKK 1; MEK kinase 1; MAPK/ERK kinase kinase 1; mitogen activated protein kinase kinase kinase 1; Mekk; MEKK1; MAPKKK1
• Gene ID: 26401
• mRNA Refseq: NM_011945
• Protein Refseq: NP_036075
• UniProt ID: F8VQ72

Reviews

12/20/2020

The bands of proteins in Western Blotting experiments were very clear.

11/10/2020

The MAP3K1 protein is highly recommended for its exceptional performance in ELISA assays.

09/30/2017

Researchers can rely on the MAP3K1 protein to deliver precise results, enhancing the credibility and efficiency of their experiments.

Q&As

How is MAP3K1 protein expression measured in clinical settings?

MAP3K1 protein expression can be measured using immunohistochemistry (IHC) or Western blotting in clinical settings.

Are there any diseases associated with MAP3K1 protein mutations?

Yes, mutations in the MAP3K1 gene have been linked to several diseases, including breast cancer, lung cancer, and colon cancer.

What are the implications of MAP3K1 protein in drug resistance?

MAP3K1 protein has been implicated in the development of drug resistance in certain cancer types, highlighting its importance in personalized medicine and treatment response.

What are the potential diagnostic applications of MAP3K1 protein analysis?

MAP3K1 protein analysis can be used for diagnostic purposes to identify specific molecular subtypes of cancer and to predict disease prognosis.

How is MAP3K1 protein targeted in precision medicine approaches?

Precision medicine approaches may involve targeting MAP3K1 protein through specific inhibitors or monoclonal antibodies to inhibit its oncogenic activity.