| Cat.No. : |
Map3k1-665R
Optional Service: Optional requirements on this protein
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| Product Overview : |
Recombinant Rat Mitogen Activated Protein Kinase Kinase Kinase 1 is produced inEscherichia coli.MW= 42 kDa. |
| Description : |
MAP kinase is a serine/threonine kinase that is activated by MEK through a phosphorylation cascade. The cascade starts with extracellular signals transmitted by growth factor-regulated receptor tyrosine kinases or G-protein coupled receptors. Dually phosphorylated (Thr and Tyr) MAP kinase translocates from the cytoplasm to the nucleus, where it phosphorylates protein transcription factors, transducing extracellular signals into genomic responses, proliferation or differentiation. |
| Source : |
E. coli. |
| Purity : |
≥95% (SDS-PAGE). |
| Unit Definition : |
One unit of activated MAP kinase will transfer 1 nmole of phosphate from ATP to myelin basic protein per min at 30 °C. |
| Physical Form : |
Solution in 20 mM Tris, pH 7.5, 150 mM NaCl, 1 mM EGTA, 10% glycerol, 1 mM DTT, and 0.03% Brij. |
| Form : |
Buffered aqueous glycerol solution. |
| Activity : |
≥500 units/mg. |
| Legal Information : |
Brij is a registered trademark of Croda International PLC. |
| Storage : |
−70°C. Shipped in dry ice. |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
