Recombinant Human MAP3K1 protein, His & T7-tagged MAP3K1-1540H

Recombinant Human MAP3K1 protein, His & T7-tagged

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Recombinant Human MAP3K1 protein, His & T7-tagged

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Cat.No. : MAP3K1-1540H Optional Service: Optional requirements on this protein
Product Overview : Recombinant Human MAP3K1 aa. (Ile1307~Arg1509 (Accession # Q13233)) fused with N-terminal His & T7 tag was produced in E. coli cells.
Description : The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus.
Source : E. coli
Species : Human
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 26.1kDa.
Protein length : Ile1307~Arg1509 (Accession # Q13233)
Endotoxin : <1.0EU per 1µg (determined by the LAL method).
Purity : >95%
Characteristic : The isoelectric point is 9.2.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
SDS-PAGE :

Gene Name : MAP3K1 mitogen-activated protein kinase kinase kinase 1 [ Homo sapiens (human) ]
Official Symbol : MAP3K1
Synonyms : MEKK; MEKK1; SRXY6; MEKK 1; MAPKKK1; MAP/ERK kinase kinase 1; MAPK/ERK kinase kinase 1; MEK kinase 1; mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase; mitogen-activated protein kinase kinase kinase 1
Gene ID : 4214
mRNA Refseq : NM_005921.1
Protein Refseq : NP_005912.1
UniProt ID : Q13233
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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