Recombinant Human MAP3K1 Protein, MYC/DDK-tagged

• Cat.No.: MAP3K1-393H
• Product Overview: Recombinant human MAP3K1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus. [provided by RefSeq, Mar 2012].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 164.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: mitogen-activated protein kinase kinase kinase 1 [ Homo sapiens ]
• Official Symbol: MAP3K1
• Synonyms: MAPKKK1; MEKK; MEKK 1; MEKK1; SRXY6
• Gene ID: 4214
• mRNA Refseq: NM_005921.1
• Protein Refseq: NP_005912.1
• MIM: 600982
• UniProt ID: Q13233