MAP3K10 involved in several pathways and played different roles in them. We selected most pathways MAP3K10 participated on our site, such as Insulin Signaling, p38 MAPK signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAP3K10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
| Insulin Signaling |
MAPK4; MYO1C; FLOT1; MAP3K2; MAP4K1; SNAP25A; RRAD; RHOJ; MAPK6; INPP4AA |
| p38 MAPK signaling pathway |
GADD45G; MAP3K9; MAP3K10 |
MAP3K10 has several biochemical functions, for example, ATP binding, JUN kinase kinase kinase activity, bHLH transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAP3K10 itself. We selected most functions MAP3K10 had, and list some proteins which have the same functions with MAP3K10. You can find most of the proteins on our site.
| Function |
Related Protein |
| ATP binding |
KDRL; SBK3; INSR; MYLK; DNAJA3B; MCM8; IARS2; SMARCAD1; MCM9; NME2A |
| JUN kinase kinase kinase activity |
ALPK2; MAP3K11; MAP3K9; MAP3K1; MAP3K10 |
| bHLH transcription factor binding |
SOX9; PSMD9; TCF12; HAND1; FOXH1; TWIST1; RUNX2; SIRT1; BHLHE40; ASCL1 |
| protein homodimerization activity |
GSTM1; QPRT; RELA; TIMELESS; GSTM2; PDXK; PDGFB; HSD17B4; SLC16A1; Fzd4 |
| protein kinase activity |
CLK4B; RLN1; CDK17; PTK7A; SBK1; TRIM28; PKN1; PRKDC; ADRBK1; STK4 |
| protein serine/threonine kinase activity |
ULK1; CDK11B; DCLK2; CLK1; RIPK4; PRPF4B; TSSK5; NEK10; NEK7; CDC42BPA |
| transcription corepressor activity |
SRSF2; RELB; TGIF1; DR1; ZNF136; CCND1; DDX54; TFCP2L1; TBL1Y; ZNF593 |
MAP3K10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAP3K10 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAP3K10.
GARS; ABL2; MLK4
Aslani, F; Schuppe, HC; et al. Targeting high mobility group box protein 1 ameliorates testicular inflammation in experimental autoimmune orchitis. HUMAN REPRODUCTION 30:417-431(2015).
Dhande, I; Ma, WS; et al. Angiotensin AT(2) receptor stimulation is anti-inflammatory in lipopolysaccharide-activated THP-1 macrophages. HYPERTENSION RESEARCH 38:21-29(2015).
