• Official Full Name

    microtubule-associated protein 4

  • Background

    The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Synonyms

    MAP4; microtubule-associated protein 4; MAP-4; Mtap-4; AA407148;
    • Type:
    • Cell & Tissue Lysates
    • Recombinant Proteins
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • His
    • His (Fc)
    • Avi
    • His|GST
    • His|T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MAP4-4502HCL Recombinant Human MAP4 293 Cell Lysate HEK293 N/A
    Human MAP4-6806H Recombinant Human MAP4 protein, His & GST-tagged E.coli His/GST
    Human MAP4-29752TH Recombinant Human MAP4 Wheat Germ N/A
    Human MAP4-4503HCL Recombinant Human MAP4 293 Cell Lysate HEK293 N/A
    Mouse MAP4-5337M Recombinant Mouse MAP4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse Map4-6807M Recombinant Mouse Map4 protein, His-tagged E.coli His
    Mouse MTAP4-10169M Recombinant Mouse MTAP4 Protein Mammalian Cell His
    Mouse MAP4-5337M-B Recombinant Mouse MAP4 Protein Pre-coupled Magnetic Beads HEK293
    Rat MAP4-3224R Recombinant Rat MAP4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rat MAP4-3568R Recombinant Rat MAP4 Protein Mammalian Cell His
    Rat Map4-6808R Recombinant Rat Map4 protein, His & T7-tagged E.coli His/T7
    Rat MAP4-3224R-B Recombinant Rat MAP4 Protein Pre-coupled Magnetic Beads HEK293
    Rhesus Macaque MAP4-2490R-B Recombinant Rhesus Macaque MAP4 Protein Pre-coupled Magnetic Beads HEK293
    Rhesus Macaque MAP4-2490R Recombinant Rhesus Macaque MAP4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rhesus Macaque MAP4-2670R Recombinant Rhesus monkey MAP4 Protein, His-tagged Mammalian Cell His
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • MAP4 Related Articles

    MAP4 involved in several pathways and played different roles in them. We selected most pathways MAP4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MAP4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    MAP4 has several biochemical functions, for example, microtubule binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAP4 itself. We selected most functions MAP4 had, and list some proteins which have the same functions with MAP4. You can find most of the proteins on our site.

    Function Related Protein
    microtubule bindingVAPB;SKA1;SBDS;CLASP1;BCL2L11;PRC1A;MTAP6;CRIPT;NDE1
    poly(A) RNA bindingHIST1H4D;SLC16A3;SLC25A5;NMD3;NOC2L;RBM34;GRB2;NCOA5;AKAP8
    structural molecule activityLLGL1;COL15A1;CLDN7;KRT72-PS;KRT86;KRT93;CLDN2;SPRR3;VIML

    MAP4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAP4 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAP4.

    Csnk1d; NCK1; PLCG1; PIK3R1; FYCO1; LDLR; ENO2; GSK3B; TERF1; tktA; q7ard3_yerpe; pepP; hisD; POT1; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; ssrna_ug

    Zhang, LS; Miao, L; et al. Multiple antigen peptide mimetics containing gp41 membrane-proximal external region elicit broad neutralizing antibodies against human immunodeficiency virus type 1 in guinea pigs. JOURNAL OF PEPTIDE SCIENCE 19:491-498(2013).
    Du, T; La Fontaine, SL; et al. Investigating copper-regulated protein expression in Menkes fibroblasts using antibody microarrays. PROTEOMICS 8:1819-1831(2008).
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