|Official Full Name||MCF.2 cell line derived transforming sequence-like|
|Background||Guanine nucleotide exchange factor DBS is a protein that in humans is encoded by the MCF2L gene.|
|Synonyms||MCF2L; MCF.2 cell line derived transforming sequence-like; guanine nucleotide exchange factor DBS; ARHGEF14; DBS; KIAA0362; OST; DBLs big sister; MCF2 transforming sequence-like protein; FLJ12122|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
mcf2l involved in several pathways and played different roles in them. We selected most pathways mcf2l participated on our site, such as Cell death signalling via NRAGE, NRIF and NADE, G alpha (12/13) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with mcf2l were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Cell death signalling via NRAGE, NRIF and NADE||ITSN1; BCL2L11; OBSCN; ARHGEF18A; PLEKHG2; DCLRE1B; NET1; AATF; FGD2; ARHGEF3|
|G alpha (12/13) signalling events||ARHGEF3; RHOAE; FGD4A; ABR; ARHGEF1A; PLEKHG2; ADRA1D; ARHGEF18; OBSCN; TRIO|
|GPCR downstream signaling||NMUR1; EDN1; MCF2L; PDE10A; CHRM2; PROK2; GPR132; EDNRAB; S1PR3; PRKCHB|
|NRAGE signals death through JNK||DCLRE1B; ARHGEF18A; OBSCN; MCF2L; NET1; AKAP13; TIAM2; PLEKHG2; ARHGEF9; AATF|
|Neurotrophic factor-mediated Trk receptor signaling||MCF2L; RIT2; FAIM; RGS19; GIPC1; DYNLT1; RIT1|
|Regulation of CDC42 activity||BCAR3; MCF2L; ARHGAP17; SPATA13; ARHGEF25; RALBP1; DOCK10; ITSN2; DOCK9; DNMBP|
|Regulation of RhoA activity||ARHGEF3; ARHGEF10; ECT2; FARP1; ABR; ARAP1; ARHGEF18; ARHGEF15; ARHGAP9; DEF6|
|Rho GTPase cycle||MYO9B; MCF2L; ARHGAP18; GDI2; DEPDC1B; ARHGEF18A; ARHGAP19; ARHGAP32; AKAP13; FGD4A|
mcf2l has several biochemical functions, for example, 1-phosphatidylinositol binding, Rho guanyl-nucleotide exchange factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by mcf2l itself. We selected most functions mcf2l had, and list some proteins which have the same functions with mcf2l. You can find most of the proteins on our site.
|1-phosphatidylinositol binding||EPB41; SCIN; SNX9; PLEKHA2; CCDC167; WDFY3; SNX10; ZFYVE9; ZFYVE16; PICALMA|
|Rho guanyl-nucleotide exchange factor activity||NET1; FGD1; VAV3; ARHGEF11; ARHGEF3; ARHGEF9B; ARHGEF25; FGD6; ARHGEF28; MCF2L|
mcf2l has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with mcf2l here. Most of them are supplied by our site. Hope this information will be useful for your research of mcf2l.
SMAD2; AIMP2; YAE1D1; RABAC1; AGO1