MED10
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Official Full Name
Mediator complex subunit 10
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Overview
MED10 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II. -
Synonyms
MED10; mediator complex subunit 10; L6; NUT2; TRG20; mediator of RNA polymerase II transcription subunit 10; TRG-17; TRG-20; transformation-related gene 17 protein; HNUT2; MGC5309; transformation-related gene 20 protein; mediator of RNA polymerase II transcription, subunit 10; mediator of RNA polymerase II transcription, subunit 10 homolog (NUT2, S. cerevisiae); OTTHUMP00000220564;
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- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- MED10 Related Articles
MED10 involved in several pathways and played different roles in them. We selected most pathways MED10 participated on our site, such as Developmental Biology, Fatty acid, triacylglycerol, and ketone body metabolism, Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with MED10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Developmental Biology | JAK3;KCNQ2;MED19;RASGRP4;MARK3;COL9A3;SDCBP;ARPC1B;MED20 |
| Fatty acid, triacylglycerol, and ketone body metabolism | AGPAT6;MED31;CPT2;ACOT8;MED6;ACOT11A;YAP1;MED23;MTF1 |
| Gene Expression | ZNF614;ZNF691;HNRNPA0L;SPCS3;PTBP1B;NR2E1;TP53RK;ZNF771;SAP30 |
| Generic Transcription Pathway | PSTPIP2;NR2F6;ZNF184;ZNF302;FAM36A;ZNF498;ZFP1;ARHGEF38;ZNF559 |
| Metabolism | SURF1;CYP2A7;ACOT13;PNPLA8;DPYS;FMODA;NUDT18;CYP2S1;GNG13B |
| Metabolism of lipids and lipoproteins | MED9;G0S2;MED8;THEM5;ANKRD1;DHCR7;BCHE;MED21;MED10 |
| PPARA activates gene expression | TIAM2;SREBF2;MED22;MED19;CDK19;APOA5;MED26;MED29;MTF1 |
| Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | MED19;MED20;MED29;MED16;MED22;MED21;MED6;MED10;MTF1 |
MED10 has several biochemical functions, for example, RNA polymerase II transcription cofactor activity, protein binding, ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MED10 itself. We selected most functions MED10 had, and list some proteins which have the same functions with MED10. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II transcription cofactor activity | MED22;MED26;MED20;MED9;MED1;RBM14;MED8;MED4;CRSP7 |
| protein binding | OAS1;ZNF576;PDCD6;ZNF434;HEPACAM2;CCNDBP1;RAB43;FLT1;MMP2 |
| ubiquitin protein ligase activity | MED7;UBE2G1B;MED21;UBE2H;ITCHA;MSL2A;RFWD2;TOPORS;RNF144AA |
MED10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MED10 here. Most of them are supplied by our site. Hope this information will be useful for your research of MED10.
MED19; MED8; MED17
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