MED16
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Official Full Name
mediator complex subunit 16 -
Overview
Mediator of RNA polymerase II transcription subunit 16 is an enzyme that in humans is encoded by the MED16 gene. -
Synonyms
MED16;mediator complex subunit 16;THRAP5, thyroid hormone receptor associated protein 5;mediator of RNA polymerase II transcription subunit 16;DRIP92;TRAP95;DRIP 92;MED 16;THRAP 5;Thyroid hormone receptor associated protein 5;Thyroid hormone receptor associated protein complex 95 kDa component;Trap 95;Vitamin D3 receptor interacting protein complex component;thyroid hormone receptor-associated protein 5;thyroid hormone receptor-associated protein, 95-kD subunit;vitamin D3 receptor-interacting protein complex 92 kDa component;thyroid hormone receptor-assoc;THRAP5
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MED16-31175TH | Recombinant Human MED16, His-tagged | E.coli | Human | His | 663-751 a.a. |
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| MED16-7886Z | Recombinant Zebrafish MED16 | Mammalian Cells | Zebrafish | His |
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| MED16-11H | Recombinant Human MED16 protein, His-tagged | E.coli | Human | His | 1-350 aa |
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| MED16-4477H | Recombinant Human MED16 Protein, GST-tagged | Wheat Germ | Human | GST |
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| MED16-6211HF | Recombinant Full Length Human MED16 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 860 amino acids |
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Involved Pathway
MED16 involved in several pathways and played different roles in them. We selected most pathways MED16 participated on our site, such as Developmental Biology,Fatty acid, triacylglycerol, and ketone body metabolism,Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with MED16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Generic Transcription Pathway | NR2F6,ZNF189,COX6B1,ZNF729,ZNF480,ZNF726,ZNF529,ZNF383,ZNF460,ZFP28 |
| PPARA activates gene expression | GLIPR1,MED21,CDK19,CTGF,MED25,GRHL1,MED15,MED23,MED20,MED10 |
| Gene Expression | SUZ12B,ZNF669,ZNF561,EEF1G,HELZ2,NR2F1B,A1CF,ZNF615,METTL14,ZIM2 |
| Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | MTF1,MED23,MED15,MED21,MED9,MED6,MED25,MED26,MED19,MED22 |
| Fatty acid, triacylglycerol, and ketone body metabolism | ELOVL1A,MED6,ANKRD1,MED26,ACOT9.1,HELZ2,ACOT10,CCNC,ACAD11,MTF1 |
| Metabolism of lipids and lipoproteins | ACOT11A,CHAT,SREBF2,ACOT2,CYP2R1,Agmo,MED21,PNPLA8,AKR1C2,VAPB |
| Metabolism | PRKRA,SLC25A20,DGUOK,BRSK2,CRAT,GC,SLC4A1B,AHCY,CERS5,SLC25A1 |
| Developmental Biology | FGFR1B,CTNNA2,DUSP7,NADL1.1,TDGF1,EZRA,PAQR3A,EPHB4A,LIN28A,RASGRP4 |
Protein Function
MED16 has several biochemical functions, for example, catalytic activity,protein binding,receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MED16 itself. We selected most functions MED16 had, and list some proteins which have the same functions with MED16. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | NXT1,HIST1H2AI,SMC4,MYBBP1A,CST1,ELN,CYBB,MCM10,CACNB4,MIS18BP1 |
| transcription coactivator activity | ESR2,PRRX1,TDRD3,RARA,RIPK3,MAGED1,NFKB2,MAK,NCOA3,NR1I2 |
| receptor activity | TLR3,F2RL1.2,ANTXR2B,NOTCH1A,GFRA1A,CRLF1,SLC20A1,P2RY2,ADIPOR2,NLGN4Y |
| thyroid hormone receptor binding | GAS2L1,HMGN3,MED1,TAF11,TAF7,TRIP6,NUP62,MED24,NSD1,ZNHIT3 |
| vitamin D receptor binding | MED17,MED24,MED4,MED14,TAF11,SNW1,RXRA,TAF7,RUNX2B,MED30 |
| catalytic activity | LGI1A,CTHL,PGAM1A,HSD17B6,CKBB,PNP5B,DIP2BA,CKMB,ACSL1B,TPI1B |
| thyroid hormone receptor coactivator activity | NCOA2,ACTN2,MED1 |
| transcription cofactor activity | LDB1B,NRG1,TFB2M,NFE2L1,NFKBIZ,ZNF710,SLC26A3,PHF21A,TAF13,ANKRA2 |
Interacting Protein
MED16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MED16 here. Most of them are supplied by our site. Hope this information will be useful for your research of MED16.
MED10;MED19;CDK19;MED26;MED9;MED14;MED24;MED25
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