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MED16

Official Full Name

mediator complex subunit 16
Overview

Mediator of RNA polymerase II transcription subunit 16 is an enzyme that in humans is encoded by the MED16 gene.
Synonyms

MED16; mediator complex subunit 16; THRAP5, thyroid hormone receptor associated protein 5; mediator of RNA polymerase II transcription subunit 16; DRIP92; TRAP95; DRIP 92; MED 16; THRAP 5; Thyroid hormone receptor associated protein 5; Thyroid hormone receptor associated protein complex 95 kDa component; Trap 95; Vitamin D3 receptor interacting protein complex component; thyroid hormone receptor-associated protein 5; thyroid hormone receptor-associated protein, 95-kD subunit; vitamin D3 receptor-interacting protein complex 92 kDa component; thyroid hormone receptor-assoc; THRAP5;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MED16-31175TH	Recombinant Human MED16, His-tagged	E.coli	His		Inquiry
Human	MED16-4477H	Recombinant Human MED16 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	MED16-6211HF	Recombinant Full Length Human MED16 Protein, GST-tagged	In Vitro Cell Free System	GST	860 amino acids	Inquiry
Zebrafish	MED16-7886Z	Recombinant Zebrafish MED16	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

MED16 involved in several pathways and played different roles in them. We selected most pathways MED16 participated on our site, such as Developmental Biology, Fatty acid, triacylglycerol, and ketone body metabolism, Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with MED16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Developmental Biology	MEF2B;RHOAE;JAK3;DUSP4;SCN2A;CDON;DUSP1;RASGRP1;EFNA4
Fatty acid, triacylglycerol, and ketone body metabolism	MED10;SREBF2;MED15;Agmo;PPARGC1B;MED19;ANKRD1;SLC25A1;CPT1B
Gene Expression	TPRKB;ZNF668;ZNF773;TDRD1;ZNF557;EEF1E1;GTF3C4;NR0B2A;D1BWG0212E
Generic Transcription Pathway	ZNF274;ZNF664;ZNF70;ZNF486;LAMTOR1;ZNF561;ZNF133;ZNF649;MED6
Metabolism	OAZ2;NUBP2;CTRC;CHP;UST;OAZ1A;LYVE1;GDF1;PDK4
Metabolism of lipids and lipoproteins	CYP8B2;ACOT11;CYP24A1;MTP;GDF1;DPEP1;GRHL1;ACOT11B;PLBD1
PPARA activates gene expression	TIAM2;MED19;MED7;CDK19;MED29;MED25;MED8;MED9;APOA5
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)	MED31;MED10;MED23;MED20;MED25;GLIPR1;MED9;ANKRD1;GRHL1

MED16 has several biochemical functions, for example, catalytic activity, protein binding, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MED16 itself. We selected most functions MED16 had, and list some proteins which have the same functions with MED16. You can find most of the proteins on our site.

Function	Related Protein
catalytic activity	ACAA1A;PKMA;QDPRB1;ACSS2L;PNP5B;AOX3;PPM1BB;CWF19L1;PPM1NB
protein binding	CNBP;OGT;EIF3M;P2RY1;RTN4RL1;HELT;APC;C7orf59;UBE2L6
receptor activity	KLRG1;APLNR;CD200R4;BTLA;LILRB4;ANPEP;SIGLEC7;NR2C1;RPA1
thyroid hormone receptor binding	ZNHIT3;TRIP12;NCOA3;TAF11;GTF2B;TAF7;NSD1;MED13;MED16
thyroid hormone receptor coactivator activity	MED16;NCOA2;ACTN2;MED1
transcription coactivator activity	PSMD9;NR1H3;MTDH;THRAP3;RAP2C;MLL5;MED16;MYOD1;JUNB
transcription cofactor activity	MED1;TRIP13;MAX;PHF21B;PHF21A;MSX2;ZFP710;SUPT20H;ZFP667
vitamin D receptor binding	MED16;RUNX2B;MED24;SNW1;MED30;MED4;MED17;TAF7;RXRA

MED16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MED16 here. Most of them are supplied by our site. Hope this information will be useful for your research of MED16.

MED10; MED19; CDK19; MED26; MED9; MED14; MED24; MED25