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Official Full Name mediator complex subunit 20
Background MED20 is a subunit of the Mediator complex, a multiprotein coactivator of RNA transcription that interacts with;DNA-bound transcriptional activators, RNA polymerase II (see MIM 180660), and general initiation factors (Sato et al.,;2003 (PubMed 14576168)).
Synonyms MED20; mediator complex subunit 20; Trf (TATA binding protein related factor) proximal homolog (Drosophila) , TRFP; mediator of RNA polymerase II transcription subunit 20; DKFZp586D2223; PRO0213; TRF proximal protein homolog; TRFP; hTRFP; TRF-proximal protein homolog; Trf (TATA binding protein-related factor)-proximal homolog
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MED20-4389HCL Recombinant Human MED20 293 Cell Lysate HEK293 N/A
    Human MED20-7073H Recombinant HumanMED20, His-tagged E.coli His
    Mouse Med20-6637M Recombinant Mouse Med20 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse MED20-9692M Recombinant Mouse MED20 Protein Mammalian Cell His
    Rat MED20-3635R Recombinant Rat MED20 Protein Mammalian Cell His
    Cynomolgus Monkey MED20-684C Recombinant Cynomolgus MED20 Protein, His-tagged Mammalian Cell His
    Chicken MED20-1471C Recombinant Chicken MED20 Mammalian Cell His
    Zebrafish MED20-1013Z Recombinant Zebrafish MED20 Mammalian Cell His

    MED20 involved in several pathways and played different roles in them. We selected most pathways MED20 participated on our site, such as Developmental Biology, Fatty acid, triacylglycerol, and ketone body metabolism, Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with MED20 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Developmental Biology KBTBD7; LGI2A; DPYSL3; DUSP6; RASGRP1; ARHGEF28; TCF3B; KIF4; SPNA1; POU5F3
    Fatty acid, triacylglycerol, and ketone body metabolism ACOT9; SREBF2; ACOT9.2; SIN3B; ACOT13; THEM5; CPT2; CCNC; MED23; MED31
    Gene Expression EIF1AX; ZNF257; EHMT2; TTC6; ZNF566; ZNF285A; SUPT5H; CSTF1; HELZ2; NT5C3B
    Generic Transcription Pathway ZNF354A; RORAA; MED15; ZNF658; ZNF257; ZNF333; RARAA; ZNF234; ZNF544; ZNF19
    Metabolism B3GNT2A; KCNJ11; ST3GAL3A; KCNG4; ACY3.1; DCT; DPEP1; COQ7; CYP26A1; OSBP
    Metabolism of lipids and lipoproteins ACOT9.2; FAAH2; CYP11B1; DECR1; CHKA; ACOT13; ACOT11; CPNE7; ACOT8; MED10
    PPARA activates gene expression MED20; G0S2; MED16; MED15; MED8; MED21; MED26; MED23; CTGF; MED9
    Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) MED9; GLIPR1; MED31; MED21; MED26; CDK19; MED20; G0S2; MED7; MED6

    MED20 has several biochemical functions, for example, DNA-directed RNA polymerase activity, RNA polymerase II transcription cofactor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MED20 itself. We selected most functions MED20 had, and list some proteins which have the same functions with MED20. You can find most of the proteins on our site.

    Function Related Protein
    DNA-directed RNA polymerase activity POLR3C; CD3EAP; POLR2L; POLR2EB; POLR2GL; CRCP; RPAP1; POLR3G; POLR2I; PRIM2
    RNA polymerase II transcription cofactor activity MED24; MED13; MED14; TDG; MDT-19; CRSP7; MED4; MED19B; MED11; MED10
    protein binding CCDC155; ATP6V1D; PDHB; SERP1; RASSF2; ETL4; GLRA1; ABCA1; MBD4; ABI3
    transcription coactivator activity NCOA3; PRPF6; WWTR1; VGLL2; SP100; NR1I3; ZSCAN1; ELF3; TAF7; KAT2A
    ubiquitin protein ligase activity RNF144AB; UBE2V1; RNF144AA; MED23; RNF126; SIAH1A; HERC3; ANKIB1A; MDM2; PPIL2

    MED20 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MED20 here. Most of them are supplied by our site. Hope this information will be useful for your research of MED20.

    MED10; MED29; MED19; MED18; CDK19

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