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MED8

  • Official Full Name

    mediator complex subunit 8

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MED8-4378HCL Recombinant Human MED8 293 Cell Lysate HEK293 N/A
Human MED8-6252HF Recombinant Full Length Human MED8 Protein, GST-tagged In Vitro Cell Free System GST 212 amino acids
Human MED8-4465H Recombinant Human MED8 Protein, GST-tagged Wheat Germ GST
Mouse Med8-4022M Recombinant Mouse Med8 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Zebrafish MED8-11814Z Recombinant Zebrafish MED8 Mammalian Cell His
Chicken MED8-4954C Recombinant Chicken MED8 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

MED8 involved in several pathways and played different roles in them. We selected most pathways MED8 participated on our site, such as Developmental Biology, Fatty acid, triacylglycerol, and ketone body metabolism, Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with MED8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Developmental BiologyRGMA;EFNA1;ARPC2;CLTA;DPYSL5A;MED10;TCF4;TRPC5;SPTB
Fatty acid, triacylglycerol, and ketone body metabolismACOT9.2;MED19;ACOT11A;MED8;ACOT2;AGPAT6;STIL;DECR1;MED18
Gene ExpressionZNF485;ZNF224;KARS;ZNF254;D1BWG0212E;ZNF350;ZNF383;POP7;ZNF468
Generic Transcription PathwayZNF71;ZNF202;ZNF433;ZKSCAN1;NR5A1B;ZNF624;ZNF490;ESRRGA;ZNF613
Herpes simplex infectionPPP1CA;H2-Q10;IFIH1;SKP1;MHC2DEB;BLB1;HLA-DRB5;JAK2A;NFKBIAB
MetabolismSPTLC1;DHODH;FAAH2;HS3ST4;GNG13A;HIBADHA;MED25;CYP27B1;MMS19
Metabolism of lipids and lipoproteinsCHKA;AGPAT6;CDK19;CYP2AD3;CYP27B1;MED16;MED6;GPAT2;CHKB
PPARA activates gene expressionCTGF;APOA5;MED6;MED22;MED8;PLIN2;MED29;SREBF2;MED15

MED8 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II transcription cofactor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MED8 itself. We selected most functions MED8 had, and list some proteins which have the same functions with MED8. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II core promoter proximal region sequence-specific DNA bindingGLI2;JUN;YBX1;ISL1;NFIA;ZNF114;NKX6-1;IRF1;SFPI1
RNA polymerase II transcription cofactor activityMED19A;MED9;NKX2-5;CNOT2;MED20;MED13;THRAP3;PPARGC1A;MED22
protein bindingNAT10;HOXD12;LTF;DDI1;MRPL27;RSPH3;NFKBIL1;SH3PXD2B;UNC45A

MED8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MED8 here. Most of them are supplied by our site. Hope this information will be useful for your research of MED8.

MED10; MED19; MED29; CDK19; TCEB1

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