Recombinant Human MED8 Protein, GST-tagged

• Cat.No.: MED8-4465H
• Product Overview: Human MED8 full-length ORF ( NP_443109.1, 1 a.a. - 212 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. The product of this gene also interacts with elongins B and C, and CUL2 and RBX1, to reconstitute a ubiquitin ligase. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 49.1 kDa
• AA Sequence: MRQTEGRVPVFSHEVVPDHLRTKPD PEVEEQEKQLTTDAARIGADAAQKQ IQSLNKMCSNLLEKISKEERESESG GLRPNKQTFNPTDTNALVAAVAFGK GLSNWRPSGSSGPGQAGQPGAGTIL AGTSGLQQVQMAGAPSQQQPMLSGV QMAQAGQPGKMPSGIKTNIKSASMH PYQRPSCLGFILAIPLRRKVKKLLG QEGKKNAHLQLW
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MED8 mediator complex subunit 8 [ Homo sapiens ]
• Official Symbol: MED8
• Synonyms: MED8; mediator complex subunit 8; mediator of RNA polymerase II transcription, subunit 8 homolog (S. cerevisiae); mediator of RNA polymerase II transcription subunit 8; ARC32; MGC17544; MGC19641; activator-recruited cofactor 32 kDa component; mediator of RNA polymerase II transcription subunit MED8; mediator of RNA polymerase II transcription, subunit 8 homolog
• Gene ID: 112950
• mRNA Refseq: NM_052877
• Protein Refseq: NP_443109
• MIM: 607956
• UniProt ID: Q96G25