MGAT4A Protein


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Official Full Name mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
Background This gene encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme B, catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6(GlcNAc-beta-1,2-Man-alpha-1,3)Man-beta-1,4-GlcNAc-beta-1,4-GlcNAc-beta-1-Asn. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation.
Synonyms MGAT4A; mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A; mannosyl (alpha 1,3 ) glycoprotein beta 1,4 N acetylglucosaminyltransferase, isoenzyme A; alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferas
    • Species :
    • Bovine
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MGAT4A-2909H Recombinant Human MGAT4A protein, His-tagged E.coli His
    Human MGAT4A-4391H Recombinant Human MGAT4A protein, His-tagged E.coli His
    Human MGAT4A-4342HCL Recombinant Human MGAT4A 293 Cell Lysate HEK293 N/A
    Human MGAT4A-4366H Recombinant Human MGAT4A Protein, GST-tagged Wheat Germ GST
    Human MGAT4A-859H Recombinant Human MGAT4A, GST-tagged E.coli GST
    Mouse MGAT4A-9810M Recombinant Mouse MGAT4A Protein Mammalian Cell His
    Rat MGAT4A-3671R Recombinant Rat MGAT4A Protein Mammalian Cell His
    Cynomolgus Monkey MGAT4A-690C Recombinant Cynomolgus MGAT4A Protein, His-tagged Mammalian Cell His
    Rhesus Macaque MGAT4A-2760R Recombinant Rhesus monkey MGAT4A Protein, His-tagged Mammalian Cell His
    Bovine MGAT4A-3295B Recombinant Bovine MGAT4A, His-tagged E.Coli or Yeast His
    Chicken MGAT4A-2050C Recombinant Chicken MGAT4A Mammalian Cell His

    MGAT4A involved in several pathways and played different roles in them. We selected most pathways MGAT4A participated on our site, such as Asparagine N-linked glycosylation, Metabolic pathways, Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with MGAT4A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Asparagine N-linked glycosylation AREG; ST6GALNAC2; TRAPPC2L; LMAN2; TRAPPC5; MGAT4B; PPP6R1; MCFD2; SLC35A1; TRAPPC4
    Metabolic pathways DOLK; HAL; PLCD1A; PIK3C2A; GBE1; CYP4A14; SAT1; NME1; ZNRD1; udp
    Metabolism of proteins DAD1; TRAPPC6BL; APEH; TRAPPC9; KIFC3; EXOC5; NSFB; MLEC; EEF1B2; IGFBP1B
    N-Glycan antennae elongation MGAT4B; ST8SIA3; MGAT4A; ST8SIA2
    N-Glycan biosynthesis ALG10B; MGAT3; MGAT3A; ALG8; RPN2; DPM1; MGAT1A; RPN1; B4GALT2; DPM3
    N-glycan antennae elongation in the medial/trans-Golgi ST8SIA2; MGAT4A; MGAT4B; ST8SIA3
    Post-translational protein modification SEC23IP; SLC35A1; THSD1; GCNT3; ST8SIA3; MGAT4B; TRAPPC4; EID3; ATPBD4; ADAMTS20
    Transport to the Golgi and subsequent modification TRAPPC6B; TRAPPC2; TRAPPC9; TRAPPC1; TRAPPC10; CNIH2; CNIH3; PPP6R3; SCFD1; BET1

    MGAT4A has several biochemical functions, for example, alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MGAT4A itself. We selected most functions MGAT4A had, and list some proteins which have the same functions with MGAT4A. You can find most of the proteins on our site.

    Function Related Protein
    alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity MGAT4A; MGAT4B; MGAT4C; 4931440L10Rik
    metal ion binding ARSJ; RCV1; ZSCAN20; CHN2; CLIP1; NTHL1; BCO2; MPPED2; MICALL2; ITGA2

    MGAT4A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MGAT4A here. Most of them are supplied by our site. Hope this information will be useful for your research of MGAT4A.

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