MGAT4A

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MGAT4A

Official Full Name mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
Background This gene encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme B, catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6(GlcNAc-beta-1,2-Man-alpha-1,3)Man-beta-1,4-GlcNAc-beta-1,4-GlcNAc-beta-1-Asn. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation.
Synonyms MGAT4A; mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A; mannosyl (alpha 1,3 ) glycoprotein beta 1,4 N acetylglucosaminyltransferase, isoenzyme A; alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferas
    • Species :
    • Bovine
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MGAT4A-2909H Recombinant Human MGAT4A protein, His-tagged E.coli His
    Human MGAT4A-4391H Recombinant Human MGAT4A protein, His-tagged E.coli His
    Human MGAT4A-4342HCL Recombinant Human MGAT4A 293 Cell Lysate HEK293 N/A
    Human MGAT4A-4366H Recombinant Human MGAT4A Protein, GST-tagged Wheat Germ GST
    Human MGAT4A-859H Recombinant Human MGAT4A, GST-tagged E.coli GST
    Mouse MGAT4A-9810M Recombinant Mouse MGAT4A Protein Mammalian Cell His
    Rat MGAT4A-3671R Recombinant Rat MGAT4A Protein Mammalian Cell His
    Cynomolgus Monkey MGAT4A-690C Recombinant Cynomolgus MGAT4A Protein, His-tagged Mammalian Cell His
    Rhesus Macaque MGAT4A-2760R Recombinant Rhesus monkey MGAT4A Protein, His-tagged Mammalian Cell His
    Bovine MGAT4A-3295B Recombinant Bovine MGAT4A, His-tagged E.Coli or Yeast His
    Chicken MGAT4A-2050C Recombinant Chicken MGAT4A Mammalian Cell His

    MGAT4A involved in several pathways and played different roles in them. We selected most pathways MGAT4A participated on our site, such as Asparagine N-linked glycosylation, Metabolic pathways, Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with MGAT4A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Asparagine N-linked glycosylation LMAN2L; CTSC; CTSZ; MLEC; TRAPPC6A; NAPB; ALG10B; MPDU1B; SEC22C; ST3GAL3A
    Metabolic pathways NNT; PKM; ACAA2; ADH2-2; PCYT1AB; NMNAT3; UPRT; PGM3; PLA2G10; PIP5K1AA
    Metabolism of proteins SENP5; PREB; CST3; CXXC1; PHC2; INHBAA; MPDU1A; IGFBP4; ARSJ; SPON2
    N-Glycan antennae elongation MGAT4A; ST8SIA2; ST8SIA3; MGAT4B
    N-Glycan biosynthesis MGAT4A; MAN1A; MOGS; STT3B; B4GALT2; MGAT5B; ALG1; MAN1B1; ST6GAL1; DOLK
    N-glycan antennae elongation in the medial/trans-Golgi MGAT4A; ST8SIA2; MGAT4B; ST8SIA3
    Post-translational protein modification NSMCE1; CNIH3; UBA2; CBX4; TRAPPC10; YKT6; TRAPPC6B; ADAMTS1; MUC1; DPH3
    Transport to the Golgi and subsequent modification CNIH2; MGAT4A; TRAPPC2; MCFD2; TRAPPC2L; CNIH; TRAPPC6B; ANKRD28; PPP6R3; SCFD1

    MGAT4A has several biochemical functions, for example, alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MGAT4A itself. We selected most functions MGAT4A had, and list some proteins which have the same functions with MGAT4A. You can find most of the proteins on our site.

    Function Related Protein
    alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity 4931440L10Rik; MGAT4C; MGAT4A; MGAT4B
    metal ion binding CRYAB; ZNF311; TRIT1; ZFP804A; TRIM59; RIMS1; WBSCR17; HEPHL1A; KLF13; AGFG1A

    MGAT4A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MGAT4A here. Most of them are supplied by our site. Hope this information will be useful for your research of MGAT4A.

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