MGAT4A

  • Official Full Name

    mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A

  • Overview

    This gene encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme B, catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6(GlcNAc-beta-1,2-Man-alpha-1,3)Man-beta-1,4-GlcNAc-beta-1,4-GlcNAc-beta-1-Asn. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation.

  • Synonyms

    MGAT4A;mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A;mannosyl (alpha 1,3 ) glycoprotein beta 1,4 N acetylglucosaminyltransferase, isoenzyme A;alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferas

Recombinant Proteins

  • Human
  • Chicken
  • Rhesus macaque
  • Bovine
  • Rat
  • Cynomolgus
  • Mouse
  • E.coli
  • Mammalian Cells
  • E.Coli/Yeast
  • HEK293
  • Wheat Germ
  • GST
  • His
  • Non
  • GFP
  • Avi
  • Fc
  • Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
MGAT4A-859H Recombinant Human MGAT4A protein, GST-tagged E.coli Human GST
MGAT4A-2909H Recombinant Human MGAT4A protein, His-tagged E.coli Human His
MGAT4A-2050C Recombinant Chicken MGAT4A Mammalian Cells Chicken His
MGAT4A-2760R Recombinant Rhesus monkey MGAT4A Protein, His-tagged Mammalian Cells Rhesus macaque His
MGAT4A-3295B Recombinant Bovine MGAT4A, His-tagged E.Coli/Yeast Bovine His 535
MGAT4A-3671R Recombinant Rat MGAT4A Protein Mammalian Cells Rat His
MGAT4A-690C Recombinant Cynomolgus MGAT4A Protein, His-tagged Mammalian Cells Cynomolgus His
MGAT4A-9810M Recombinant Mouse MGAT4A Protein Mammalian Cells Mouse His
MGAT4A-4342HCL Recombinant Human MGAT4A 293 Cell Lysate HEK293 Human Non
MGAT4A-07H Recombinant Human MGAT4A Protein (AA 33-535), N-6×His/GFP tagged HEK293 Human GFP&His AA 33-535
MGAT4A-2581R Recombinant Rhesus Macaque MGAT4A Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
MGAT4A-2581R-B Recombinant Rhesus Macaque MGAT4A Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
MGAT4A-3327R Recombinant Rat MGAT4A Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
MGAT4A-3327R-B Recombinant Rat MGAT4A Protein Pre-coupled Magnetic Beads HEK293 Rat
MGAT4A-4366H Recombinant Human MGAT4A Protein, GST-tagged Wheat Germ Human GST
MGAT4A-436C Recombinant Cynomolgus Monkey MGAT4A Protein, His (Fc)-Avi-tagged HEK293 Cynomolgus Avi&Fc&His
MGAT4A-436C-B Recombinant Cynomolgus Monkey MGAT4A Protein Pre-coupled Magnetic Beads HEK293 Cynomolgus
MGAT4A-4391H Recombinant Human MGAT4A protein, His-tagged E.coli Human His 93-535aa
MGAT4A-5534M Recombinant Mouse MGAT4A Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
MGAT4A-5534M-B Recombinant Mouse MGAT4A Protein Pre-coupled Magnetic Beads HEK293 Mouse
MGAT4A-5935H Recombinant Human MGAT4A protein, His&Myc-tagged HEK293 Human His&Myc 93-535aa
RFL6902BF Recombinant Full Length Bovine Alpha-1,3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase A(Mgat4A) Protein, His-Tagged E.coli Bovine His Full L. Full Length (1-535)

    Involved Pathway

    MGAT4A involved in several pathways and played different roles in them. We selected most pathways MGAT4A participated on our site, such as Asparagine N-linked glycosylation,Metabolic pathways,Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with MGAT4A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    N-Glycan antennae elongation MGAT4B,ST8SIA3,ST8SIA2
    Asparagine N-linked glycosylation SEC24A,YKT6,MAN1B1,TRAPPC9,LMAN2,CTAGE5,MGAT4B,OS9,ANKRD28,MAN1A2
    Post-translational protein modification MPDU1A,MAN1B1,PPP6R3,MUCL1,DPH1,DPAGT1,DHPS,PHC3,GALNTL5,NSMCE2
    Metabolic pathways B3GNT2,SPHK2,ybaS,CYP51A1,PIGV,GCNT4,IDI1,PFKMA,DNMT3AB,ALPL
    Metabolism of proteins GPR120,MFGE8,PROCA,TGFBI,SMC5,SPCS3,THSD1,PAM16,FKBP14,MUCL1
    N-glycan antennae elongation in the medial/trans-Golgi ST8SIA2,MGAT4B,ST8SIA3
    N-Glycan biosynthesis B4GALT2,DOLK,MAN1A1,STT3A,DPM2,B4GALT1,MGAT4B,MGAT1A,TUSC3,ALG5
    Transport to the Golgi and subsequent modification ANKRD28,TRAPPC6B,LMAN2L,TRAPPC6BL,CNIH2,NAPB,CNIH,TRAPPC1,TRAPPC3,PPP6C

    Protein Function

    MGAT4A has several biochemical functions, for example, alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MGAT4A itself. We selected most functions MGAT4A had, and list some proteins which have the same functions with MGAT4A. You can find most of the proteins on our site.

    Function Related Protein
    alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity 4931440L10Rik,MGAT4B,MGAT4C
    metal ion binding ZFP280D,SMAD6,CAT,POLR2B,CYP46A1.4,STK32B,ZNF471,ARHGEF1A,TNKS2,THAP8

    Interacting Protein

    MGAT4A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MGAT4A here. Most of them are supplied by our site. Hope this information will be useful for your research of MGAT4A.

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