Recombinant Full Length Human MPO Protein, C-Flag-tagged

• Cat.No.: MPO-1300HFL
• Product Overview: Recombinant Full Length Human MPO Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 83.7 kDa
• AA Sequence: MGVPFFSSLRCMVDLGPCWAGGLTA EMKLLLALAGLLAILATPQPSEGAA PAVLGEVDTSLVLSSMEEAK QLVDKAYKERRESIKQRLRSGSASP MELLSYFKQPVAATRTAVRAADYLH VALDLLERKLRSLWRRPFNV TDVLTPAQLNVLSKSSGCAYQDVGV TCPEQDKYRTITGMCNNRRSPTLGA SNRAFVRWLPAEYEDGFSLP YGWTPGVKRNGFPVALARAVSNEIV RFPTDQLTPDQERSLMFMQWGQLLD HDLDFTPEPAARASFVTGVN CETSCVQQPPCFPLKIPPNDPRIKN QADCIPFFRSCPACPGSNITIRNQI NALTSFVDASMVYGSEEPLA RNLRNMSNQLGLLAVNQRFQDNGRA LLPFDNLHDDPCLLTNRSARIPCFL AGDTRSSEMPELTSMHTLLL REHNRLATELKSLNPRWDGERLYQE ARKIVGAMVQIITYRDYLPLVLGPT AMRKYLPTYRSYNDSVDPRI ANVFTNAFRYGHTLIQPFMFRLDNR YQPMEPNPRVPLSRVFFASWRVVLE GGIDPILRGLMATPAKLNRQ NQIAVDEIRERLFEQVMRIGLDLPA LNMQRSRDHGLPGYNAWRRFCGLPQ PETVGQLGTVLRNLKLARKL MEQYGTPNNIDIWMGGVSEPLKRKG RVGPLLACIIGTQFRKLRDGDRFWW ENEGVFSMQQRQALAQISLP
  RIICDNTGITTVSKNNIFMSNSYPR DFVNCSTLPALNLASWREASTRTRP LEQKLISEEDLAANDILDYKDDDDK V
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome

Gene Information

• Gene Name: MPO myeloperoxidase [ Homo sapiens (human) ]
• Official Symbol: MPO
• Synonyms: Myeloperoxidase
• Gene ID: 4353
• mRNA Refseq: NM_000250.2
• Protein Refseq: NP_000241.1
• MIM: 606989
• UniProt ID: P05164