Mrpl44

Official Full Name

mitochondrial ribosomal protein L44
Overview

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
Synonyms

MRPL44; L44MT; COXPD16; MRP-L44; mitochondrial ribosomal protein L44; 39S ribosomal protein L44, mitochondrial; NP_075066.1; EC 3.1.26.-;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Zebrafish

Source

E.coli
HEK293
Human Cell
In Vitro Cell Free System
Insect Cell
Mammalian Cell
Wheat Germ

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MRPL44-1007H	Recombinant Human MRPL44, His-tagged	E.coli	His	1-295aa	$319 / 25μg
Human	MRPL44-1095H	Recombinant Human MRPL44	Mammalian Cell	His		Inquiry
Human	MRPL44-339H	Recombinant Human MRPL44, His-tagged	Insect Cell	His	Met1-Ser332	Inquiry
Human	MRPL44-001HCL	Recombinant Human MRPL44 cell lysate	Human Cell	Non		Inquiry
Human	MRPL44-6425HF	Recombinant Full Length Human MRPL44 Protein, GST-tagged	In Vitro Cell Free System	GST	332 amino acids	Inquiry
Human	MRPL44-5588H	Recombinant Human MRPL44 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	MRPL44-3518H	Recombinant Human MRPL44 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Human	MRPL44-3518H-B	Recombinant Human MRPL44 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	MRPL44-10071M	Recombinant Mouse MRPL44 Protein	Mammalian Cell	His		Inquiry
Mouse	MRPL44-5704M-B	Recombinant Mouse MRPL44 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	MRPL44-5704M	Recombinant Mouse MRPL44 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Zebrafish	MRPL44-3340Z	Recombinant Zebrafish MRPL44	Mammalian Cell	His		Inquiry
Chicken	MRPL44-4818C	Recombinant Chicken MRPL44	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

Mrpl44 involved in several pathways and played different roles in them. We selected most pathways Mrpl44 participated on our site, such as Mitochondrial translation, Mitochondrial translation elongation, Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with Mrpl44 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Mitochondrial translation	MRPL49;MTIF3;MRPL28;MRPS27;MRPL54;MRPS31;MRPS30;MRPS35;GFM2
Mitochondrial translation elongation	ICT1;MRPL42;PTCD3;MRPL51;MRPL10;TUFM;MRPL47;MRPL53;MRPL39
Mitochondrial translation initiation	MRPS30;MRPS31;MRPL55;MRPL50;PTCD3;MRPL40;MRPL48;MRPS34;DAP3
Mitochondrial translation termination	PTCD3;MRPL52;MRPL47;MRPL53;MRPL55;MRPS22;ICT1;MRPL40;MRPS23
Organelle biogenesis and maintenance	TTBK2;CLUAP1;SCLT1;OST4;B9D1;MRPL51;DYNLL2A;MRPL53;C10orf2

Mrpl44 has several biochemical functions, for example, poly(A) RNA binding, protein binding, ribonuclease III activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Mrpl44 itself. We selected most functions Mrpl44 had, and list some proteins which have the same functions with Mrpl44. You can find most of the proteins on our site.

Function	Related Protein
poly(A) RNA binding	NONO;CCT3;HLA-A;SF3B2;APOBEC3F;PPIE;THUMPD1;GRB2;TRMT1L
protein binding	MCM2;POLDIP3;LRP5;NUP153;MX2;PMEPA1;PPIE;SCOC;TBC1D16
ribonuclease III activity	DICER1;BARHL1;DROSHA;AGFG1A;MRPL44;RNASEN

Mrpl44 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Mrpl44 here. Most of them are supplied by our site. Hope this information will be useful for your research of Mrpl44.

ABI2; VIM; SETDB1; IMMT; ARRB2; NFKBIL1; PPAP2C; PTN; SHC1; PI4KA; DGKE; ZNF235; NGEF; CEP70; ITFG1