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MRPL45

Official Full Name

mitochondrial ribosomal protein L45
Overview

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 2p and 17q.
Synonyms

MRPL45; mitochondrial ribosomal protein L45; 39S ribosomal protein L45, mitochondrial; MGC11321; L45mt; MRP-L45;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	MRPL45-1096H	Recombinant Human MRPL45	Mammalian Cell	His	Inquiry
Human	MRPL45-3519H-B	Recombinant Human MRPL45 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Human	MRPL45-3519H	Recombinant Human MRPL45 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Zebrafish	MRPL45-10636Z	Recombinant Zebrafish MRPL45	Mammalian Cell	His	Inquiry
Chicken	MRPL45-4116C	Recombinant Chicken MRPL45	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein

MRPL45 involved in several pathways and played different roles in them. We selected most pathways MRPL45 participated on our site, such as Mitochondrial translation, Mitochondrial translation elongation, Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL45 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Mitochondrial translation	MRPL40;GFM2;CHCHD1;MRPL38;PTCD3;TUFM;MRPS33;MRPL39;MRPL54
Mitochondrial translation elongation	MRPL28;MRPL10;MRPS28;MRPL40;MRPL46;MRPL3;MRPS22;MRPS33;MRPS24
Mitochondrial translation initiation	MTIF3;PTCD3;MRPL53;MRPL28;MRPL55;DAP3;MRPL51;ICT1;MRPL52
Mitochondrial translation termination	MRPL28;MRPS34;PTCD3;MRPS22;MRPS36;MRPL3;CHCHD1;MRPL42;MRPL39
Organelle biogenesis and maintenance	MRPS22;UNC119B;BBS1;TTC21B;TRAF3IP1;NPHP4;MRPS23;TTC30A2;IFT80

MRPL45 has several biochemical functions, for example, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL45 itself. We selected most functions MRPL45 had, and list some proteins which have the same functions with MRPL45. You can find most of the proteins on our site.

Function	Related Protein
poly(A) RNA binding	ALDH18A1;EIF2S1A;ZFP622;MRPS15;HIST1H4A;MRTO4;RPS4Y1;TWF2;ATP5C1
protein binding	HEPACAM2;NRXN1;C14orf166;HHEX;TAF1D;JAM3;TYRO3;KL;SCNN1G

MRPL45 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL45 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL45.

TRIM23; G3BP1; KBTBD7; C1qbp; NCAPD3; Nup188; Rpl35; MRPL50; Pip4k2c; ESR2; MRPL9; MRPL1; Dctn5