MRPL45

  • Official Full Name

    mitochondrial ribosomal protein L45

  • Overview

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 2p and 17q.
  • Synonyms

    MRPL45; mitochondrial ribosomal protein L45; 39S ribosomal protein L45, mitochondrial; MGC11321; L45mt; MRP-L45;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MRPL45-1096H Recombinant Human MRPL45 Mammalian Cell His
Human MRPL45-3519H-B Recombinant Human MRPL45 Protein Pre-coupled Magnetic Beads HEK293
Human MRPL45-3519H Recombinant Human MRPL45 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish MRPL45-10636Z Recombinant Zebrafish MRPL45 Mammalian Cell His
Chicken MRPL45-4116C Recombinant Chicken MRPL45 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

MRPL45 involved in several pathways and played different roles in them. We selected most pathways MRPL45 participated on our site, such as Mitochondrial translation, Mitochondrial translation elongation, Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL45 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Mitochondrial translationMTIF3;MRPL10;ICT1;MRPL53;MRPL51;MRPS22;MRPL40;MRPL48;GFM2
Mitochondrial translation elongationMRPS35;MRPS27;MRPL40;MRPL10;CHCHD1;MRPL44;MRPL49;MRPS33;TUFM
Mitochondrial translation initiationMRPS35;ICT1;CHCHD1;MRPS23;MRPL28;MRPL47;MRPL40;MRPL53;DAP3
Mitochondrial translation terminationMTRF1L;MRPS34;MRPL51;CHCHD1;MRPL52;DAP3;MRPS26;MRPL10;MRPL37
Organelle biogenesis and maintenanceBBS7;PPRC1;TRAF3IP1;MRPS22;MRPL55;IFT52;BBS2;KIFAP3B;RP2

MRPL45 has several biochemical functions, for example, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL45 itself. We selected most functions MRPL45 had, and list some proteins which have the same functions with MRPL45. You can find most of the proteins on our site.

Function Related Protein
poly(A) RNA bindingCCAR1;CELF1;RPF1;SLC16A3;PPIB;TRUB2;MCAT;SRP68;KPNA2
protein bindingERGIC2;PAICS;ACAA2;C16orf59;IQSEC3;NAA11;DHX15;MRFAP1;ZCCHC7

MRPL45 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL45 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL45.

TRIM23; G3BP1; KBTBD7; C1qbp; NCAPD3; Nup188; Rpl35; MRPL50; Pip4k2c; ESR2; MRPL9; MRPL1; Dctn5

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