MRPL50

  • Official Full Name

    mitochondrial ribosomal protein L50

  • Overview

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q.

  • Synonyms

    MRPL50;mitochondrial ribosomal protein L50;39S ribosomal protein L50, mitochondrial;FLJ20493;mitochondrial 39S ribosomal protein L50;MRP L50;L50mt;MRP-L50

Recombinant Proteins

  • Human
  • Chicken
  • Rhesus macaque
  • Mammalian Cells
  • HEK293
  • Wheat Germ
  • In Vitro Cell Free System
  • His
  • Non
  • Avi
  • Fc
  • GST
Cat.# Product name Source (Host) Species Tag Protein Length Price
MRPL50-1097H Recombinant Human MRPL50 Mammalian Cells Human His
MRPL50-1720C Recombinant Chicken MRPL50 Mammalian Cells Chicken His
MRPL50-2849R Recombinant Rhesus monkey MRPL50 Protein, His-tagged Mammalian Cells Rhesus macaque His
MRPL50-4159HCL Recombinant Human MRPL50 293 Cell Lysate HEK293 Human Non
MRPL50-2669R Recombinant Rhesus Macaque MRPL50 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
MRPL50-2669R-B Recombinant Rhesus Macaque MRPL50 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
MRPL50-3520H Recombinant Human MRPL50 Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
MRPL50-3520H-B Recombinant Human MRPL50 Protein Pre-coupled Magnetic Beads HEK293 Human
MRPL50-5594H Recombinant Human MRPL50 Protein, GST-tagged Wheat Germ Human GST
MRPL50-6440HF Recombinant Full Length Human MRPL50 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 158 amino acids

    Involved Pathway

    MRPL50 involved in several pathways and played different roles in them. We selected most pathways MRPL50 participated on our site, such as Mitochondrial translation,Mitochondrial translation elongation,Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Organelle biogenesis and maintenance MRPS33,GADD45GIP1,WDR19,TRIP11,TCTN3,MRPL53,TUFM,MRPL39,IFT22,TMEM216
    Mitochondrial translation elongation MRPL55,MRPS30,MRPS22,MRPL53,PTCD3,MRPL42,DAP3,MRPL28,MRPL38,MRPL51
    Mitochondrial translation initiation MRPL38,ICT1,MRPS27,MRPL51,MRPL53,MRPL42,MRPL37,MRPL40,CHCHD1,MRPL44
    Mitochondrial translation GADD45GIP1,MRPS30,AURKAIP1,TUFM,ICT1,MRPL40,MRPL41,MRPL46,MRPS28,DAP3
    Mitochondrial translation termination MRPS33,MRPL40,MRPS26,MRPL52,MRPL45,MRPL3,GADD45GIP1,GFM2,MRPS22,MRPL44

    Protein Function

    MRPL50 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL50 itself. We selected most functions MRPL50 had, and list some proteins which have the same functions with MRPL50. You can find most of the proteins on our site.

    Function Related Protein

    Interacting Protein

    MRPL50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL50 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL50.

    MRPL43;b4dln1_human;MRPL27;ATP5J2-PTCD1;MRPL42;ICT1;MRPL4;XRCC2;SYNCRIP;MRPL33;PCF11;TBC1D8;TRUB2;MRPL3;MRPL19;MRPL12;CORO7;MRPS35;MRPS6;HNRNPU

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