MRPL50
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Official Full Name
mitochondrial ribosomal protein L50
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Overview
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q. -
Synonyms
MRPL50; mitochondrial ribosomal protein L50; 39S ribosomal protein L50, mitochondrial; FLJ20493; mitochondrial 39S ribosomal protein L50; MRP L50; L50mt; MRP-L50;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Rhesus Macaque
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- Fc
- Avi
- Non
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | MRPL50-1097H | Recombinant Human MRPL50 | Mammalian Cell | His |
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| Human | MRPL50-4159HCL | Recombinant Human MRPL50 293 Cell Lysate | HEK293 | Non |
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| Human | MRPL50-5594H | Recombinant Human MRPL50 Protein, GST-tagged | Wheat Germ | GST |
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| Human | MRPL50-3520H-B | Recombinant Human MRPL50 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Human | MRPL50-6440HF | Recombinant Full Length Human MRPL50 Protein, GST-tagged | In Vitro Cell Free System | GST | 158 amino acids |
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| Human | MRPL50-3520H | Recombinant Human MRPL50 Protein, His (Fc)-Avi-tagged | HEK293 | His&Fc&Avi |
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| Rhesus Macaque | MRPL50-2849R | Recombinant Rhesus monkey MRPL50 Protein, His-tagged | Mammalian Cell | His |
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| Rhesus Macaque | MRPL50-2669R | Recombinant Rhesus Macaque MRPL50 Protein, His (Fc)-Avi-tagged | HEK293 | His&Fc&Avi |
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| Rhesus Macaque | MRPL50-2669R-B | Recombinant Rhesus Macaque MRPL50 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Chicken | MRPL50-1720C | Recombinant Chicken MRPL50 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
MRPL50 involved in several pathways and played different roles in them. We selected most pathways MRPL50 participated on our site, such as Mitochondrial translation, Mitochondrial translation elongation, Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Mitochondrial translation | MRPL3;GADD45GIP1;MRRF;ICT1;MTRF1L;MRPL10;MRPS23;MRPL45;MRPL39 |
| Mitochondrial translation elongation | TSFM;MRPS30;MRPS24;MRPL28;MRPS34;MRPS28;MRPL47;MRPL50;MRPS26 |
| Mitochondrial translation initiation | MRPL39;MRPL37;MRPS36;GADD45GIP1;MRPS24;MRPL54;MRPL28;MRPL42;MTFMT |
| Mitochondrial translation termination | MRPS30;MRPL39;MRPS35;MTRF1L;MRPS28;MRPL53;AURKAIP1;MRPS31;MRPS26 |
| Organelle biogenesis and maintenance | TTC30B;RAB3IP;IFT74;MRPL48;DYNLRB1;BBS1;ARF4A;NPHP4;IFT43 |
MRPL50 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL50 itself. We selected most functions MRPL50 had, and list some proteins which have the same functions with MRPL50. You can find most of the proteins on our site.
| Function | Related Protein |
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MRPL50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL50 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL50.
MRPL43; b4dln1_human; MRPL27; ATP5J2-PTCD1; MRPL42; ICT1; MRPL4; XRCC2; SYNCRIP; MRPL33; PCF11; TBC1D8; TRUB2; MRPL3; MRPL19; MRPL12; CORO7; MRPS35; MRPS6; HNRNPU
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