MTA2

  • Official Full Name

    metastasis associated 1 family, member 2

  • Overview

    MTA1 (metastasis associated gene 1) was identified in a differential screening of a cDNA library of metastatic and nonmetastatic adenocarcinoma cell lines (1), and was subsequently found to be an integral member of the nucleosome remodeling and deacetylat

  • Synonyms

    MTA2;metastasis associated 1 family, member 2;metastasis associated gene family, member 2 , MTA1L1;metastasis-associated protein MTA2;MTA1 L1;MTA1-L1 protein;metastasis-associated 1-like 1;metastasis-associated protein 2;metastasis -associated gen

Recombinant Proteins

  • Human
  • Mouse
  • Zebrafish
  • Rhesus macaque
  • E.coli
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • GST
  • His
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
MTA2-1071H Recombinant Human MTA2, GST-tagged E.coli Human GST 1-350aa
MTA2-294H Recombinant Human MTA2 Protein, His-tagged E.coli Human His Met1~Cys394
MTA2-10162M Recombinant Mouse MTA2 Protein Mammalian Cells Mouse His
MTA2-12725Z Recombinant Zebrafish MTA2 Mammalian Cells Zebrafish His
MTA2-26H Recombinant Human MTA2 protein, GST-tagged Wheat Germ Human GST 521-620 a.a.
MTA2-2890R Recombinant Rhesus monkey MTA2 Protein, His-tagged Mammalian Cells Rhesus macaque His
MTA2-2710R Recombinant Rhesus Macaque MTA2 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
MTA2-2710R-B Recombinant Rhesus Macaque MTA2 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
MTA2-5298H Recombinant Human MTA2 Protein (Met1-Cys394), N-His tagged E.coli Human His Met1-Cys394
MTA2-5763M Recombinant Mouse MTA2 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
MTA2-5763M-B Recombinant Mouse MTA2 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    MTA2 involved in several pathways and played different roles in them. We selected most pathways MTA2 participated on our site, such as Chromatin modifying enzymes,Chromatin organization,EGFR1 Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MTA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chromatin organization DNMT3A,SUZ12B,MSL2B,SUZ12,PADI4,KDM4D,KDM5D,TADA2B,PBRM1,MORF4L2
    Gene Expression CPSF4,DDX20,COX14,DHX9,DNMT1,LAMTOR1,ZNF223,AIMP1,ZNF671,NR0B1
    HDACs deacetylate histones CHD4A,GATAD2B,MTA1,BRMS1,MTA3,GATAD2AB,KDM1A,CHD4,ANO9A,ARID4A
    RNA Polymerase I Transcription Initiation CHD4,CHD4A,GATAD2B,MBD3B,MTA3,MBD3,GATAD2A,UBTF,RRN3,GATAD2AB
    RNA Polymerase I Promoter Clearance UBTF,EFCAB11,MBD3A,TAF1C,CHD4A,TAF1D,GATAD2AB,GATAD2A,MBD3,CHD4
    Chromatin modifying enzymes RUVBL2,WDR77,ATXN7,ING5,ELP2,TADA2B,SAP18,PADI3,GATAD2AB,PRDM16
    EGFR1 Signaling Pathway STXBP1A,RALBP1,CEBPA,SH2D3C,TNK2,KRT17,REPS2,RALBB,PITPNA,REPS1
    RNA Polymerase I Transcription GATAD2AB,MBD3B,TAF1B,MBD3,MBD3A,GATAD2B,GATAD2A,CBX3,MTA1,UBTF

    Protein Function

    MTA2 has several biochemical functions, for example, contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding,contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding,RNA polymerase II repressing transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MTA2 itself. We selected most functions MTA2 had, and list some proteins which have the same functions with MTA2. You can find most of the proteins on our site.

    Function Related Protein
    contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding SMARCC2,SMARCE1,ACTB,SMARCC1,SMARCB1,HDAC2,CHD4,MBD3,SMARCA4,ACTL6A
    protein binding PSMD9,PES1,DAG1,COX6B2,FAM110C,CRHBP,FKBPL,EN1,PIP4K2B,HCK
    RNA polymerase II transcription factor binding GATA2B,GATA1,GATA3,GSC,ATF4,ZFPM1,TAL1,ZFPM2,SMAD4,GATA1A
    contributes_to nucleosomal DNA binding SMARCC1,HDAC2,SMARCE1,HDAC1,SMARCA4,SMARCC2,RBBP4,MBD3,ACTL6A,ACTB
    transcription factor activity, transcription factor binding PER2,ASCL1B,LDB2A,LDB2B,CRY1,CRY2,NEUROG1,ASCL1,FOXO1,HIF1A
    histone deacetylase activity HDAC9B,HDAC7,SIRT1,HDAC5,NACC2,HDAC4,HDAC3,ATXN3L,HDAC6,HDAC1
    contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding GATAD2B,CHD4,RBBP4,SMARCA4,HDAC1,MBD3,SMARCE1,SMARCC1,ACTL6A,ACTB
    RNA polymerase II repressing transcription factor binding MIXL1,BBS5,BBS4,BBS7,HDAC1,DMAP1,TCERG1,BBS2,TCF7L2,GTF2A2
    transcription factor activity, sequence-specific DNA binding NANOG,PITX2,FOXC1A,ZSCAN23,RERE,NFIL3-2,NR1H4,CLOCKA,IRF1A,SOX11A

    Interacting Protein

    MTA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MTA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MTA2.

    HDAC1;HDAC2;MBD3;PARK7

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