NCOR1

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NCOR1

Official Full Name nuclear receptor corepressor 1
Background The most well characterized nuclear receptor corepressors are SMRT (silencing mediator for retinoic acid and thyroid hormone receptors) and its close paralog NCoR1 (nuclear receptor corepressor). NCoR1 functions to transcriptionally silence various unliga
Synonyms NCOR1; nuclear receptor corepressor 1; nuclear receptor co repressor 1; hCIT529I10; hN CoR; KIAA1047; MGC104216; N CoR; thyroid hormone and retinoic acid receptor associated corepressor 1; TRAC1; nuclear receptor co-repressor 1; thyroid hormone- and reti
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • Insect Cell
    • Mammalian Cell
    • Sf21 Insect Cell
    • Tag :
    • Flag
    • GST
    • His
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human NCOR1-16H Recombinant Human NCOR1/HDAC3 Protein, GST-tagged Insect Cell GST
    Human NCOR1-1705H Recombinant Human NCOR1 protein, His & T7-tagged E.coli His/T7
    Human NCOR1-28430TH Recombinant Human NCOR1, FLAG-tagged Flag
    Human NCOR1-8484H Recombinant Human NCOR1, His-tagged Sf21 Insect Cell His
    Mouse Ncor1-1706M Recombinant Mouse Ncor1 protein, His & T7-tagged E.coli His/T7
    Zebrafish NCOR1-10610Z Recombinant Zebrafish NCOR1 Mammalian Cell His

    NCOR1 involved in several pathways and played different roles in them. We selected most pathways NCOR1 participated on our site, such as Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with NCOR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Thyroid hormone signaling pathway GSK3B; PFKP; MAPK1; TSC2; PIK3R2; CASP9; ATP1B1; PIK3CD; PIK3CG; PDPK1
    Transcriptional misregulation in cancer ZBTB17; Itgam&Itgb2; IL1R2; MEIS1; IGFBP3; CD40; TGFBR2; MMP9; PAX7; PML

    NCOR1 has several biochemical functions, for example, RNA polymerase II activating transcription factor binding, histone deacetylase binding, histone deacetylase regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NCOR1 itself. We selected most functions NCOR1 had, and list some proteins which have the same functions with NCOR1. You can find most of the proteins on our site.

    Function Related Protein
    RNA polymerase II activating transcription factor binding T; LDB1; NEUROD1; EP300; MAD2L2; HIPK2; TP53BP1; TBX3; RB1; DUSP26
    histone deacetylase binding PRDM1; ZNF703; DDX20; HDAC3; DHX36; TOP2B; HEY2; BRMS1L; MYOCD; MEF2A
    histone deacetylase regulator activity NCOR1; TRP53; TP53; MAPK8
    ligand-dependent nuclear receptor binding ISL1; PPARGC1A; C1D; ARID1A; NCOR2; BAZ2A; SLC30A9; PROX1; SMARCE1; NCOA2
    nuclear hormone receptor binding NCOA3; MED1; ACTN4; CRX; TCF7L2; MYOD1; SMARCD3; EP300; NRIP1; BUD31
    protein binding MARVELD2; DIXDC1; CLPX; C5orf20; CHD; DPM1; TET2; CACNA1SB; ZDHHC13; SYT17
    retinoid X receptor binding NCOA1; NR4A2; NR0B2; NR1H4; HMGA1-RS1; NRIP1; HMGA1; MED25; FUS; NR1H2
    sequence-specific DNA binding ATF5A; BCL11B; NLRP3; DLX3; NR2F5; EMX3; BCL2; LHX1B; FOXN2B; OTX1B
    thyroid hormone receptor binding NUP62; GTF2B; HMGN3; OASL; FUS; MED30; MED12; TRIP12; TAF7; TRIP6
    transcription corepressor activity MXI1; SKOR1A; AES; SKI; ALX1; SIRT6; HIRA; YY1; PPP1R13L; PAWR
    transcription factor activity, sequence-specific DNA binding DMRT3A; RARAA; ATF7A; ZBTB48; HOXB2A; TAF4B; HDAC1; ZNF213; FOXP3; EOMESB
    transcription regulatory region DNA binding TAL1; CALCOCO1; RREB1; SALL4; MSX2; STAT3; NR5A2; HDAC1; HNF1A; SERPINB1A

    NCOR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NCOR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NCOR1.

    HDAC3; RARA; SKI; TRIM28; SMARCA4; SMARCB1; DHX30

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