ndel1 Protein, nudE nuclear distribution E homolog (A. nidulans)-like 1

ndel1

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ndel1

Official Full Name nudE nuclear distribution E homolog (A. nidulans)-like 1
Background This gene encodes a thiol-activated peptidase that is phosphorylated in M phase of the cell cycle. Phosphorylation regulates the cell cycle-dependent distribution of this protein, with a fraction of the protein bound strongly to centrosomes in interphase and localized to mitotic spindles in early M phase. Overall, this protein plays a role in nervous system development. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Synonyms NDEL1; nudE nuclear distribution E homolog (A. nidulans)-like 1; nudE nuclear distribution gene E homolog (A. nidulans) like 1; nuclear distribution protein nudE-like 1; MITAP1; NUDEL; protein Nudel; endooligopeptidase A; mitosin-associated protein 1; mit
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human NDEL1-2116H Recombinant Human NDEL1 Protein (1-345 aa), GST-tagged E.coli GST
    Human NDEL1-3936HCL Recombinant Human NDEL1 293 Cell Lysate HEK293 N/A
    Human NDEL1-3937HCL Recombinant Human NDEL1 293 Cell Lysate HEK293 N/A
    Mouse NDEL1-10495M Recombinant Mouse NDEL1 Protein Mammalian Cell His
    Rat NDEL1-3927R Recombinant Rat NDEL1 Protein Mammalian Cell His
    Chicken NDEL1-2399C Recombinant Chicken NDEL1 Mammalian Cell His

    ndel1 involved in several pathways and played different roles in them. We selected most pathways ndel1 participated on our site, such as Aurora A signaling, Cell Cycle, Cell Cycle, Mitotic, which may be useful for your reference. Also, other proteins which involved in the same pathway with ndel1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Aurora A signaling TPX2; OAZ1; AURKB; AURKAIP1; TACC1; CENPA; NDEL1; TDRD7; TACC3; GADD45A
    Cell Cycle CEP164; CCNA2; ANAPC4; CDC14AB; RAD9B; NDE1; RNF168; ABL1; MAPRE1A; SMC3
    Cell Cycle, Mitotic NIPBL; CENPN; ERCC6L; CSNK2A2; FGFR1OP; NIPBLA; MLF1IP; PHF8; TUBGCP4; CETN2
    Lissencephaly gene (LIS1) in neuronal migration and development MAP1B; NUDC; DCX; LRPAP1; DAB1; NDEL1; VLDLR; DYNLT1; KATNA1
    M Phase CENPO; CENPE; NCAPH; INCENP; SETB; PANE1; CTDNEP1; CENPK; KNTC1; NDC80
    Mitotic Anaphase RANGAP1B; CENPL; CCDC99; CDCA5; PDS5B; VRK2; LEMD3; CENPQ; B9D2; PANE1
    Mitotic Metaphase and Anaphase INCENP; MLF1IP; CENPE; CCDC99; AHCTF1; NSL1; NDEL1A; VRK2; SGOL2; CENPH
    Mitotic Prometaphase NUF2; CENPI; NCAPD2; CLIP1; PDS5B; CDCA8; NDEL1B; SKA2; CENPC1; SPC25

    ndel1 has several biochemical functions, for example, alpha-tubulin binding, beta-tubulin binding, microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ndel1 itself. We selected most functions ndel1 had, and list some proteins which have the same functions with ndel1. You can find most of the proteins on our site.

    Function Related Protein
    alpha-tubulin binding ARL8B; TRPV4; CAV3; BBS4; PROL1; HDAC6; WASH; ARL8A; SPAST; RACGAP1
    beta-tubulin binding RANBP10; VAPB; IFT74; ADNP; PIFO; SLC6A2; GABARAP; HTT; PACRG; ARL8A
    microtubule binding GABARAPL2; SBDS; EML2; KIF27; NEFH; REEP4; DCX; MAP2; LRPPRC; LC3
    oligopeptidase activity NDEL1
    protein binding ZWILCH; MRPL15; DERL1; INO80E; ZNF747; TMEM174; SCNN1D; STX19; ADD1; OAS3

    ndel1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ndel1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ndel1.

    CENPF; DISC1; TRIM27

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