Recombinant Human NDEL1 Protein (1-345 aa), GST-tagged
Cat.No. : | NDEL1-2116H |
Product Overview : | Recombinant Human NDEL1 Protein (1-345 aa) is produced by E. coli expression system. This protein is fused with a GST tag at the N-terminal. Research Area: Neuroscience. Protein Description: Full Length of BC026101. |
- Specification
- Gene Information
- Related Products
Description : | Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome. Also positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the centripetal motion of secretory vesicles and the coupling of the nucleus and centrosome. Also required during brain development for the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Plays a role, together with DISC1, in the regulation of neurite outgrowth. Required for mitosis in some cell types but appears to be dispensible for mitosis in cortical neuronal progenitors, which instead requires NDE1. Facilitates the polymerization of neurofilaments from the individual subunits NEFH and NEFL. |
Source : | E. coli |
Species : | Human |
Tag : | GST |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 65.4 kDa |
Protein length : | 1-345 aa |
AA Sequence : | MDGEDIPDFSSLKEETAYWKELSLK YKQSFQEARDELVEFQEGSRELEAE LEAQLVQAEQRNRDLQADNQRLKYE VEALKEKLEHQYAQSYKQVSVLEDD LSQTRAIKEQLHKYVRELEQANDDL ERAKRATIVSLEDFEQRLNQAIERN AFLESELDEKESLLVSVQRLKDEAR DLRQELAVRERQQEVTRKSAPSSPT LDCEKMDSAVQASLSLPATPVGKGT ENTFPSPKAIPNGFGTSPLTPSARI SALNIVGDLLRKVGALESKLAACRN FAKDQASRKSYISGNVNCGVLNGNG TKFSRSGHTSFFDKGAVNGFDTAPP PPGLGSSRPSSAPGMLPLSV |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA will be sent along with the products. Please refer to it for detailed information. |
Gene Name : | NDEL1 nudE nuclear distribution E homolog (A. nidulans)-like 1 [ Homo sapiens ] |
Official Symbol : | NDEL1 |
Synonyms : | NDEL1; MITAP1; NUDEL; protein Nudel; EOPA; DKFZp451M0318; |
Gene ID : | 81565 |
mRNA Refseq : | NM_001025579 |
Protein Refseq : | NP_001020750 |
MIM : | 607538 |
UniProt ID : | Q9GZM8 |
Products Types
◆ Recombinant Protein | ||
NDEL1-5951M | Recombinant Mouse NDEL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
NDEL1-3585R | Recombinant Rat NDEL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ndel1-4321M | Recombinant Mouse Ndel1 Protein, Myc/DDK-tagged | +Inquiry |
NDEL1-3927R | Recombinant Rat NDEL1 Protein | +Inquiry |
NDEL1-2399C | Recombinant Chicken NDEL1 | +Inquiry |
◆ Lysates | ||
NDEL1-3937HCL | Recombinant Human NDEL1 293 Cell Lysate | +Inquiry |
NDEL1-3936HCL | Recombinant Human NDEL1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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