ndrg4 Protein, NDRG family member 4


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Official Full Name NDRG family member 4
Background This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that is required for cell cycle progression and survival in primary astrocytes and may be involved in the regulation of mitogenic signalling in vascular smooth muscles cells. Alternative splicing results in multiple transcripts encoding different isoforms.
Synonyms NDRG4; NDRG family member 4; protein NDRG4; KIAA1180; SMAP 8; smooth muscle-associated protein 8; brain development-related molecule 1; vascular smooth muscle cell-associated protein 8; BDM1; SMAP8; SMAP-8; FLJ30586; FLJ42011; MGC19632; DKFZp686I1615
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human NDRG4-3928HCL Recombinant Human NDRG4 293 Cell Lysate HEK293 N/A
    Human NDRG4-520H Recombinant Human NDRG4 Protein, His-tagged E.coli His
    Mouse NDRG4-10506M Recombinant Mouse NDRG4 Protein Mammalian Cell His
    Zebrafish NDRG4-4201Z Recombinant Zebrafish NDRG4 Mammalian Cell His

    ndrg4 involved in several pathways and played different roles in them. We selected most pathways ndrg4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ndrg4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    ndrg4 has several biochemical functions, for example, molecular_function, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ndrg4 itself. We selected most functions ndrg4 had, and list some proteins which have the same functions with ndrg4. You can find most of the proteins on our site.

    Function Related Protein
    molecular_function BRI3BP; TC2N; SPECC1LA; PORCNL; ILDR1A; RPRMB; RTN1A; PTGES3L; LINS; SSUH2.3
    protein binding SOX30; CIB3; COG2; SMIM3; DCPS; PDLIM5; PIK3CA; RNF2; SENP1; LOXL2

    ndrg4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ndrg4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ndrg4.


    Liu, XP; Hu, XL; et al. Preparation and Application of Monoclonal Antibody Against hNDRG2. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY 152:306-315(2009).
    Okuda, T; Kokame, K; et al. Differential expression patterns of NDRG family proteins in the central nervous system. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 56:175-182(2008).
    Nakada, N; Hongo, S; et al. Molecular characterization of NDRG4/Bdm1 protein isoforms that are differentially regulated during rat brain development. DEVELOPMENTAL BRAIN RESEARCH 135:45-53(2002).

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