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NEUROG3

  • Official Full Name

    neurogenin 3

  • Overview

    The protein encoded by this gene is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of congenital malabsorptive diarrhea 4 (DIAR4).
  • Synonyms

    NEUROG3; neurogenin 3; neurogenin-3; Atoh5; bHLHa7; Math4B; ngn3; ATH4B; Class A basic helix-loop-helix protein 7; NGN-3; NGN3_HUMAN; OTTHUMP00000019730; Protein atonal homolog 5;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • His
  • Fc
  • Avi
  • Myc
  • DDK
  • N
  • C
  • Non
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NEUROG3-1269H Recombinant Human NEUROG3, GST-tagged E.coli GST 1-213aa
Human NEUROG3-725H Recombinant Human NEUROG3 Mammalian Cell His
Human NEUROG3-5002H Recombinant Human NEUROG3, His-tagged E.coli His
Human NEUROG3-401H Recombinant Human neurogenin 3, His-tagged E.coli His 1-214
Human NEUROG3-3863HCL Recombinant Human NEUROG3 293 Cell Lysate HEK293 Non
Human NEUROG3-787H Recombinant Human NEUROG3 Protein, His-tagged E.coli His Arg93~Leu214
Human NEUROG3-3616H-B Recombinant Human NEUROG3 Protein Pre-coupled Magnetic Beads HEK293
Human NEUROG3-3616H Recombinant Human NEUROG3 Protein, His (Fc)-Avi-tagged HEK293 His&Fc&Avi
Human NEUROG3-794H Recombinant Human NEUROG3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc&DDK
Human NEUROG3-1439H Recombinant Human NEUROG3 protein(1-214aa), His&Myc-tagged E.coli N-His&C-Myc 1-214aa
Mouse NEUROG3-10604M Recombinant Mouse NEUROG3 Protein Mammalian Cell His
Mouse Neurog3-662M Recombinant Mouse Neurog3 Protein, MYC/DDK-tagged HEK293T Myc&DDK
Mouse NEUROG3-6027M Recombinant Mouse NEUROG3 Protein, His (Fc)-Avi-tagged HEK293 His&Fc&Avi
Mouse NEUROG3-6027M-B Recombinant Mouse NEUROG3 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish NEUROG3-9326Z Recombinant Zebrafish NEUROG3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

NEUROG3 involved in several pathways and played different roles in them. We selected most pathways NEUROG3 participated on our site, such as Maturity onset diabetes of the young, which may be useful for your reference. Also, other proteins which involved in the same pathway with NEUROG3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Maturity onset diabetes of the youngBHLHA15;INS2;NR5A2;MNX1;NEUROD1;NKX6;INS1;ONECUT1;INS

NEUROG3 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, chromatin DNA binding, core promoter binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NEUROG3 itself. We selected most functions NEUROG3 had, and list some proteins which have the same functions with NEUROG3. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II core promoter proximal region sequence-specific DNA bindingBATF;KDM6A;CARF;FOXD1;EGR2;ARNT2;GLI2;DLX4;POU2F2
chromatin DNA bindingNOTCH1;HIST1H1D;THRB;PPARGC1A;H2AFY2;NKAP;RARA;H1F0;VAX2
core promoter bindingPSPC1;HDAC5;REST;SAFB;XBP1;SFPQ;E2F7;PYDC3;CLOCK
protein bindingTYROBP;MTERF;NOSTRIN;CCDC28B;TRAM2;FYTTD1;JAG2;TRIM37;HHEX
protein dimerization activityAHRRA;MXD1;BHLHE41;DBI;MESPAA;MEF2CB;POLR2J2;HER15.1;TWIST1B
transcription coactivator activityE4F1;PIAS1;MNT;NCOA1;NFATC4;CREBBP;SAP130;DYRK1B;ATXN7L3
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingPHOX2B;ARID3B;SOX12;NUCKS1;SFPI1;CDX4;SOX2;NR4A2;MZF1
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific bindingNKX6-2;SKIL;NFIL3-4;TFAP2C;EN1;IFI203;REST;NKX3-2;HINFP

NEUROG3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NEUROG3 here. Most of them are supplied by our site. Hope this information will be useful for your research of NEUROG3.

REL; TCF12

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