NFIC

  • Official Full Name

    nuclear factor I/C (CCAAT-binding transcription factor)

  • Overview

    The protein encoded by this gene belongs to the CTF/NF-I family. These are dimeric DNA-binding proteins, and function as cellular transcription factors and as replication factors for adenovirus DNA replication. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

  • Synonyms

    NFIC;nuclear factor I/C (CCAAT-binding transcription factor);NFI;nuclear factor 1 C-type;CTF;CTF5;NF I;NF1-C;NF-I/C;TGGCA-binding protein;CCAAT-box-binding transcription factor;NF-I;MGC20153

Recombinant Proteins

  • Human
  • Mouse
  • Chicken
  • E.coli
  • Mammalian Cells
  • HEK293
  • HEK293T
  • GST
  • His
  • Non
  • Flag
  • DDK
  • Myc
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
NFIC-1279H Recombinant Human NFIC, GST-tagged E.coli Human GST 1-351
NFIC-325H Active Recombinant Human NFIC, GST-tagged E.coli Human GST 399-499 a.a.
NFIC-10619M Recombinant Mouse NFIC Protein Mammalian Cells Mouse His
NFIC-30377TH Recombinant Human NFIC E.coli Human Non
NFIC-30378TH Recombinant Human NFIC, His-tagged Human His Full L. 1-499 a.a.
NFIC-6823C Recombinant Chicken NFIC Mammalian Cells Chicken His
NFIC-3851HCL Recombinant Human NFIC 293 Cell Lysate HEK293 Human Non
NFIC-33HFL Active Recombinant Full Length Human NFIC Protein, Flag tagged HEK293T Human Flag Full L.
Nfic-4395M Recombinant Mouse Nfic Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
NFIC-514H Recombinant Human NFIC Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
NFIC-6036M Recombinant Mouse NFIC Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
NFIC-6036M-B Recombinant Mouse NFIC Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    NFIC involved in several pathways and played different roles in them. We selected most pathways NFIC participated on our site, such as FOXA1 transcription factor network,Gene Expression,RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription, which may be useful for your reference. Also, other proteins which involved in the same pathway with NFIC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    RNA Polymerase III Transcription Termination NFIX,NFIA,NFIB
    FOXA1 transcription factor network DSCAM,CEBPB,AP1B1,NR2F2,FOXA1,POU2F1,NFIA,NRIP1,TFF1,CYP2C18
    RNA Polymerase III Abortive And Retractive Initiation SNAPC5,ZNF143,BRF1,GTF3C2,NFIB,GTF3C4,GTF3C3,SNAPC2,SNAPC3,POU2F1
    RNA Polymerase III Transcription GTF3A,SNAPC1,GTF3C5,ZNF143B,NFIA,POLR3GLA,BRF1,ZNF143A,GTF3AA,GTF3AB
    RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription TFB2M,MTA3,POLR3GLA,MTA1,BRF1,POU2F1B,PTRF,GTF3AA,MBD3,MBD3B
    Gene Expression ZNF643,ZNF621,NR2F1B,USP9X,SAP30BP,SF3A1,WARS2,SURF1,A1CF,ZNF688

    Protein Function

    NFIC has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,transcription factor activity, sequence-specific DNA binding,transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NFIC itself. We selected most functions NFIC had, and list some proteins which have the same functions with NFIC. You can find most of the proteins on our site.

    Function Related Protein
    RNA polymerase II core promoter proximal region sequence-specific DNA binding ETV4,OVOL1,RBPJ,MZF1,RFX1,ATF7,RBPJB,SRF,SMAD2,CEBPA
    transcription factor activity, sequence-specific DNA binding FOXG1D,ZNF83,OTX1B,ZNF182,SCML1,HIVEP2,Aff1,SIM1A,NR1H4,ETV5B
    transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GLIS2,ZFAT,HOXA10,TCF21,ELK3,TTC6,CDX4,BCL11B,NFIB,FOSB

    Interacting Protein

    NFIC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NFIC here. Most of them are supplied by our site. Hope this information will be useful for your research of NFIC.

    saicar;PKM;HSP90AB1;PARP1;q96hz8_human;TPD52L3;LLPH;TKTL2;ZKSCAN7;mdm2_human_probe;SNW1

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