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NFIC

Official Full Name

nuclear factor I/C (CCAAT-binding transcription factor)
Overview

The protein encoded by this gene belongs to the CTF/NF-I family. These are dimeric DNA-binding proteins, and function as cellular transcription factors and as replication factors for adenovirus DNA replication. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Synonyms

NFIC; nuclear factor I/C (CCAAT-binding transcription factor); NFI; nuclear factor 1 C-type; CTF; CTF5; NF I; NF1-C; NF-I/C; TGGCA-binding protein; CCAAT-box-binding transcription factor; NF-I; MGC20153;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	NFIC-325H	Active Recombinant Human NFIC, GST-tagged	E.coli	GST		Inquiry
Human	NFIC-1279H	Recombinant Human NFIC, GST-tagged	E.coli	GST	1-351	$319 / 25ug
Human	NFIC-30378TH	Recombinant Human NFIC, His-tagged		His		Inquiry
Human	NFIC-30377TH	Recombinant Human NFIC	E.coli	N/A		Inquiry
Human	NFIC-3851HCL	Recombinant Human NFIC 293 Cell Lysate	HEK293	N/A		Inquiry
Human	NFIC-514H	Recombinant Human NFIC Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Mouse	NFIC-10619M	Recombinant Mouse NFIC Protein	Mammalian Cell	His		Inquiry
Mouse	NFIC-6036M-B	Recombinant Mouse NFIC Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	Nfic-4395M	Recombinant Mouse Nfic Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Mouse	NFIC-6036M	Recombinant Mouse NFIC Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Chicken	NFIC-6823C	Recombinant Chicken NFIC	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

NFIC involved in several pathways and played different roles in them. We selected most pathways NFIC participated on our site, such as FOXA1 transcription factor network, Gene Expression, RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription, which may be useful for your reference. Also, other proteins which involved in the same pathway with NFIC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
FOXA1 transcription factor network	NFIC;DSCAM;NR2F2;CYP2C18;NRIP1;NFIB;CEBPB;NFIA;CC10
Gene Expression	ZNF26;ZNF19;ZNF468;EIF4B;NR2F6A;ZNF559;ZNF41;GTF3C3;HNRNPR
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription	SNAPC1B;ZNF143B;MTA1;GATAD2AB;GTF3A;BRF1;GTF3C2;GTF3C5;TFB2M
RNA Polymerase III Abortive And Retractive Initiation	GTF3C2;NFIX;GTF3C5;SNAPC1;CRCP;SNAPC4;SNAPC2;BRF1;BRF2
RNA Polymerase III Transcription	GTF3C3;ZNF143;SNAPC2;SNAPC1;POLR3GLA;NFIA;NFIB;SNAPC5;NFIC
RNA Polymerase III Transcription Termination	NFIC;NFIB;NFIA;NFIX

NFIC has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, transcription factor activity, sequence-specific DNA binding, transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NFIC itself. We selected most functions NFIC had, and list some proteins which have the same functions with NFIC. You can find most of the proteins on our site.

Function	Related Protein
RNA polymerase II core promoter proximal region sequence-specific DNA binding	ISL1;RAX;FOXD1;SP1;ZIC3;NKX3-2;SIX4;ATF3;TCF3A
transcription factor activity, sequence-specific DNA binding	ZC3H8;ZNF621;GRHL2B;DEAF1;ZFP516;ZNF643;PURBA;ZNF500;NOTCH1
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	ISL1;MIXL1;RELA;CEBPZ;NR4A2;MITF;SIX1;DLX5;EGR1

NFIC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NFIC here. Most of them are supplied by our site. Hope this information will be useful for your research of NFIC.

saicar; PKM; HSP90AB1; PARP1; q96hz8_human; TPD52L3; LLPH; TKTL2; ZKSCAN7; mdm2_human_probe; SNW1