NGFR

  • Official Full Name

    nerve growth factor receptor

  • Overview

    receptor that can bind NGF, BDNF, NT-3, and NT-4 [RGD, Feb 2006]
  • Synonyms

    NGFR; nerve growth factor receptor; p75; LNGFR; p75NTR; RNNGFRR; Tnfrsf16; tumor necrosis factor receptor superfamily member 16; p75 ICD; gp80-LNGFR; NGF receptor; nerve growth factor receptor, fast; low affinity nerve growth factor receptor; low affinity neurotrophin receptor p75NTR; low-affinity nerve growth factor receptor; nerve growth factor receptor (TNFR superfamily, member 16);

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chromatography Reagents
  • Chicken
  • Gallus gallus (Chicken)
  • Human
  • Mouse
  • Rabbit
  • Rattus norvegicus (Rat)
  • Rhesus monkey
  • CHO
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human Cell
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • C
  • Fc
  • hFc
  • His
  • Flag
  • hIgG1
  • hIgG4
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NGFR-653H Active Recombinant Human NGFR, Fc-tagged, Biotinylated Human Cell Fc
Human NGFR-1575H Recombinant Human Nerve Growth Factor Receptor (TNFR Superfamily, Member 16) CHO N/A
Human NGFR-292H Recombinant Human NGFR Mammalian Cell His
Human NGFR-452H Recombinant Human NGFR, 209aa, Fc Chimera HEK293 Fc
Human NGFR-453H Recombinant Human NGFR, 222aa, Fc Chimera HEK293 Fc
Human NGFR-6992H Recombinant Human NGFR protein(Met1-Asn250), hFc-tagged HEK293 C-hFc Met1-Asn250
Human NGFR-30619TH Recombinant Human NGFR, Fc-tagged Fc
Human NGFR-6993H Recombinant Human NGFR protein(Met1-Asn250), His-tagged HEK293 C-His Met1-Asn250
Human NGFR-80H Recombinant Human NGFR protein, His-tagged Insect Cell His
Human NGFR-1670HCL Recombinant Human NGFR cell lysate Human Cell N/A
Human NGFR-1509H-B Recombinant Human NGFR Protein Pre-coupled Magnetic Beads HEK293
Human NGFR-1509H Recombinant Human NGFR Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human NGFR-106H Recombinant Human NGFR Protein, His-tagged E.coli His
Human NGFR-4307H Recombinant Human NGFR Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human NGFR-0892H Recombinant Human NGFR Full Length Transmembrane protein, His-Avi-tagged, Biotinylated HEK293 His-Avi 29-427aa
Human NGFR-1254H Recombinant Human NGFR Protein (Lys29-Asn250), N-His tagged E.coli N-His Lys29-Asn250
Human NGFR-169N Active Recombinant Human NGFR Protein HEK293
Human NGFR-1099HFL Recombinant Full Length Human NGFR Protein, C-Flag-tagged Mammalian cells Flag
Human NGFR-604M NGFR protein-coupled magnetic MicroBeads
Human NGFR-4704H Recombinant Human NGFR Protein (Met1-Asn250), C-His tagged Mammalian cells C-His Met1-Asn250
Mouse NGFR-940M Active Recombinant Mouse NGFR protein, hFc-tagged HEK293 hFc Met1-Asn253
Mouse Ngfr-1769M Recombinant Mouse Nerve Growth Factor Receptor, Fc-tagged Mammalian cells Fc
Mouse Ngfr-6994M Recombinant Mouse Ngfr protein(Met1-Asn243), His-tagged HEK293 C-His Met1-Asn243
Mouse NGFR-1679MCL Recombinant Mouse NGFR cell lysate Human Cell N/A
Mouse Ngfr-93M Recombinant Mouse Ngfr Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Ngfr-5719M Recombinant Mouse Ngfr Protein (Gly20-Asn243), C-Fc tagged Mammalian cells C-Fc Gly20-Asn243
Mouse Ngfr-93M-B Recombinant Mouse Ngfr Protein Pre-coupled Magnetic Beads HEK293
Mouse Ngfr-4408M Recombinant Mouse Ngfr Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus monkey NGFR-1656R Recombinant Rhesus Monkey NGFR Protein, hIgG1-tagged HEK293 hIgG1
Rhesus monkey NGFR-1655R Recombinant Rhesus Monkey NGFR Protein HEK293 N/A
Rhesus monkey NGFR-1657R Recombinant Rhesus Monkey NGFR Protein, hIgG4-tagged HEK293 hIgG4
Rabbit NGFR-502R Recombinant Rabbit NGFR Protein, His-tagged HEK293 His Met1-Asp242
Rabbit NGFR-503R Recombinant Rabbit NGFR protein(Met1-Asp242), hFc-tagged HEK293 C-hFc Met1-Asp242
Gallus gallus (Chicken) RFL259GF Recombinant Full Length Chicken Tumor Necrosis Factor Receptor Superfamily Member 16(Ngfr) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (20-416)
Rattus norvegicus (Rat) RFL16609RF Recombinant Full Length Rat Tumor Necrosis Factor Receptor Superfamily Member 16(Ngfr) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (30-425)
Chicken NGFR-3928C Recombinant Chicken NGFR Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource
  • NGFR Related Signal Pathway

NGFR involved in several pathways and played different roles in them. We selected most pathways NGFR participated on our site, such as Ras signaling pathway, Rap signaling pathway, Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with NGFR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ras signaling pathwayRAP1B;PRKACG;FGFR1;MRAS;ETS2;FGF4;RALGDS;GRIN2B;INS1
Rap signaling pathwayPIK3R2;FGF1;MAPK3;MAP2K1;ANGPT1;INSR;AKT2;FGF20;FGFR3
Cytokine-cytokine receptor interactionCXCL5;NGFR;GM13305;TNFRSF11A;CNTF;CCR8L;CXCL1;Kitl;CXCR4
PIK-Akt signaling pathwayPPP2R5B;PIK3CB;PPP2R5C;IL4;ANGPT4;COL6A4;F2R;PDPK1;Il4ra
Neurotrophin signaling pathwayCALM4;IRS1;SOS1;RAP1B;CALM3;RPS6KA3;AKT1;NTF3;MAPK1
Transcriptional misregulation in cancerREL;TLX3;FOXO1;HDAC2;PAX3;HIST1H3E;TFE3;CCNA1;Itgam&Itgb2

NGFR has several biochemical functions, for example, Rab GTPase binding, beta-amyloid binding, death receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NGFR itself. We selected most functions NGFR had, and list some proteins which have the same functions with NGFR. You can find most of the proteins on our site.

Function Related Protein
Rab GTPase bindingEVI5;RAB11FIP4B;NDRG1;RAB11FIP2;MLPH;UNC13D;MYRIP;RPH3A;NSF
beta-amyloid bindingBACE2;CHRNA7;BCHE;CLSTN1;BACE1;ACHE;SORL1;APBB1;APOE
death receptor activityTNFRSF10A;NGFR
nerve growth factor bindingPCSK6;FURIN;NGFR;NGFRB;SORT1;NTRK1
neurotrophin TRKA receptor bindingPLCG1;SHC1;FRS2;NGFR;PIK3R1;GRB2;EFNA5
neurotrophin bindingNTRK2;NTRK3;NGFR;NTRK1
preprotein binding
protein bindingPTPN7;ZNF843;KRTAP8-1;PFKL;TRIM50;GSG1L;C11orf68;PTRH2;ACE
tumor necrosis factor-activated receptor activityEDA2R;CD40;TNFRSF25;TNFRSF19;TNFRSF10A;TNFRSF11A;NGFRB;TNFRSF4;TNFRSF6B
ubiquitin protein ligase bindingMAP1LC3C;TANK;LRPPRC;EGR2;GPI;TRAF1;CASC3;TRAF3;UBE2KB

NGFR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NGFR here. Most of them are supplied by our site. Hope this information will be useful for your research of NGFR.

Gene Family

TNF

Research Area

Related articles

Suzuki, N; Takata, M; et al. Assessment of Melanoma-Initiating Cell Markers and Conventional Parameters in Sentinel Lymph Nodes of Malignant Melanoma. ACTA MEDICA OKAYAMA 69:17-27(2015).
Murillo-Sauca, O; Chung, MK; et al. CD271 is a functional and targetable marker of tumor-initiating cells in head and neck squamous cell carcinoma. ONCOTARGET 5:6854-6866(2014).
  • Reviews
  • Q&As

Customer Reviews (3)

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Reviews
06/22/2022

    Its usage in ELISA and protein electron microscopy structure analysis has been reported to yield highly reproducible and interpretable results, providing valuable insights into the molecular mechanisms and biological processes under investigation.

    09/02/2020

      Its excellent performance in ELISA assays makes it a valuable tool in quantifying analytes in biological samples.

      11/29/2018

        Its reliability, specificity, and versatility make it an invaluable asset in studying and understanding complex biological systems.

        Q&As (5)

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        How is NGFR protein involved in neurodegenerative diseases? 12/21/2022

        NGFR protein is involved in the survival and maintenance of nerve cells, and its dysregulation has been associated with neurodegenerative diseases such as Alzheimer's and Parkinson's disease.

        Can NGFR protein be targeted for the treatment of neuropathic pain? 07/01/2022

        Research into NGFR protein as a potential target for the development of novel pain therapies is ongoing, with the aim of modulating pain signaling pathways.

        Are there any therapeutic applications of NGFR protein in neurodegenerative diseases? 05/20/2018

        Some studies have explored the potential of NGFR protein as a therapeutic target for neurodegenerative diseases, with the aim of promoting nerve cell survival and function.

        Can NGFR protein be used as a biomarker for neurodegenerative diseases? 06/27/2017

        Research suggests that alterations in NGFR protein levels may serve as a potential biomarker for neurodegenerative diseases, aiding in early diagnosis and monitoring disease progression.

        How is NGFR protein being studied in the context of nerve regeneration? 12/03/2016

        NGFR protein is being investigated for its potential role in promoting nerve regeneration after injury, with the aim of developing new treatments for nerve damage and paralysis.

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