Recombinant Human NGFR protein, His-tagged
Cat.No. : | NGFR-80H |
Product Overview : | Recombinant human NGFR, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | NGFR, also known as tumor necrosis factor receptor superfamily member 16, is a member of the tumor necrosis factor receptor superfamily with a widespread pattern of expression in tissues such as the brain, liver, lung, and muscle. It plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake. They are low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. It can mediate cell survival as well as cell death of neural cells. |
Source : | Insect cell |
Species : | Human |
Tag : | His |
Form : | Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
Molecular Mass : | 24.6kDa (230aa)40-57kDa (SDS-PAGE under reducing conditions) |
AA Sequence : | KEACPTGLYT HSGECCKACN LGEGVAQPCG ANQTVCEPCL DSVTFSDVVS ATEPCKPCTE CVGLQSMSAP CVEADDAVCR CAYGYYQDETTGRCEACRVC EAGSGLVFSC QDKQNTVCEE CPDGTYSDEA NHVDPCLPCT VCEDTERQLR ECTRWADAEC EEIPGRWITR STPPEGSDSTAPSTQEPEAP PEQDLIASTV AGVVTTVMGS SQPVVTRGTT DNLEHHHHHH |
Endotoxin : | < 1.0 EU per 1 microgram of protein (determined by LAL method) |
Purity : | >95% by SDS – PAGE |
Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 1mg/ml (determined by Absorbance at 280nm) |
Gene Name : | NGFR nerve growth factor receptor [ Homo sapiens ] |
Official Symbol : | NGFR |
Synonyms : | NGFR; nerve growth factor receptor; nerve growth factor receptor (TNFR superfamily, member 16); tumor necrosis factor receptor superfamily member 16; CD271; low affinity nerve growth factor receptor; p75NTR; TNFR superfamily; member 16; TNFRSF16; p75 ICD; NGF receptor; TNFR superfamily, member 16; low affinity neurotrophin receptor p75NTR; low-affinity nerve growth factor receptor; p75(NTR); Gp80-LNGFR; |
Gene ID : | 4804 |
mRNA Refseq : | NM_002507 |
Protein Refseq : | NP_002498 |
MIM : | 162010 |
UniProt ID : | P08138 |
Chromosome Location : | 17q21-q22 |
Pathway : | Axonal growth inhibition (RHOA activation), organism-specific biosystem; Axonal growth stimulation, organism-specific biosystem; Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; Ceramide signalling, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; NADE modulates death signalling, organism-specific biosystem; |
Function : | death receptor activity; nerve growth factor binding; protein binding; receptor activity; signal transducer activity; transmembrane signaling receptor activity; |
Products Types
◆ Recombinant Protein | ||
Ngfr-4408M | Recombinant Mouse Ngfr Protein, Myc/DDK-tagged | +Inquiry |
NGFR-503R | Recombinant Rabbit NGFR Protein, Fc-tagged | +Inquiry |
Ngfr-6994M | Recombinant Mouse Ngfr protein(Met1-Asn243), His-tagged | +Inquiry |
NGFR-1509H | Recombinant Human NGFR Protein, His (Fc)-Avi-tagged | +Inquiry |
NGFR-6992H | Recombinant Human NGFR protein(Met1-Asn250), hFc-tagged | +Inquiry |
◆ Lysates | ||
NGFR-1670HCL | Recombinant Human NGFR cell lysate | +Inquiry |
NGFR-1679MCL | Recombinant Mouse NGFR cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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