NOTUM
-
Official Full Name
notum pectinacetylesterase homolog
-
Synonyms
NOTUM; notum pectinacetylesterase homolog (Drosophila); protein notum homolog;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- Mamanlian cells
- Mammalian Cell
- Mammalian cells
- Flag
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | NOTUM-1335H | Recombinant Human NOTUM protein, MYC/DDK-tagged | HEK293 | Myc/DDK |
|
|
| Human | NOTUM-1334H | Recombinant Human NOTUM, His-tagged | E.coli | His | 76-430aa | |
| Human | NOTUM-3754HCL | Recombinant Human NOTUM 293 Cell Lysate | HEK293 | N/A |
|
|
| Human | NOTUM-1624H | Recombinant Human NOTUM Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK |
|
|
| Human | NOTUM-1098HFL | Recombinant Full Length Human NOTUM protein, Flag-tagged | Mamanlian cells | Flag |
|
|
| Mouse | NOTUM-25M | Active Recombinant Mouse Notum Protein, His-tagged | Mammalian cells | His |
|
|
| Mouse | NOTUM-10794M | Recombinant Mouse NOTUM Protein | Mammalian Cell | His |
|
|
| Mouse | Notum-1434M | Recombinant Mouse Notum Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
|
|
| Mouse | NOTUM-6142M | Recombinant Mouse NOTUM Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
|
|
| Mouse | NOTUM-6142M-B | Recombinant Mouse NOTUM Protein Pre-coupled Magnetic Beads | HEK293 |
|
- Involved Pathway
- Protein Function
- Interacting Protein
- NOTUM Related Articles
NOTUM involved in several pathways and played different roles in them. We selected most pathways NOTUM participated on our site, such as Hedgehog ligand biogenesis, Release of Hh-Np from the secreting cell, Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with NOTUM were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Hedgehog ligand biogenesis | NOTUM;NOTUM1A;DISP2;GPC5A;HHAT;OS9;DERL2;SCUBE2 |
| Release of Hh-Np from the secreting cell | DISP2;SCUBE2;NOTUM;NOTUM1A |
| Signal Transduction | GNA13B;PYYA;OMG;IFT122;KIDINS220B;PCSK6;GHRB;IFT88;ARAP1 |
| Signaling by Hedgehog | CDC73;KIF7;SCUBE2;EVC2;IQCE;BBS13;IFT52;IFT88;EVC |
NOTUM has several biochemical functions, for example, palmitoleyl hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NOTUM itself. We selected most functions NOTUM had, and list some proteins which have the same functions with NOTUM. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| palmitoleyl hydrolase activity | NOTUM;NOTUM1A;NOTUM1B |
NOTUM has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NOTUM here. Most of them are supplied by our site. Hope this information will be useful for your research of NOTUM.
- Q&As
- Reviews
Q&As (5)
Ask a questionNOTUM's role in Wnt signaling modulation has implications for neurodegenerative disorders, and targeting NOTUM may offer therapeutic avenues for conditions such as Alzheimer's disease.
NOTUM is involved in the regulation of stem cell behavior through its influence on Wnt signaling, making it a target for manipulating stem cell activities.
Several clinical trials are underway to investigate the safety and efficacy of NOTUM inhibitors in cancer patients, providing valuable insights into their clinical potential.
NOTUM's role in regulating Wnt signaling contributes to tissue homeostasis, and understanding this mechanism can provide insights into maintaining tissue health.
Understanding individual variations in NOTUM expression and activity may allow for personalized treatment strategies, tailoring interventions based on a patient's molecular profile.
Customer Reviews (3)
Write a reviewIts excellent performance in ELISA assays makes it a valuable tool in quantifying analytes in biological samples.
Its reliability, specificity, and versatility make it an invaluable asset in studying and understanding complex biological systems.
Its usage in ELISA and protein electron microscopy structure analysis has been reported to yield highly reproducible and interpretable results, providing valuable insights into the molecular mechanisms and biological processes under investigation.
Ask a Question for All NOTUM Products
Required fields are marked with *
My Review for All NOTUM Products
Required fields are marked with *
