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NR2E1

  • Official Full Name

    NR2E1 nuclear receptor subfamily 2, group E, member 1

  • Synonyms

    NR2E1; nuclear receptor subfamily 2, group E, member 1; TLX; nuclear receptor subfamily 2 group E member 1; TLL; XTLL; hTll; tailless homolog; nuclear receptor TLX; tailes-related receptor; protein tailless homolog;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
  • T7|His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NR2E1-130H Recombinant Human NR2E1 protein, T7/His-tagged E.coli T7/His
Human NR2E1-1216HCL Recombinant Human NR2E1 cell lysate N/A
Human NR2E1-6081H Recombinant Human NR2E1 Protein, GST-tagged Wheat Germ GST
Human NR2E1-6738HF Recombinant Full Length Human NR2E1 Protein, GST-tagged In Vitro Cell Free System GST 385 amino acids
Mouse NR2E1-10864M Recombinant Mouse NR2E1 Protein Mammalian Cell His
Mouse NR2E1-6186M Recombinant Mouse NR2E1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse NR2E1-6186M-B Recombinant Mouse NR2E1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque NR2E1-3095R Recombinant Rhesus monkey NR2E1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque NR2E1-2914R Recombinant Rhesus Macaque NR2E1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque NR2E1-2914R-B Recombinant Rhesus Macaque NR2E1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish NR2E1-1034Z Recombinant Zebrafish NR2E1 Mammalian Cell His
Chicken NR2E1-6725C Recombinant Chicken NR2E1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • NR2E1 Related Articles

NR2E1 involved in several pathways and played different roles in them. We selected most pathways NR2E1 participated on our site, such as Gene Expression, Generic Transcription Pathway, Nuclear Receptor transcription pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NR2E1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Gene ExpressionMED13A;TNPO1;SAP18;NRBF2B;EEF1E1;ZNF740;PHF19;NR4A2A;ESR2A
Generic Transcription PathwayZNF620;ZNF606;ZNF287;ZNF71;ZNF461;KRBA1;MED25;TACO1;ZNF433
Nuclear Receptor transcription pathwayRARGA;NR0B2A;NRBP1;NR0B1;NR1D2A;NR2F6;ESRRGA;NR2E1;NR6A1
Nuclear ReceptorsRARGA;NR5A1;NR2E1;VDRB;RORAA;RARG;NR1I2;NR1D2B;NR1I3

NR2E1 has several biochemical functions, for example, histone deacetylase binding, sequence-specific DNA binding, steroid hormone receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NR2E1 itself. We selected most functions NR2E1 had, and list some proteins which have the same functions with NR2E1. You can find most of the proteins on our site.

Function Related Protein
histone deacetylase bindingD7ERTD443E;YWHAE;CEBPA;ANKRA2;RUNX2;ANKRD1;NRIP1;PKN2;PHB
sequence-specific DNA bindingLHX2;RORAA;DMRT3A;IRF4;ZNF215;CUX1;POU2F1;DLX3;OSR2
steroid hormone receptor activityESR1;ESR2A;VDRA;GPR30;NR1D2;RARG;RORCB;PGR;THRAA
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingSOX9;TRP63;NOBOX;PAX5;MAFB;SOX12;NFIB;SIX2;FOXC2
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific bindingTFAP2A;NFATC4;KLF16;REST;FOXO1;ZBTB20;IFI203;MLXIPL;YY1
zinc ion bindingRNF214;ZCCHC2;SEC24D;GALT;FTR67;TAF15;PRICKLE1B;ZRANB1;PAPPA

NR2E1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NR2E1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NR2E1.

Olausson, KH; Maire, CL; et al. Prominin-1 (CD133) Defines Both Stem and Non-Stem Cell Populations in CNS Development and Gliomas. PLOS ONE 9:-(2014).
Gopisetty, G; Xu, J; et al. Epigenetic regulation of CD133/PROM1 expression in glioma stem cells by Sp1/myc and promoter methylation. ONCOGENE 32:3119-3129(2013).
  • Q&As
  • Reviews

Q&As (5)

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Can NR2E1 be a target for cancer therapy? 05/13/2022

Some studies suggest that NR2E1 may have implications in cancer therapy, particularly in the context of glioblastoma and other brain tumors.

Write 15 questions and answers about the clinical application of GATA1 protein in English 02/27/2022

NR2E1 is being investigated for its potential therapeutic applications in neurological disorders, including neurodegenerative diseases and brain injuries.

Can NR2E1 be a potential target for regenerative medicine? 05/29/2020

The regulatory role of NR2E1 in neural stem cells makes it a potential target for regenerative medicine strategies aimed at repairing and replacing damaged neural tissue.

How is NR2E1 linked to retinoid signaling pathways? 02/21/2020

NR2E1 is known to interact with retinoid signaling pathways, and its activity is influenced by retinoic acid, suggesting a connection to cellular differentiation processes.

How does NR2E1 influence the development of the central nervous system? 12/31/2019

NR2E1 regulates the development of the central nervous system by modulating the fate of neural progenitor cells and influencing the formation of various brain structures.

Customer Reviews (3)

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Reviews
10/11/2022

    Its unique properties make NR2E1 an invaluable tool for investigating cellular signaling pathways, protein-protein interactions, and membrane dynamics.

    06/23/2018

      With the NR2E1 protein and its accompanying technical assistance, I am confident that I can achieve successful outcomes for my research endeavors.

      10/28/2017

        The NR2E1 protein offers numerous advantages in trials and research studies, making it an excellent choice for scientists in need of reliable and high-quality experimental materials.

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