NR2F2
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Official Full Name
NR2F2 nuclear receptor subfamily 2, group F, member 2
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Overview
This gene encodes a member of the steroid thyroid hormone superfamily of nuclear receptors. The encoded protein is a;ligand inducible transcription factor that is involved in the regulation of many different genes. Alternate splicing;results in multiple transcript variants. -
Synonyms
NR2F2; nuclear receptor subfamily 2, group F, member 2; ARP1, TFCOUP2; COUP transcription factor 2; COUP TFII; COUPTFB; NF E3; SVP40; COUP transcription factor II; apolipoprotein AI regulatory protein 1; apolipoprotein A-I regulatory protein 1; ADP-ribosylation factor related protein 1; chicken ovalbumin upstream promoter transcription factor 2; chicken ovalbumin upstream promoter-transcription factor I; chicken ovalbumin upstream promoter-transcription factor II variant 1; chicken ovalbumin upstream promoter-transcription factor II variant 2; chicken ovalbumin upstream promoter-transcription factor II variant 3; ARP1; NF-E3; NR2F1; TFCOUP2; COUPTFII; MGC117452;
- Cell & Tissue Lysates
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Zebrafish
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- Fc
- Avi
- Non
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | NR2F2-1217HCL | Recombinant Human NR2F2 cell lysate | Non |
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| Human | NR2F2-3323HF | Recombinant Full Length Human NR2F2 Protein, GST-tagged | In Vitro Cell Free System | GST | 414 amino acids |
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| Human | NR2F2-25H | Recombinant Human NR2F2 Protein, GST-tagged | Wheat Germ | GST |
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| Mouse | NR2F2-10867M | Recombinant Mouse NR2F2 Protein | Mammalian Cell | His |
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| Mouse | NR2F2-6187M | Recombinant Mouse NR2F2 Protein, His (Fc)-Avi-tagged | HEK293 | His&Fc&Avi |
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| Mouse | NR2F2-6187M-B | Recombinant Mouse NR2F2 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | NR2F2-4067R | Recombinant Rat NR2F2 Protein | Mammalian Cell | His |
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| Rat | NR2F2-3726R | Recombinant Rat NR2F2 Protein, His (Fc)-Avi-tagged | HEK293 | His&Fc&Avi |
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| Rat | NR2F2-3726R-B | Recombinant Rat NR2F2 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Zebrafish | NR2F2-8789Z | Recombinant Zebrafish NR2F2 | Mammalian Cell | His |
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| Chicken | NR2F2-5991C | Recombinant Chicken NR2F2 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
NR2F2 involved in several pathways and played different roles in them. We selected most pathways NR2F2 participated on our site, such as Developmental Biology, FOXA1 transcription factor network, Nuclear Receptors, which may be useful for your reference. Also, other proteins which involved in the same pathway with NR2F2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Developmental Biology | MED16;CLTC;TDGF1;ACTR3;CACNG3;MED7;SEMA4D;PLXNC1;SREBF2 |
| FOXA1 transcription factor network | NRIP1;NR2F2;FOXA1;AP1B1;TFF1;POU2F1;NFIA;DSCAM;CC10 |
| Nuclear Receptors | VDRB;NR0B1;RORAA;RARGB;RARGA;ROR1;NR1H3;NR2F2;NR2F1A |
| Regulation of Telomerase | TNKS;NR2F2;CMTM2A;SP3;DKC1;MXD1;PINX1 |
| Transcriptional regulation of white adipocyte differentiation | EGR2;CDK19;MED21;MED18;MED22;MED9;EBF1;NR2F2;MED19 |
NR2F2 has several biochemical functions, for example, RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding, protein binding, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NR2F2 itself. We selected most functions NR2F2 had, and list some proteins which have the same functions with NR2F2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding | AHR2;NR0B1;PGR;NR2F1A;NR2F1;NR4A2;NR2F6B;NR2F6A;PPARDB |
| protein binding | MAP3K14;SLC8A1;FCRL2;FZD2;CYBRD1;MMP14;CEP164;RNF213;GOLPH3L |
| protein homodimerization activity | CHKA;ANXA9;ATPIF1;B4GALT1;CADM1B;DSCAML1;IKBKB;ENG;EEA1 |
| retinoic acid binding | NR2F2;UGT1A9;UGT1A1;CRABP2;PTGDSB;CYP26B1;CRABP2A;CYP26A1;RARA |
| sequence-specific DNA binding | FOXE1;BPTF;NR2F6A;CUX1;ZFP110;EF1;RORB;HOXD13A;NKX2.4A |
| steroid hormone receptor activity | RORCB;NR2C1;PPARAB;ESR2A;OLFR78;NR1D1;RORAA;RORAB;RXRAB |
| transcription corepressor activity | PFDN5;PBXIP1;HSF4;KCNIP3;TAF9B;NRIP1;SSX3;CCAR1;NPAT |
| transcription factor activity, sequence-specific DNA binding | ZKSCAN5;MLLT10;FOXO3B;SIX1A;FOSL2;ZBTB25;CEBPD;PURBA;MYF6 |
| zinc ion binding | ZDHHC11;LMX1BB;RNF183;ZMIZ1A;JADE1;ADH1;VPS29;CUL9;RTN4IP1 |
NR2F2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NR2F2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NR2F2.
BIK; FAM46A; pelY; ugpQ; yvcI; SETD7; HIPK3; mdm2_human_probe; AIM2; SNW1; PYHIN1
Research Area
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewThe short half-life and high clearance properties of this recombinant protein provide great advantages for its use in emergency medical Settings because of its rapid onset of action and rapid clearance from the body.
Purity and biological activity of the proteins were excellent, which provided a strong guarantee for the accuracy of the experimental results and deserved praise.
Production process of this recombinant protein is very environmentally friendly, maximizing the use of resources and minimizing the consumption of energy by optimizing the process and equipment.
Q&As (6)
Ask a questionNR2F2 protein is involved in neurodevelopment, synapse formation and neuroprotection processes in the nervous system, and has an important impact on the normal function maintenance of the nervous system.
Yes, NR2F2 protein is involved in regulating fat metabolism, glucose metabolism and cholesterol metabolism, and plays an important role in the maintenance of energy balance and metabolic homeostasis.
Yes, some disease-causing mutations associated with the NR2F2 protein have been reported that may lead to developmental defects, cardiovascular disease, and other related diseases.
NR2F2 protein regulates the development, differentiation, and function of T and B cells in the immune system. It plays an important role in the regulation of the immune response.
NR2F2 protein is regulated by various post-translational modifications such as phosphorylation, acetylation, and ubiquitination, which can affect its stability, activity, and function.
Yes, the NR2F2 protein plays an important role in heart development and cardiovascular disease. It is involved in early cardiac development, determination of the fate of heart cells, and regulation of heart function.
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