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NR2F2

  • Official Full Name

    NR2F2 nuclear receptor subfamily 2, group F, member 2

  • Overview

    This gene encodes a member of the steroid thyroid hormone superfamily of nuclear receptors. The encoded protein is a;ligand inducible transcription factor that is involved in the regulation of many different genes. Alternate splicing;results in multiple transcript variants.
  • Synonyms

    NR2F2; nuclear receptor subfamily 2, group F, member 2; ARP1, TFCOUP2; COUP transcription factor 2; COUP TFII; COUPTFB; NF E3; SVP40; COUP transcription factor II; apolipoprotein AI regulatory protein 1; apolipoprotein A-I regulatory protein 1; ADP-ribosylation factor related protein 1; chicken ovalbumin upstream promoter transcription factor 2; chicken ovalbumin upstream promoter-transcription factor I; chicken ovalbumin upstream promoter-transcription factor II variant 1; chicken ovalbumin upstream promoter-transcription factor II variant 2; chicken ovalbumin upstream promoter-transcription factor II variant 3; ARP1; NF-E3; NR2F1; TFCOUP2; COUPTFII; MGC117452;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NR2F2-1217HCL Recombinant Human NR2F2 cell lysate N/A
Human NR2F2-3323HF Recombinant Full Length Human NR2F2 Protein, GST-tagged In Vitro Cell Free System GST 414 amino acids
Human NR2F2-25H Recombinant Human NR2F2 Protein, GST-tagged Wheat Germ GST
Mouse NR2F2-10867M Recombinant Mouse NR2F2 Protein Mammalian Cell His
Mouse NR2F2-6187M Recombinant Mouse NR2F2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse NR2F2-6187M-B Recombinant Mouse NR2F2 Protein Pre-coupled Magnetic Beads HEK293
Rat NR2F2-4067R Recombinant Rat NR2F2 Protein Mammalian Cell His
Rat NR2F2-3726R Recombinant Rat NR2F2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat NR2F2-3726R-B Recombinant Rat NR2F2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish NR2F2-8789Z Recombinant Zebrafish NR2F2 Mammalian Cell His
Chicken NR2F2-5991C Recombinant Chicken NR2F2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • NR2F2 Related Research Area

NR2F2 involved in several pathways and played different roles in them. We selected most pathways NR2F2 participated on our site, such as Developmental Biology, FOXA1 transcription factor network, Nuclear Receptors, which may be useful for your reference. Also, other proteins which involved in the same pathway with NR2F2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Developmental BiologyARPC2;NTN1A;GDNF;EFNB3B;DCC;EPHB4A;HFE2;RND1L;PAQR3B
FOXA1 transcription factor networkNRIP1;CYP2C18;NR2F2;FOXA1;POU2F1;NFIA;DSCAM;NFIC;CC10
Nuclear ReceptorsNR2F6;NR1H3;NR2F2;NR1I2;NR2F1;NR1D2B;NR5A1;RORAA;RARGB
Regulation of TelomeraseCMTM2A;PINX1;NR2F2;SP3;MXD1;TNKS;DKC1
Transcriptional regulation of white adipocyte differentiationMED21;MED22;CDK19;MED29;EGR2;MED19;MED18;NR2F2;MED9

NR2F2 has several biochemical functions, for example, RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding, protein binding, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NR2F2 itself. We selected most functions NR2F2 had, and list some proteins which have the same functions with NR2F2. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA bindingNR2F5;RORCB;NR5A1A;RXRA;NR1D2;NR0B1;NR4A1;NR2F6;AHR
protein bindingFOXO4;CRTC1;FBXO44;UBE2E2;KLF6;CPNE7;PCGF5;NCOA3;RABEP1
protein homodimerization activityFGFR1OP2;QDPR;ZNF174;GPD1B;Fzd4;HOMER2;NFS1;HM13;PVRL3
retinoic acid bindingCRABP1;UGT1A1;CYP26B1;LRAT;CRABP2;UGT1A9;CRABP1A;UGT1A3;CRABP2B
sequence-specific DNA bindingMAFBA;FOXC2;PPARD;FOXG1C;USF2;ZSCAN12;GSX2;ZKSCAN3;FOXR2
steroid hormone receptor activityRORAB;NR2F1A;NR1D2A;NR1D2;NR1H5;RARB;NR2F1B;NR6A1;NR2F6
transcription corepressor activityE2F7;SETD8;HOXC6;DMAP1;CBX4;SIRT6;BASP1;MXI1;FEV
transcription factor activity, sequence-specific DNA bindingZFP260;GM239;NR6A1B;MEF2A;PBX1;BSX;ZRANB2;ZNF207;POU2F1B
zinc ion bindingEHMT1B;ZCWPW2;TET1;KDM5BB;ABLIM1A;CAR5A;RBM4.1;ABLIM3;BRD1B

NR2F2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NR2F2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NR2F2.

BIK; FAM46A; pelY; ugpQ; yvcI; SETD7; HIPK3; mdm2_human_probe; AIM2; SNW1; PYHIN1

  • Q&As
  • Reviews

Q&As (6)

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What is the function of NR2F2 protein in the nervous system? 08/19/2019

NR2F2 protein is involved in neurodevelopment, synapse formation and neuroprotection processes in the nervous system, and has an important impact on the normal function maintenance of the nervous system.

Is NR2F2 protein involved in metabolic regulation? 07/18/2019

Yes, NR2F2 protein is involved in regulating fat metabolism, glucose metabolism and cholesterol metabolism, and plays an important role in the maintenance of energy balance and metabolic homeostasis.

Are there pathogenic mutations associated with the NR2F2 protein? 06/19/2019

Yes, some disease-causing mutations associated with the NR2F2 protein have been reported that may lead to developmental defects, cardiovascular disease, and other related diseases.

What is the role of NR2F2 protein in the immune system? 05/20/2019

NR2F2 protein regulates the development, differentiation, and function of T and B cells in the immune system. It plays an important role in the regulation of the immune response.

What are the post-translational modifications of NR2F2 protein? 03/12/2019

NR2F2 protein is regulated by various post-translational modifications such as phosphorylation, acetylation, and ubiquitination, which can affect its stability, activity, and function.

Is NR2F2 protein related to heart development and function? 02/26/2019

Yes, the NR2F2 protein plays an important role in heart development and cardiovascular disease. It is involved in early cardiac development, determination of the fate of heart cells, and regulation of heart function.

Customer Reviews (3)

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Reviews
12/08/2022

    The short half-life and high clearance properties of this recombinant protein provide great advantages for its use in emergency medical Settings because of its rapid onset of action and rapid clearance from the body.

    02/10/2022

      Purity and biological activity of the proteins were excellent, which provided a strong guarantee for the accuracy of the experimental results and deserved praise.

      10/24/2020

        Production process of this recombinant protein is very environmentally friendly, maximizing the use of resources and minimizing the consumption of energy by optimizing the process and equipment.

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